The immune system: a neglected challenge for network theorists

The immune system is an N-dimensional network that has memory and learns. The system is compared with feedforward and recurrent neural networks, and it is suggested that more attention should be paid to this field by theorists. A symmetrical network model of the immune system is briefly outlined.<<ETX>>

[1]  J M Andrieu,et al.  AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications. , 1986, AIDS research.

[2]  Geoffrey W. Hoffmann,et al.  On I-J, a Network Centre Pole and AIDS , 1988 .

[3]  G W Hoffmann,et al.  On network theory and H-2 restriction. , 1980, Contemporary topics in immunobiology.

[4]  G W Hoffmann,et al.  Qualitative dynamics of a network model of regulation of the immune system: a rationale for the IgM to IgG switch. , 1982, Journal of Theoretical Biology.

[5]  N. K. Jerne,et al.  The immune system. , 1973, Scientific American.

[6]  D. Stites,et al.  Hypothesis: AIDS is an autoimmune disease directed at the immune system and triggered by a lymphotropic retrovirus. , 1986, Clinical immunology and immunopathology.

[7]  John L. Spouge,et al.  Increasing stability with complexity in a system composed of unstable subsystems , 1986 .

[8]  Luc Montagnier,et al.  Immunology: Approaches to AIDS therapy , 1986, Nature.

[9]  J J Hopfield,et al.  Neural networks and physical systems with emergent collective computational abilities. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[10]  Shearer Gm AIDS: an autoimmune pathologic model for the destruction of a subset of helper T lymphocytes. , 1986 .

[11]  A. Coutinho,et al.  IMMUNOLOGICAL CONSEQUENCES OF HIV INFECTION: ADVANTAGE OF BEING LOW RESPONDER CASTS DOUBTS ON VACCINE DEVELOPMENT , 1988, The Lancet.

[12]  P. Richter,et al.  A network theory of the immune system , 1975, European journal of immunology.