Effect of P2O5 on mechanical properties of porous natural hydroxyapatite derived from cortical bovine bones sintered at 1,050°C

AbstractIn the current study, the effect of P2O5 on the mechanical properties of porous natural hydroxyapatite (NHA) derived from cortical bovine bones sintered at 1,050°C is assessed. Hydroxyapatite (HA: Ca10(PO4)6(OH)2) was synthesized using several methods and manufactured from natural materials such as coral or bone after removal of the organic matter by heating (noted NHA). The in vitro and in vivo studies showed that the natural apatite was well tolerated and has better osteoconductive properties than synthetic HA. Consequently, the NHA was manufactured from cortical bovine bone in all our studies. Nevertheless, its poor mechanical properties are one of the most serious obstacles for wider applications. So, P2O5 was added into NHA in order to enhance its initially poor mechanical strength. A careful combination between the main parameters controlling NHA elaboration such as milling techniques, compacting pressure, sintering temperature, and holding time may lead to an interesting NHA-based biocerami...

[1]  A. Harabi,et al.  Shaping of microfiltration (MF) ZrO2 membranes using a centrifugal casting method , 2015 .

[2]  S. Cerneaux,et al.  Preparation of microfiltration membrane supports using coarse alumina grains coated by nano TiO2 as raw materials , 2014 .

[3]  A. Harabi,et al.  A new and economic approach to fabricate resistant porous membrane supports using kaolin and CaCO3 , 2014 .

[4]  A. Harabi,et al.  A New and Economic Approach to Synthesize and Fabricate Bioactive Diopside Ceramics Using a Modified Domestic Microwave Oven. Part 1: Study of Sintering and Bioactivity , 2014 .

[5]  A. Harabi,et al.  Reactivity kinetics of 52S4 glass in the quaternary system SiO2–CaO–Na2O–P2O5: Influence of the synthesis process: Melting versus sol–gel , 2013 .

[6]  A. Harabi,et al.  Effect of ZrO2, TiO2, and Al2O3 Additions on Process and Kinetics of Bonelike Apatite Formation on Sintered Natural Hydroxyapatite Surfaces , 2012 .

[7]  André Larbot,et al.  New clay-alumina porous capillary supports for filtration application , 2012 .

[8]  A. Harabi,et al.  Elaboration and Properties of Zirconia Microfiltration Membranes , 2012 .

[9]  A. Harabi,et al.  Production of Supports and Filtration Membranes from Algerian Kaolin and Limestone , 2012 .

[10]  A. Harabi,et al.  Preparation process of a highly resistant wollastonite bioceramics using local raw materials , 2012, Journal of Thermal Analysis and Calorimetry.

[11]  A. Harabi,et al.  Sintering and mechanical properties of porcelains prepared from algerian raw materials , 2011 .

[12]  A. Harabi,et al.  Sol-gel synthesis of a new composition of bioactive glass in the quaternary system SiO2-CaO-Na2O-P2O5 , 2011 .

[13]  G. Meng,et al.  Corrosion resistance characterization of porous alumina membrane supports , 2011 .

[14]  A. Harabi,et al.  Sintering of bioceramics using a modified domestic microwave oven , 2011 .

[15]  L. Treccani,et al.  Development and characterisation of functionalised ceramic microtubes for bacteria filtration , 2010 .

[16]  G. Meng,et al.  Recycling of fly ash for preparing porous mullite membrane supports with titania addition. , 2010, Journal of hazardous materials.

[17]  J. Bonnet,et al.  Preparation of Mullite- and Zircon-Based Ceramics Using Kaolinite and Zirconium Oxide: A Sintering Study , 2010 .

[18]  A. Harabi,et al.  Porous ceramic membranes prepared from kaolin , 2009 .

[19]  F. Bouzerara,et al.  Preparation and characterization of microfi ltration membranes and their supports using kaolin (DD2) and CaCO3 , 2009 .

