Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes.
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[1] R. Andrade,et al. Idiosyncratic drug hepatotoxicity: a 2008 update , 2008, Expert review of clinical pharmacology.
[2] Ivan Rusyn,et al. Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[3] J. Manautou,et al. Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice. , 2006, Toxicology letters.
[4] M. Thibodeau,et al. Transport deficient (TR-) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity. , 2005, Biochemical pharmacology.
[5] V. Catania,et al. Shift from Biliary to Urinary Elimination of Acetaminophen-Glucuronide in Acetaminophen-Pretreated Rats , 2005, Journal of Pharmacology and Experimental Therapeutics.
[6] P. Borst,et al. Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene , 2005, Hepatology.
[7] A. Dhawan,et al. Effects of serum from patients with acute liver failure due to paracetamol overdose on human hepatocytes in vitro. , 2005, Transplantation proceedings.
[8] R. Kurten,et al. Mechanisms of Acetaminophen-Induced Hepatotoxicity: Role of Oxidative Stress and Mitochondrial Permeability Transition in Freshly Isolated Mouse Hepatocytes , 2005, Journal of Pharmacology and Experimental Therapeutics.
[9] John A. Hunt,et al. Human Cell Culture Protocols: Isolation and Culture of Human Osteoblasts. , 2005 .
[10] Toshiharu Horie,et al. Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice. , 2005, Journal of hepatology.
[11] Melvin E Andersen,et al. Dose-dependent transitions in mechanisms of toxicity: case studies. , 2004, Toxicology and applied pharmacology.
[12] S. Higuchi,et al. Influence of Feeding Schedule on 24-h Rhythm of Hepatotoxicity Induced by Acetaminophen in Mice , 2004, Journal of Pharmacology and Experimental Therapeutics.
[13] George P Daston,et al. Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[14] Gordon Vansant,et al. Gene expression profiling of rat livers reveals indicators of potential adverse effects. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[15] E. Hazai,et al. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl)propionic acid] antagonist, is a CYP2E1 inducer. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[16] William M. Lee,et al. Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States , 2002, Annals of Internal Medicine.
[17] Thierry Lavé,et al. Influence of isolation procedure, extracellular matrix and dexamethasone on the regulation of membrane transporters gene expression in rat hepatocytes. , 2002, Biochemical pharmacology.
[18] Y. Sugiyama,et al. Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. , 2002, Drug metabolism and disposition: the biological fate of chemicals.
[19] E. Hazai,et al. Reduction of toxic metabolite formation of acetaminophen. , 2002, Biochemical and biophysical research communications.
[20] G. Hamilton,et al. Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes. , 2002, Toxicology in vitro : an international journal published in association with BIBRA.
[21] N. Vermeulen,et al. Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches , 2001, Critical reviews in toxicology.
[22] D. Keppler,et al. Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family. , 2000, Advances in enzyme regulation.
[23] Barney Ward,et al. Paracetamol revisited: A review of the pharmacokinetics and pharmacodynamics , 1999 .
[24] G. D. Johnston,et al. Paracetamol (acetaminophen) poisoning: no need to change current guidelines to accident departments , 2016 .
[25] W. Trager,et al. Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6. , 1998, Chemical research in toxicology.
[26] R. Pichlmayr,et al. Drug metabolism in hepatocyte sandwich cultures of rats and humans. , 1997, Biochemical pharmacology.
[27] D. Lamiable,et al. Metabolism and toxicity of coumarin on cultured human, rat, mouse and rabbit hepatocytes , 1996, Fundamental & clinical pharmacology.
[28] G. Jones. Human cell culture protocols , 1996 .
[29] A. Proudfoot,et al. Paracetamol (acetaminophen) poisoning , 1995, The Lancet.
[30] J. Tredger,et al. Metabolic basis for high paracetamol dosage without hepatic injury: a case study , 1995, Human & experimental toxicology.
[31] P. Thuluvath. Metabolic basis for high paracetamol dosage without hepatic injury? A case study , 1993 .
[32] F. Guengerich,et al. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. , 1993, Chemical research in toxicology.
[33] S. H. Thomas,et al. Paracetamol (acetaminophen) poisoning. , 1993, Pharmacology & therapeutics.
[34] T. Aoyama,et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. , 1992, Chemical research in toxicology.
[35] P. Beaune,et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. , 1991, Chemical research in toxicology.
[36] A. Boobis,et al. Species differences in the hepatotoxicity of paracetamol are due to differences in the rate of conversion to its cytotoxic metabolite. , 1987, Biochemical pharmacology.
[37] van der Hoeven Ta,et al. Preparation and Properties of Partially Purified Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome P-450 Reductase from Rabbit Liver Microsomes , 1974 .
[38] M. J. Coon,et al. Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. , 1974, The Journal of biological chemistry.
[39] O. H. Lowry,et al. Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.