Enhanced creative thinking under dopaminergic therapy in Parkinson disease

Creative thinking requires a combination of originality, flexibility, and usefulness. Several reports described enhanced artistic creativity in Parkinson disease (PD) patients treated with dopaminergic agents. We aimed to examine PD patients' ability to perform creativity tasks compared to healthy controls and to verify whether creativity is related to an impulse control disorder (ICD) as a complication of dopaminergic therapy.

[1]  G. Pezzoli,et al.  Artistic productivity and creative thinking in Parkinson’s disease , 2012, European journal of neurology.

[2]  D. Simonton.  Creative thought as blind-variation and selective-retention: combinatorial models of exceptional creativity. , 2010, Physics of life reviews.

[3]  Lena Hartelius,et al.  High-level language difficulties in Parkinson's disease , 2003, Clinical linguistics & phonetics.

[4]  M. Trimble,et al.  Poetic talent unmasked by treatment of Parkinson's disease , 2001, Movement disorders : official journal of the Movement Disorder Society.

[5]  J. Henry,et al.  Verbal fluency deficits in Parkinson's disease: A meta-analysis , 2004, Journal of the International Neuropsychological Society.

[6]  J. Kulisevsky,et al.  Changes in artistic style and behaviour in Parkinson’s disease: dopamine and creativity , 2009, Journal of Neurology.

[7]  A. Bonnet,et al.  [The Unified Parkinson's Disease Rating Scale]. , 2000, Revue neurologique.

[8]  N. Milgram,et al.  Creative thinking and creative performance in Israeli students. , 1976, Journal of educational psychology.

[9]  J. Joutsa,et al.  Parallel Appearance of Compulsive Behaviors and Artistic Creativity in Parkinson's Disease , 2012, Case Reports in Neurology.

[10]  A. Beck,et al.  An inventory for measuring depression. , 1961, Archives of general psychiatry.

[11]  A. Chakravarty.  The creative brain--revisiting concepts. , 2010, Medical hypotheses.

[12]  K. Boone,et al.  Functional correlates of musical and visual ability in frontotemporal dementia , 2000, British Journal of Psychiatry.

[13]  M. Hornberger,et al.  Screening for impulse control symptoms in patients with de novo Parkinson disease: A case-control study , 2013, Neurology.

[14]  B L Miller,et al.  Emergence of artistic talent in frontotemporal dementia , 1998, Neurology.

[15]  Z. Katsarou,et al.  Deductive and Inductive Reasoning in Parkinson's Disease Patients and Normal Controls: Review and Experimental Evidence , 1997, Cortex.

[16]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[17]  Rivka Inzelberg,et al.  The awakening of artistic creativity and Parkinson's disease. , 2013, Behavioral neuroscience.

[18]  Miriam Faust,et al.  Metaphors and verbal creativity: The role of the right hemisphere , 2012, Laterality.

[19]  A. Nelson,et al.  Dissociable Roles of Dopamine Within the Core and Medial Shell of the Nucleus Accumbens in Memory for Objects and Place , 2010, Behavioral neuroscience.

[20]  R. Baggott.  DISEASE , 1947, Social Policy & Administration.

[21]  M. Pell,et al.  Effects of verbal working memory deficits on metaphor comprehension in patients with Parkinson’s disease , 2007, Brain and Language.

[22]  Dean Keith Simonton.  Creative thought as blind-variation and selective-retention: combinatorial models of exceptional creativity. , 2010, Physics of life reviews.

[23]  Miriam Faust,et al.  Thinking outside the Left Box: The Role of the Right Hemisphere in Novel Metaphor Comprehension , 2012 .

[24]  Daniel Weintraub,et al.  Validation of the questionnaire for impulsive‐compulsive disorders in Parkinson's disease , 2009, Movement disorders : official journal of the Movement Disorder Society.

[25]  Daniel Weintraub,et al.  Questionnaire for impulsive‐compulsive disorders in Parkinson's Disease–Rating Scale , 2012, Movement disorders : official journal of the Movement Disorder Society.

[26]  Julien Bogousslavsky,et al.  Artistic Creativity, Style and Brain Disorders , 2005, European Neurology.

[27]  Byron Bernal,et al.  Cognitive testing toward the future: The example of Semantic Verbal Fluency (ANIMALS) , 2006 .

[28]  Diane C. Tsai.  Recent Developments in Parkinson's Disease , 1986, The Yale Journal of Biology and Medicine.

[29]  Dagmar Verbaan,et al.  The MoCA: Well-suited screen for cognitive impairment in Parkinson disease , 2011, Neurology.

[30]  A. Flaherty.  Frontotemporal and dopaminergic control of idea generation and creative drive , 2005, The Journal of comparative neurology.

[31]  K. Bhatia,et al.  Artistic profession: A potential risk factor for dopamine dysregulation syndrome in Parkinson's disease? , 2010, Movement disorders : official journal of the Movement Disorder Society.

[32]  S. Mednick.  The associative basis of the creative process. , 1962, Psychological review.

[33]  A. Chatterjee,et al.  Art Produced By a Patient with Parkinson’s Disease , 2006, Behavioural neurology.

[34]  R. Walker,et al.  Augmentation of artistic productivity in Parkinson's disease , 2006, Movement disorders : official journal of the Movement Disorder Society.

[35]  G. Schott.  Pictures as a neurological tool: lessons from enhanced and emergent artistry in brain disease. , 2012, Brain : a journal of neurology.

[36]  J. Hughes,et al.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[37]  Change in artistic expression related to subthalamic stimulation , 2006, Journal of Neurology.

[38]  M. Anheim,et al.  La créativité du patient parkinsonien , 2011 .

[39]  J. Risberg,et al.  On the neurobiology of creativity. Differences in frontal activity between high and low creative subjects , 2000, Neuropsychologia.

[40]  P. Moberg,et al.  Association of dopamine agonist use with impulse control disorders in Parkinson disease. , 2006, Archives of neurology.