CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer

[1]  G. Fournet,et al.  Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer , 2020, Oncogene.

[2]  C. Menck,et al.  The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells , 2019, Scientific Reports.

[3]  Huimin Ma,et al.  Overexpression of LINC00261 inhibits non–small cell lung cancer cells progression by interacting with miR‐522‐3p and suppressing Wnt signaling , 2019, Journal of cellular biochemistry.

[4]  Yifen Zhang,et al.  Cancer-associated fibroblasts-derived IL-8 mediates resistance to cisplatin in human gastric cancer. , 2019, Cancer letters.

[5]  Martin J. Aryee,et al.  Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer , 2019, Cell.

[6]  V. Swarup,et al.  Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke , 2019, Cell.

[7]  A. Chinnaiyan,et al.  CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.

[8]  John G Doench,et al.  A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis , 2019, Nature Communications.

[9]  W. El-Rifai,et al.  Helicobacter pylori‐induced miR‐135b‐5p promotes cisplatin resistance in gastric cancer , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[10]  G. Beatty,et al.  Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance. , 2017, Molecular immunology.

[11]  Cancer-Associated Fibroblasts Contribute to PDAC Heterogeneity. , 2019, Cancer discovery.

[12]  E. Fertig,et al.  Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression. , 2019, Cancer research.

[13]  Xu Wang,et al.  Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5 , 2019, Genome Biology.

[14]  Y. Ba,et al.  Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7 , 2018, Oncogene.

[15]  J. Roh,et al.  Nrf2 inhibition reverses resistance to GPX4 inhibitor‐induced ferroptosis in head and neck cancer , 2018, Free radical biology & medicine.

[16]  A. Aplin,et al.  Arrested Developments: CDK4/6 Inhibitor Resistance and Alterations in the Tumor Immune Microenvironment , 2018, Clinical Cancer Research.

[17]  Wei Li,et al.  BAP1 links metabolic regulation of ferroptosis to tumor suppression , 2018, Nature Cell Biology.

[18]  Bo Wang,et al.  miR-522-3p Promotes Tumorigenesis in Human Colorectal Cancer via Targeting Bloom Syndrome Protein , 2018, Oncology research.

[19]  Ming Yan,et al.  Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway , 2018, Theranostics.

[20]  Kristy Brown,et al.  Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle‐ear epithelial cells , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[21]  Zhenyu Li,et al.  Ferroptosis: A Novel Anti-tumor Action for Cisplatin , 2017, Cancer research and treatment : official journal of Korean Cancer Association.

[22]  S. Jaffrey,et al.  Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 , 2018, Nature Communications.

[23]  K. Veselkov,et al.  Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression , 2017, Aging.

[24]  J. Yu,et al.  Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells1 , 2017, Neoplasia.

[25]  T. Chan,et al.  Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab , 2017, Cell.

[26]  D. Sabatini,et al.  NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis , 2017, Nature.

[27]  B. Stockwell,et al.  Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease , 2017, Cell.

[28]  D. Park,et al.  TWIST mediates resistance to paclitaxel by regulating Akt and Bcl-2 expression in gastric cancer cells , 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

[29]  Y. Ba,et al.  Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis , 2017, Nature Communications.

[30]  R. Hill,et al.  CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS , 2016, Oncogene.

[31]  W. Gu,et al.  Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses , 2016, Proceedings of the National Academy of Sciences.

[32]  D. Tang,et al.  Metallothionein‐1G facilitates sorafenib resistance through inhibition of ferroptosis , 2016, Hepatology.

[33]  Shin Yh,et al.  Upregulation of miR-522 is associated with poor outcome of hepatocellular carcinoma. , 2016 .

[34]  K. Zen,et al.  Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes , 2016, Molecules.

[35]  Eric C. Holland,et al.  The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas , 2016, Science.

[36]  B. Stockwell,et al.  Ferroptosis: Death by Lipid Peroxidation. , 2016, Trends in cell biology.

[37]  A. Carè,et al.  Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma , 2016, Journal of Translational Medicine.

[38]  C. Thompson,et al.  The Emerging Hallmarks of Cancer Metabolism. , 2016, Cell metabolism.

[39]  Y-H Shi,et al.  Upregulation of miR-522 is associated with poor outcome of hepatocellular carcinoma. , 2016, European review for medical and pharmacological sciences.

[40]  W. Gu,et al.  Ferroptosis as a p53-mediated activity during tumour suppression , 2015, Nature.

[41]  Florian Klemm,et al.  Microenvironmental regulation of therapeutic response in cancer. , 2015, Trends in cell biology.

[42]  A. Walch,et al.  Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice , 2014, Nature Cell Biology.

[43]  H. Ishwaran,et al.  Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways , 2014, Cell.

[44]  Matthew E. Welsch,et al.  Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.

[45]  Judith Campisi,et al.  Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B , 2012, Nature Medicine.

[46]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[47]  G. Bornkamm,et al.  12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases , 2010, Proceedings of the National Academy of Sciences.

[48]  Hong Yu,et al.  [Real-time quantification of microRNAs in Huh7 cells by stem-loop reverse transcriptase polymerase chain reaction]. , 2009, Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.

[49]  I. Kasman,et al.  PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. , 2009, Cancer cell.

[50]  M. Mann,et al.  MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.

[51]  N. Plesnila,et al.  Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. , 2008, Cell metabolism.

[52]  J. Lötvall,et al.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.

[53]  Alissa M. Weaver,et al.  Tumor Morphology and Phenotypic Evolution Driven by Selective Pressure from the Microenvironment , 2006, Cell.

[54]  K. Livak,et al.  Real-time quantification of microRNAs by stem–loop RT–PCR , 2005, Nucleic acids research.

[55]  Laurence Zitvogel,et al.  Exosomes: composition, biogenesis and function , 2002, Nature Reviews Immunology.