The Effects of NAM on the Symmetry of the Face and Maxillary Arch in Babies With Unilateral Cleft

The study aimed to evaluate the effect of nasoalveolar molding (NAM) therapy through reverse engineering, or its absence, to obtain symmetry of the face and maxillary arch. Twenty-six babies with unilateral cleft lip and palate received treatment with NAM, and 12 babies with unilateral cleft lip and palate without presurgical orthopedics (control group). Patients were molded and photographed in 2-stages: the first month of life (T1/pre) and after the use of NAM/before the cheiloplasty (T2/post). In the digital models, the analyses performed were arch perimeter, arch length, and labial frenulum angle. The photographs allowed us to analyze nasal width, mouth width, columella angle, and nostril area. The results demonstrated that there was an increase in arch perimeter and arch length in control and NAM groups in the T2 period in comparison to T1. Labial frenulum angle was reduced in the NAM group compared to the NAM-T1 and control-T2 periods. Treatment with NAM yielded a reduction in nasal width in the period of T2 compared with T1. Columella angle was enhanced after NAM use in T2 and, was different from control group. The nostril area was reduced in the NAM group in T2 compared with control group. Nasoalveolar molding therapy reduced the labial frenulum angle, contributing to a reduction in the extension of the cleft. The NAM protocol improved facial symmetry, mainly through nasal effects, whereas the absence of orthopedic therapy yielded a commitment to the face and maxillary arch symmetry.

[1]  Nicolas E. Sierra,et al.  Comparative Study of Maxillary Growth in Patients With Unilateral Cleft Treated With and Without Pre-Surgical Orthopedics. , 2023, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[2]  K. Patel,et al.  Long-Term Effects of Nasoalveolar Molding in Patients With Unilateral Cleft Lip and Palate: A Systematic Review and Meta-Analysis , 2021, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[3]  R. Freitas,et al.  Spontaneous Growth of the Palatal Plates in the Cleft Lip and Palate , 2020, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[4]  F. Fahim,et al.  Short-Term Efficacy of Presurgical Vacuum Formed Nasoalveolar Molding Aligners on Nose, Lip, and Maxillary Arch Morphology in Infants With Unilateral Cleft Lip and Palate: A Prospective Clinical Trial , 2020, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[5]  Li Ma,et al.  Effectiveness of presurgical orthodontics in cleft lip and palate patients with alveolar bone grafting: a systematic review. , 2020, Journal of stomatology, oral and maxillofacial surgery.

[6]  K. Bonanthaya,et al.  A Longitudinal Study of The Nasal Symmetry in Unilateral Cleft Lip And Palate Patients Treated With Nasoalveolar Molding , 2020, Indian Journal of Plastic Surgery.

[7]  Jie Zheng,et al.  A Three-Dimensional Study of the Nasolabial Soft Tissue Symmetry in Children With Unilateral Complete Cleft Lip and Palate Using Traditional and Split-Type Nasoalveolar Molding. , 2020, The Journal of craniofacial surgery.

[8]  R. Tse,et al.  Nasoalveolar Molding for Unilateral and Bilateral Cleft Lip Repair. , 2020, Oral and maxillofacial surgery clinics of North America.

[9]  M. Tayel,et al.  Early Progressive Maxillary Changes with Nasoalveolar Molding: Randomized Controlled Clinical Trial , 2019, JDR clinical and translational research.

[10]  I. Gram,et al.  Reproductive and Lifestyle Factors and Circulating sRANKL and OPG Concentrations in Women: Results from the EPIC Cohort , 2019, Cancer Epidemiology, Biomarkers & Prevention.

[11]  A. Bui,et al.  Quantitative Evaluation of Nasolabial Alterations following Nasoalveolar Molding (NAM) Therapy in Patients with Unilateral Cleft Lip , 2018, Facial Plastic Surgery.

[12]  Derya Germeç Çakan,et al.  Nasolabial Morphology Following Nasoalveolar Molding in Infants With Unilateral Cleft Lip and Palate. , 2018, The Journal of craniofacial surgery.

[13]  E. Tanaka,et al.  Effectiveness of presurgical nasoalveolar molding therapy on unilateral cleft lip nasal deformity , 2018, Saudi medical journal.

