Evaluation of Bowen disease by in vivo reflectance confocal microscopy

bility of exerting immune control over all latently EBVinfected proliferating cells. This could explain the long-term survival in our patient without exacerbation or lymphomagenesis because of the immunomodulatory role of CD4+ cell infiltration. In conclusion, the current case confirms that HV is an EBVassociated lymphoproliferative disease and that it may undergo an indolent clinical course that may be associated with CD4+ T-cell activation.

[1]  R. Webb,et al.  In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology. , 1999, The Journal of investigative dermatology.

[2]  D. Eedy,et al.  Guidelines for management of Bowen's disease: 2006 update , 2007, The British journal of dermatology.

[3]  R. Hofmann-Wellenhof,et al.  Discrimination of Actinic Keratoses from Normal Skin with Reflectance Mode Confocal Microscopy , 2008, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[4]  Salvador González,et al.  Clinical Applicability of in vivo Reflectance Confocal Microscopy for the Diagnosis of Actinic Keratoses , 2008, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[5]  R. De Angelis,et al.  The specific dermoscopical criteria of Bowen's disease , 2006, Journal of the European Academy of Dermatology and Venereology : JEADV.

[6]  R. Webb,et al.  In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. , 1995, The Journal of investigative dermatology.

[7]  Christi Alessi Fox,et al.  Reflectance confocal microscopy criteria for squamous cell carcinomas and actinic keratoses. , 2009, Archives of dermatology.

[8]  I. Zalaudek,et al.  The specific dermoscopic criteria of Bowen's disease , 2006, Journal of the European Academy of Dermatology and Venereology : JEADV.

[9]  angesichts der Corona-Pandemie,et al.  UPDATE , 1973, The Lancet.

[10]  R. Webb,et al.  Video-rate confocal scanning laser microscope for imaging human tissues in vivo. , 1999, Applied optics.

[11]  A. Weinberg,et al.  Metastatic Cutaneous Squamous Cell Carcinoma: An Update , 2007, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].