Characterisation of rapid prototyping techniques for studies in cell behaviour

Purpose – The area of microfluidic systems has greatly enhanced the in vitro field of tissue engineering. Microfluidic systems such as microchannelled assays are now widely used for mimicking in vivo cell behaviour and studies into basic biological research. In certain cases engineered tissue cell design use 3D ordered geometrical configurations in vitro (such as microchannel assays) to reproduce native in vivo functions. The most common approach for manufacturing micro‐assays is now rapid prototyping (RP) technology. The choice of assay material is dependent on the proposed cell type and ultimately the tissue application. However, many RP technologies can be unsuitable for cell growth applications because of the construction methods and materials they employ. The purpose of this paper is to describe a comparison between two different RP 3D printing methods of fabrication and investigates the merits of each technology for direct cell culture applications using micro‐assays, while also examining the dispen...

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