JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

[1]  T. Hunter Cytokine connections , 1993, Nature.

[2]  M. Karin,et al.  Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. , 1993, Genes & development.

[3]  M. Karin,et al.  NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. , 1993, Science.

[4]  R. Davis,et al.  The mitogen-activated protein kinase signal transduction pathway. , 1993, The Journal of biological chemistry.

[5]  Y. Watanabe,et al.  A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C , 1993, Molecular and cellular biology.

[6]  R. Treisman,et al.  The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain , 1993, Cell.

[7]  E. Winter,et al.  An osmosensing signal transduction pathway in yeast. , 1993, Science.

[8]  P. Herrlich,et al.  UV‐induced activation of AP‐1 involves obligatory extranuclear steps including Raf‐1 kinase. , 1993, The EMBO journal.

[9]  H. Sadowski,et al.  Cell-free activation of a DNA-binding protein by epidermal growth factor , 1993, Nature.

[10]  M. Karin,et al.  JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. , 1993, Genes & development.

[11]  P. Herrlich,et al.  Heterodimer formation of cJun and ATF‐2 is responsible for induction of c‐jun by the 243 amino acid adenovirus E1A protein. , 1993, The EMBO journal.

[12]  J. Woodgett,et al.  Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells. , 1993, Oncogene.

[13]  M. Karin,et al.  The mammalian ultraviolet response is triggered by activation of src tyrosine kinases , 1992, Cell.

[14]  E. Krebs,et al.  The mitogen-activated protein kinase activator. , 1992, Current opinion in cell biology.

[15]  J. Avruch,et al.  Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases. , 1992, Molecular endocrinology.

[16]  T. Pawson,et al.  SH2 and SH3 domains: From structure to function , 1992, Cell.

[17]  C. Crews,et al.  The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. , 1992, Science.

[18]  R. Treisman The serum response element. , 1992, Trends in biochemical sciences.

[19]  D. Luk,et al.  Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts , 1992, Molecular and cellular biology.

[20]  J. Ferrell,et al.  Inhibition of c-Jun DNA binding by mitogen-activated protein kinase. , 1992, Molecular biology of the cell.

[21]  D. Brenner,et al.  Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity , 1992, Cell.

[22]  Tony Hunter,et al.  The regulation of transcription by phosphorylation , 1992, Cell.

[23]  M. Karin,et al.  Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73 , 1992, Molecular and cellular biology.

[24]  A. Sharrocks,et al.  Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter , 1992, Nature.

[25]  A. Kraft,et al.  Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[26]  R. Tyrrell,et al.  Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene. , 1992, Carcinogenesis.

[27]  M. Karin,et al.  Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73 , 1991, Nature.

[28]  M. Karin,et al.  The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. , 1991, Biochimica et biophysica acta.

[29]  M. Cobb,et al.  ERKs, extracellular signal-regulated MAP-2 kinases. , 1991, Current opinion in cell biology.

[30]  P. Brown,et al.  The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells , 1991, Molecular and cellular biology.

[31]  R. Davis,et al.  Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases. , 1991, The Journal of biological chemistry.

[32]  M. Molina,et al.  A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants , 1991, Molecular microbiology.

[33]  James R. Woodgett,et al.  Phosphorylation of c-jun mediated by MAP kinases , 1991, Nature.

[34]  A. Fornace,et al.  Response to adversity: molecular control of gene activation following genotoxic stress. , 1991, The New biologist.

[35]  T. Curran,et al.  Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. , 1991, The Journal of biological chemistry.

[36]  J. Avruch,et al.  pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity. , 1991, The Journal of biological chemistry.

[37]  T. Sturgill,et al.  Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6. , 1991, Biochimica et biophysica acta.

[38]  Nancy Y. Ip,et al.  ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF , 1991, Cell.

[39]  M. Karin,et al.  Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain , 1991, Nature.

[40]  M. Karin,et al.  Rapid and preferential activation of the c-jun gene during the mammalian UV response , 1991, Molecular and cellular biology.

[41]  J. Shabanowitz,et al.  Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase). , 1991, The EMBO journal.

[42]  Tony Hunter,et al.  Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity , 1991, Cell.

[43]  J. Avruch,et al.  pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine. , 1990, The Journal of biological chemistry.

[44]  C. Slaughter,et al.  An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. , 1990, Science.

[45]  G. Fink,et al.  FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation , 1990, Cell.

[46]  J. Thorner,et al.  A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae , 1989, Cell.

[47]  H. Jörnvall,et al.  Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. , 1989, The Journal of biological chemistry.

[48]  S. Ho,et al.  Site-directed mutagenesis by overlap extension using the polymerase chain reaction. , 1989, Gene.

[49]  D. Brenner,et al.  Prolonged activation of jun and collagenase genes by tumour necrosis factor-α , 1989, Nature.

[50]  Peter Angel,et al.  The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1 , 1988, Cell.

[51]  D. Smith,et al.  Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. , 1988, Gene.

[52]  H. Black POTENTIAL INVOLVEMENT OF FREE RADICAL REACTIONS IN ULTRAVIOLET LIGHT‐MEDIATED CUTANEOUS DAMAGE * , 1987, Photochemistry and photobiology.

[53]  P. Cerutti Prooxidant states and tumor promotion. , 1985, Science.

[54]  Trump Bf,et al.  INFLAMMATION AND OXIDATIVE STRESS IN CARCINOGENESIS , 1993 .

[55]  P. Herrlich,et al.  DNA damage-induced gene expression: signal transduction and relation to growth factor signaling. , 1992, Reviews of physiology, biochemistry and pharmacology.

[56]  T. Kensler,et al.  An overview of the relationship between oxidative stress and chemical carcinogenesis. , 1991, Free radical biology & medicine.

[57]  P. Vogt,et al.  jun: oncogene and transcription factor. , 1990, Advances in cancer research.

[58]  C. Bucana,et al.  The role of ultraviolet radiation in the induction of melanocytic skin tumors in inbred mice. , 1989, Cancer communications.