MG132 treatment attenuates cardiac remodeling and dysfunction following aortic banding in rats via the NF-κB/TGFβ1 pathway.

[1]  Yugang Dong,et al.  MG132, a proteasome inhibitor, attenuates pressure-overload-induced cardiac hypertrophy in rats by modulation of mitogen-activated protein kinase signals. , 2010, Acta biochimica et biophysica Sinica.

[2]  K. Sugano,et al.  IL-13 promotes the proliferation of rat pancreatic stellate cells through the suppression of NF-kappaB/TGF-beta1 pathway. , 2010, Biochemical and biophysical research communications.

[3]  Xuejun Wang,et al.  The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective. , 2010, Cardiovascular research.

[4]  C. Depré,et al.  The role of the ubiquitin-proteasome pathway in cardiovascular disease. , 2010, Cardiovascular research.

[5]  James D. Thomas,et al.  Speckle tracking echocardiography in the assessment of mouse models of cardiac dysfunction. , 2009, American journal of physiology. Heart and circulatory physiology.

[6]  E. Yeh,et al.  Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management. , 2009, Journal of the American College of Cardiology.

[7]  E. Moilanen,et al.  Compounds That Increase or Mimic Cyclic Adenosine Monophosphate Enhance Tristetraprolin Degradation in Lipopolysaccharide-Treated Murine J774 Macrophages , 2008, Journal of Pharmacology and Experimental Therapeutics.

[8]  M. Yacoub,et al.  Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy. , 2008, Cardiovascular research.

[9]  S. Vatner,et al.  Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload. , 2008, American journal of physiology. Heart and circulatory physiology.

[10]  G. Baumann,et al.  Suppression of Cardiomyocyte Hypertrophy by Inhibition of the Ubiquitin-Proteasome System , 2008, Hypertension.

[11]  Li Chen,et al.  The inhibition of TNF-α-induced E-selectin expression in endothelial cells via the JNK/NF-κB pathways by highly N-acetylated chitooligosaccharides , 2007 .

[12]  S. Vatner,et al.  Activation of the Cardiac Proteasome During Pressure Overload Promotes Ventricular Hypertrophy , 2006, Circulation.

[13]  R. Austin,et al.  Proteasomal regulation of cardiac hypertrophy: is demolition necessary for building? , 2006, Circulation.

[14]  M. Knox,et al.  Effect of flywheel-based resistance exercise on processes contributing to muscle atrophy during unloading in adult rats. , 2006, Journal of applied physiology.

[15]  G. Warren,et al.  Selectively enhanced radiation sensitivity in prostate cancer cells associated with proteasome inhibition. , 2006, Oncology reports.

[16]  M. Hori,et al.  Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice. , 2006, Biochemical and biophysical research communications.

[17]  C. Depré,et al.  Protein turnover in cardiac cell growth and survival. , 2005, Cardiovascular research.

[18]  M. Tisdale,et al.  Angiotensin II directly induces muscle protein catabolism through the ubiquitin–proteasome proteolytic pathway and may play a role in cancer cachexia , 2005, British Journal of Cancer.

[19]  N. Rosenthal,et al.  Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. , 2005, The Journal of clinical investigation.

[20]  M. Laule,et al.  Downregulation of Matrix Metalloproteinases and Collagens and Suppression of Cardiac Fibrosis by Inhibition of the Proteasome , 2004, Hypertension.

[21]  Zhao-long Wu,et al.  NF-kappa B involved in transcription enhancement of TGF-beta 1 induced by Ox-LDL in rat mesangial cells. , 2004, Chinese medical journal.

[22]  P. Kloetzel,et al.  Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes* , 2003, Journal of Biological Chemistry.

[23]  J. Schaper,et al.  Progression From Compensated Hypertrophy to Failure in the Pressure-Overloaded Human Heart: Structural Deterioration and Compensatory Mechanisms , 2003, Circulation.

[24]  Michael J Dunn,et al.  Hyperubiquitination of proteins in dilated cardiomyopathy , 2003, Proteomics.

[25]  B. Hinz,et al.  Myofibroblasts and mechano-regulation of connective tissue remodelling , 2002, Nature Reviews Molecular Cell Biology.

[26]  D. Thuerauf,et al.  p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. , 2000, The Journal of biological chemistry.

[27]  Y. Sun,et al.  Local angiotensin II and transforming growth factor-beta1 in renal fibrosis of rats. , 2000, Hypertension.

[28]  A. Asai,et al.  Proteasome Inhibitors Induce Cytochrome c–Caspase-3-Like Protease-Mediated Apoptosis in Cultured Cortical Neurons , 2000, The Journal of Neuroscience.

[29]  G. Owens,et al.  Similarities and Differences in Smooth Muscle α-Actin Induction by TGF-β in Smooth Muscle Versus Non–Smooth Muscle Cells , 1999 .

[30]  Keiji Tanaka,et al.  4-Hydroxy-2-nonenal-mediated Impairment of Intracellular Proteolysis during Oxidative Stress , 1999, The Journal of Biological Chemistry.

[31]  A. Borczuk,et al.  β-Adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy. , 1998, American journal of physiology. Heart and circulatory physiology.

[32]  Matthias Mann,et al.  IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .

[33]  A. A. Lee,et al.  Adenovirus-mediated overexpression of human transforming growth factor-beta 1 in rat cardiac fibroblasts, myocytes and smooth muscle cells. , 1996, Journal of molecular and cellular cardiology.

[34]  K. Weber,et al.  Myocardial fibrosis in hypertensive heart disease: an overview of potential regulatory mechanisms. , 1995, European heart journal.

[35]  Tom Maniatis,et al.  The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB , 1994, Cell.

[36]  S. Silver,et al.  Heart Failure , 1937, The New England journal of medicine.

[37]  M. McGuinness,et al.  NF-κB as an integrator of diverse signaling pathways , 2007, Cardiovascular Toxicology.

[38]  A. Zanchetti,et al.  Hypertensive myocardial fibrosis. , 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[39]  The Transforming Growth Factor- (cid:1) /Smad3 Pathway Coming of Age as a Key Participant in Cardiac Remodeling , 2022 .