First RAND-36-Item Health Survey in Three-dimensional Laparoscopy Cholecystectomy: A Prospective Randomized Study

Background/Aim: National healthcare organizers require feedback from patients to improve medical treatment methods. Three-dimensional laparoscopy cholecystectomy (3D-LC) is a modern technique in surgery. However, there are no studies with patient feedback from validated questionnaires assessing the postoperative treatment results in 3D-LC. Patients and Methods: Initially 200 patients with symptomatic cholelithiasis were randomized into 3D-LC or mini-laparotomy cholecystectomy (MC) groups. RAND-36-Item Health Survey was performed preoperatively and 4 weeks following surgery relating the survey scores between the 3D-LC and MC groups. Results: Similar postoperative RAND-36 scores were reported for both groups preoperatively and at 4 weeks following surgery, and no significant differences in RAND-36 domains were shown. When the patients in both study groups were combined, Mental Health (p<0.001), Bodily Pain (p=0.01) and General Health (p=0.016) domain scores were significantly higher, indicating a significantly positive change in quality of life 4 weeks postoperatively, while those for the Role–Physical domain were significantly lower, indicating reduced physical activity during the 4 weeks following surgery. In comparison to the Finnish reference RAND-36 scores, scores at 4 weeks were significantly higher for the Mental Health domain (MC group, p<0.001 and 3D-LC group, p=0.001) whilst scores were significantly lower in four other domains: Physical Functioning, Social Functioning, Bodily Pain and Role–Physical. Conclusion: This study shows, for the first time using the RAND-36-Item Health Survey, relatively similar short-term outcomes in patients 4 weeks following cholecystectomy by 3D-LC and MC. Although scores for three RAND-36 domains were significantly higher postoperatively, indicating a significantly positive change in quality of life, a longer follow-up after cholecystectomy is needed for final conclusions to be drawn.

[1]  Gary Alan Bass,et al.  Patient-reported outcome measures (PROMs) after laparoscopic cholecystectomy: systematic review , 2022, BJS open.

[2]  L. Kovács,et al.  Balneotherapy, a Complementary Non-pharmacological Approach for Non-Inflammatory Complaints in Systemic Lupus Erythematosus: A Pilot Study , 2022, In Vivo.

[3]  M. Eskelinen,et al.  Three-dimensional Laparoscopy (3D-LC) Versus Minilaparotomy (MC) in Cholecystectomy: A Prospective Randomized Study , 2022, In Vivo.

[4]  Hester F. Lingsma,et al.  Facilitators and barriers for implementing patient-reported outcome measures in clinical care: An academic center's initial experience. , 2021, Health policy.

[5]  H. Iijima,et al.  Factors Associated With Longitudinal QOL Change in Patients With Chronic Liver Diseases , 2021, In Vivo.

[6]  G. Calais,et al.  Neoadjuvant Treatment in Upper Rectal Cancer Does Not Improve Oncologic Outcomes But Increases Postoperative Morbidity , 2020, AntiCancer Research.

[7]  C. Divino,et al.  Assessing long term quality of life in geriatric patients after elective laparoscopic cholecystectomy. , 2020, American journal of surgery.

[8]  K. Ohba,et al.  Four-weekly Low-dose Gemcitabine and Paclitaxel in Patients With Platinum-resistant Urothelial Cancer and Performance Status 2/3 , 2019, In Vivo.

[9]  N. Yamamoto,et al.  Satisfaction After Joint-preservation Surgery in Patients With Musculoskeletal Knee Sarcoma Based on Various Scores , 2019, AntiCancer Research.

[10]  C. Krettek,et al.  Mid- to Long-term Outcomes After Split-thickness Skin Graft vs. Skin Extension by Multiple Incisions , 2019, In Vivo.

[11]  S. Fukuhara,et al.  Quality of life after single‐incision laparoscopic cholecystectomy: A randomized, clinical trial , 2019, Surgery.

[12]  C. Krettek,et al.  Clinical and Radiological Mid- to Long-term Outcomes Following Ankle Fusion , 2018, In Vivo.

[13]  Jhi-Joung Wang,et al.  Do preoperative depressive symptoms predict quality of life after laparoscopic cholecystectomy: A longitudinal prospective study , 2018, PloS one.

[14]  M. Eskelinen,et al.  Improvement in the quality of life following cholecystectomy: a randomized multicenter study of health status (RAND-36) in patients with laparoscopic cholecystectomy versus minilaparotomy cholecystectomy , 2017, Quality of Life Research.

[15]  H. Ishikawa,et al.  Carbon-ion Radiotherapy for Prostate Cancer: Analysis of Morbidities and Change in Health-related Quality of Life. , 2015, Anticancer research.

[16]  G. Chong,et al.  Comparative Study Between Total Laparoscopic and Total Robotic Radical Hysterectomy for Cervical Carcinoma: Clinical Study. , 2015, Anticancer research.

[17]  S. Schoppmann,et al.  Modern GERD treatment: feasibility of minimally invasive esophageal sphincter augmentation. , 2014, Anticancer research.

[18]  M. Eskelinen,et al.  Minilaparotomy cholecystectomy with ultrasonic dissection versus conventional laparoscopic cholecystectomy: a randomized multicenter study , 2013, Scandinavian journal of gastroenterology.

[19]  S. Sauerland,et al.  Randomized clinical trial of single‐port, minilaparoscopic and conventional laparoscopic cholecystectomy , 2013, The British journal of surgery.

[20]  J. Sehouli,et al.  Quality of life and sexuality of patients after treatment for gynaecological malignancies: results of a prospective study in 55 patients. , 2012, Anticancer research.

[21]  Jun Ma,et al.  Randomized Controlled Trial Comparing Single-Port Laparoscopic Cholecystectomy and Four-Port Laparoscopic Cholecystectomy , 2011, Annals of surgery.

[22]  Claudio Ferri,et al.  Pelvic floor rehabilitation for continence recovery after radical prostatectomy: role of a personal training re-educational program. , 2010, Anticancer research.

[23]  M. Eskelinen,et al.  Comparison of the quality of life after minilaparotomy cholecystectomy versus laparoscopic cholecystectomy: a prospective randomized study. , 2007, The Israel Medical Association journal : IMAJ.

[24]  A. Pallis,et al.  Instruments for quality of life assessment in patients with gastrointestinal cancer. , 2004, Anticancer research.

[25]  J. Monson,et al.  Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the European Association for Endoscopic Surgery , 2004, Surgical Endoscopy.

[26]  L. Morales,et al.  The RAND-36 measure of health-related quality of life , 2001, Annals of medicine.