Numerical Analysis of the Die Filling Process Within a Pharmaceutical Tableting Machine

[1]  Rafael Méndez,et al.  Particle size segregation promoted by powder flow in confined space: The die filling process case , 2014 .

[2]  A. Yu,et al.  Discrete particle simulation of particulate systems: Theoretical developments , 2007 .

[3]  C. Kloss,et al.  Models, algorithms and validation for opensource DEM and CFD-DEM , 2012 .

[4]  Bruno C. Hancock,et al.  Process modeling in the pharmaceutical industry using the discrete element method. , 2009, Journal of pharmaceutical sciences.

[5]  J. van de Velde,et al.  The flow of granular solids through orifices , 1961 .

[6]  Thomson,et al.  An overview of the different excipients useful for the direct compression of tablets. , 2000, Pharmaceutical science & technology today.

[7]  Srikanth R. Gopireddy,et al.  Simulation of particle size segregation in a pharmaceutical tablet press lab-scale gravity feeder , 2017 .

[8]  William R. Ketterhagen,et al.  Simulation of powder flow in a lab-scale tablet press feed frame: Effects of design and operating parameters on measures of tablet quality , 2015 .

[9]  V. M. Puri,et al.  Methods for Minimizing Segregation: A Review , 2004 .

[10]  Luiza Dihoru,et al.  The flow of powder into simple and stepped dies , 2003 .

[11]  Rafael Méndez,et al.  Relationship between residence time distribution and forces applied by paddles on powder attrition during the die filling process , 2015 .

[12]  David A. Thompson,et al.  Experimental and numerical investigations of powder transfer , 2003 .

[13]  Srikanth R. Gopireddy,et al.  Numerical simulation of powder flow in a pharmaceutical tablet press lab-scale gravity feeder , 2016 .

[14]  N. Urbanetz,et al.  Evaluation and prediction of powder flowability in pharmaceutical tableting , 2019, Pharmaceutical development and technology.

[15]  Bruno C. Hancock,et al.  Predicting discharge dynamics from a rectangular hopper using the discrete element method (DEM) , 2008 .

[16]  Rafael Méndez,et al.  Study of the effects of feed frames on powder blend properties during the filling of tablet press dies , 2010 .

[17]  Hans J. Herrmann,et al.  Modeling granular media on the computer , 1998 .

[18]  Chris Vervaet,et al.  Reduction of tablet weight variability by optimizing paddle speed in the forced feeder of a high-speed rotary tablet press , 2015, Drug development and industrial pharmacy.

[19]  Yuichi Ozeki,et al.  Effects of powder flowability on die-fill properties in rotary compression , 2007 .