[20]  A. Harabi,et al.  Preparation and characterization of tubular membrane supports using centrifugal casting , 2009 .

[21]  J. Suwanprateeb,et al.  Mechanical and in vitro performance of apatite–wollastonite glass ceramic reinforced hydroxyapatite composite fabricated by 3D-printing , 2009, Journal of materials science. Materials in medicine.

[22]  M. Usta,et al.  Hydroxyapatite and zirconia composites: Effect of MgO and MgF2 on the stability of phases and sinterability , 2008 .

[23]  S. K. Pratihar,et al.  Pressureless sintering of dense hydroxyapatite–zirconia composites , 2008, Journal of materials science. Materials in medicine.

[24]  A. Harabi,et al.  Dissolution kinetic and structural behaviour of natural hydroxyapatite vs. thermal treatment , 2008 .

[25]  L. Yahia,et al.  The effect of varying Al2O3 percentage in hydroxyapatite/Al2O3 composite materials: morphological, chemical and cytotoxic evaluation. , 2007, Journal of biomedical materials research. Part A.

[26]  S. Kim,et al.  Consolidation and mechanical properties of nanostructured hydroxyapatite–(ZrO2 + 3 mol% Y2O3) bioceramics by high-frequency induction heat sintering , 2007 .

[27]  H. Ohgushi,et al.  Fabrication of Hydroxyapatite–Zirconia Composites for Orthopedic Applications , 2006 .

[28]  A. Rapacz-Kmita,et al.  Mechanical properties of HAp–ZrO2 composites , 2006 .

[29]  A. Larbot,et al.  Porous ceramic supports for membranes prepared from kaolin and doloma mixtures , 2006 .

[30]  S. Achour,et al.  Effect of Stabilised ZrO2, Al2O3 and TiO2 on Sintering of Hydroxyapatite , 2005 .

[31]  Hyoun‐Ee Kim,et al.  Reinforcement of Hydroxyapatite Bioceramic by Addition of ZrO2 Coated with Al2O3 , 2004 .

[32]  Masakazu Kawashita,et al.  Novel bioactive materials with different mechanical properties. , 2003, Biomaterials.

[33]  Hyoun‐Ee Kim,et al.  Effect of CaF2 on densification and properties of hydroxyapatite-zirconia composites for biomedical applications. , 2002, Biomaterials.

[34]  R. R. Rao,et al.  Synthesis and sintering of hydroxyapatite–zirconia composites , 2002 .

[35]  R. Domingues,et al.  Microstructural and mechanical study of zirconia-hydroxyapatite (ZH) composite ceramics for biomedical applications , 2001 .

[36]  S. Achour,et al.  Crystallization and sintering of cordierite and anorthite based binary ceramics , 2001 .

[37]  S. Achour,et al.  A process for sintering of MgO and CaO based ceramics , 1999 .

[38]  P. Boch,et al.  Preparation of TCP–TiO2 Biocomposites and Study of Their Cytocompatibility , 1998 .

[39]  S. Barama,et al.  Processes involved during the production of Fe–W–Mo alloys by powder metallurgy , 1998 .

[40]  S. Barama,et al.  Identification of intermetallic compounds formed during sintering of the Fe--Mo--W ternary system , 1997 .

[41]  D. Bernache-Assollant,et al.  Characterization of hot pressed Al2O3-platelet reinforced hydroxyapatite composites , 1996 .

[42]  A. Harabi,et al.  Densification and grain growth in sintered alumina-chromia powder mixtures , 1995 .

[43]  A. Harabi,et al.  Mechanical properties of sintered alumina-chromia refractories , 1995 .

[44]  P. Marquis,et al.  Sintering behaviour of hydroxyapatite reinforced with 20 wt % Al2O3 , 1993, Journal of Materials Science.

[45]  Larry L. Hench,et al.  Bioceramics: From Concept to Clinic , 1991 .

[46]  Jenn–Ming Wu,et al.  Sintering of hydroxylapatite-zirconia composite materials , 1988 .