High contrast computed tomography with synchrotron radiation

This article describes a new monochromatic x‐ray CT system using synchrotron radiation with applications in biomedical diagnosis which is currently under development. The system is designed to provide clear images and to detect contrast materials at low concentration for the quantitative functional evaluation of organs in correspondence with their anatomical structures. In this system, with x‐ray energy changing from 30 to 52 keV, images can be obtained to detect various contrast materials (iodine, barium, and gadolinium), and K‐edge energy subtraction is applied. Herein, the features of the new system designed to enhance the advantages of SR are reported. With the introduction of a double‐crystal monochromator, the high‐order x‐ray contamination is eliminated. The newly designed CCD detector with a wide dynamic range of 60 000:1 has a spatial resolution of 200 μm. The resulting image quality, which is expected to show improved contrast and spatial resolution, is currently under investigation.