论文信息 - Comparing the fixed combination dorzolamide–timolol (Cosopt®) to concomitant administration of 2% dorzolamide (Trusopt®) and 0·5% timolol – a randomized controlled trial and a replacement study

Comparing the fixed combination dorzolamide–timolol (Cosopt®) to concomitant administration of 2% dorzolamide (Trusopt®) and 0·5% timolol – a randomized controlled trial and a replacement study

Purpose: To compare the intraocular pressure (IOP) lowering effect of concomitant administration of 0·5% timolol and 2% dorzolamide and a fixed combination dorzolamide–timolol (Cosopt®). To critically evaluate discrepancies between phase 3 clinical trials and prior replacement studies.

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