[14]  Karl C. Bruckman,et al.  The Effect of Nasoalveolar Molding on Nasal Airway Anatomy , 2018, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[15]  Jonathan M. Bekisz,et al.  A Review of Randomized Controlled Trials in Cleft and Craniofacial Surgery , 2017, The Journal of craniofacial surgery.

[16]  Jean-Marc Retrouvey,et al.  Correlation between Nasoalveolar Molding and Surgical, Aesthetic, Functional and Socioeconomic Outcomes Following Primary Repair Surgery: a Systematic Review , 2017, Journal of oral & maxillofacial research.

[17]  A. Kane,et al.  The role of Nasoalveolar molding: A 3D Prospective analysis , 2017, Scientific Reports.

[18]  E. Velasco-Ortega,et al.  Nasoalveolar Molding Therapy for the Treatment of Unilateral Cleft Lip and Palate Improves Nasal Symmetry and Maxillary Alveolar Dimensions , 2016, The Journal of craniofacial surgery.

[19]  V. Shetty,et al.  Comparison of Early Onset Nasoalveolar Molding With Patients Who Presented for Molding Up to 1 Year of Age. , 2016, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[20]  Roberto L. Flores,et al.  Surgeon’s and Caregivers’ Appraisals of Primary Cleft Lip Treatment with and without Nasoalveolar Molding: A Prospective Multicenter Pilot Study , 2016, Plastic and reconstructive surgery.

[21]  P. Dijkstra,et al.  Limited Evidence for the Effect of Presurgical Nasoalveolar Molding in Unilateral Cleft on Nasal Symmetry: A Call for Unified Research , 2013, Plastic and reconstructive surgery.

[22]  J. Meara,et al.  Nasoalveolar Molding in Cleft Care: Is It Efficacious? , 2012, Plastic and reconstructive surgery.

[23]  Aslıhan Uzel,et al.  Long-Term Effects of Presurgical Infant Orthopedics in Patients with Cleft Lip and Palate: A Systematic Review , 2011, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[24]  Gang Shen,et al.  A Novel Technique for Presurgical Nasoalveolar Molding Using Computer-Aided Reverse Engineering and Rapid Prototyping , 2011, The Journal of craniofacial surgery.

[25]  J. Little,et al.  Cleft lip and palate , 2009, The Lancet.

[26]  C. Cutting,et al.  Nasoalveolar Molding Improves Long-Term Nasal Symmetry in Complete Unilateral Cleft Lip–Cleft Palate Patients , 2009, Plastic and reconstructive surgery.

[27]  E. Ko,et al.  Symmetry of the Nose after Presurgical Nasoalveolar Molding in Infants with Unilateral Cleft Lip and Palate: A Preliminary Study , 2005, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[28]  C. A. Hood,et al.  Facial Characterization of Infants with Cleft Lip and Palate Using a Three-Dimensional Capture Technique , 2004, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[29]  R. Evans,et al.  Three-dimensional analysis of the child cleft face. , 2000, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[30]  C. Cutting,et al.  Presurgical Nasoalveolar Molding in Infants with Cleft Lip and Palate , 1999 .

[31]  F. Bookstein,et al.  Long-Term Effects of Nasoalveolar Molding on Three-Dimensional Nasal Shape in Unilateral Clefts , 1999 .

[32]  C. Cutting,et al.  Preoperative columella lengthening in bilateral cleft lip and palate. , 1993, Plastic and reconstructive surgery.

[33]  K. Matsuo,et al.  Preoperative non-surgical over-correction of cleft lip nasal deformity. , 1992, British journal of plastic surgery.

[34]  K. Matsuo,et al.  Nonsurgical Correction of Congenital Auricular Deformities in the Early Neonate: A Preliminary Report , 1984, Plastic and reconstructive surgery.

[35]  S. Macari,et al.  The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM). , 2020, Brazilian dental journal.

[36]  Vasant Radhakrishnan,et al.  Changes in maxillary alveolar morphology with nasoalveolar molding. , 2010, The Journal of clinical pediatric dentistry.