Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment.

[1]  Anthony Atala,et al.  Methods Of Tissue Engineering , 2006 .

[2]  A. M. Parfitt,et al.  Age-related structural changes in trabecular and cortical bone: Cellular mechanisms and biomechanical consequences , 2006, Calcified Tissue International.

[3]  G. Sukhikh,et al.  Mesenchymal Stem Cells , 2002, Bulletin of Experimental Biology and Medicine.

[4]  G. Whitesides,et al.  Cell shape provides global control of focal adhesion assembly. , 2003, Biochemical and biophysical research communications.

[5]  J. Hancock,et al.  Ras proteins: different signals from different locations , 2003, Nature Reviews Molecular Cell Biology.

[6]  J. Settleman,et al.  Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis , 2003, Cell.

[7]  Christopher S. Chen,et al.  Cells lying on a bed of microneedles: An approach to isolate mechanical force , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[8]  L. Fajas.  Adipogenesis: a cross-talk between cell proliferation and cell differentiation , 2003, Annals of medicine.

[9]  A. Hall,et al.  Rho GTPases in cell biology , 2002, Nature.

[10]  A. Blangy,et al.  N-cadherin–dependent cell–cell contact regulates Rho GTPases and β-catenin localization in mouse C2C12 myoblasts , 2002, The Journal of cell biology.

[11]  E. Sahai,et al.  ROCK and Dia have opposing effects on adherens junctions downstream of Rho , 2002, Nature Cell Biology.

[12]  Celeste M Nelson,et al.  Cell‐cell signaling by direct contact increases cell proliferation via a PI3K‐dependent signal , 2002, FEBS letters.

[13]  Kevin E. Healy,et al.  Engineering gene expression and protein synthesis by modulation of nuclear shape , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Christopher S. Chen,et al.  Microcontact Printing of Proteins on Mixed Self-Assembled Monolayers , 2002 .

[15]  A. Altman,et al.  Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells , 2001, The Journal of cell biology.

[16]  V. Sikavitsas,et al.  Biomaterials and bone mechanotransduction. , 2001, Biomaterials.

[17]  Benjamin Geiger,et al.  Focal Contacts as Mechanosensors Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an Mdia1-Dependent and Rock-Independent Mechanism , 2001 .

[18]  L. Addadi,et al.  Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates , 2001, Nature Cell Biology.

[19]  W. Telford,et al.  Detection of endogenous and antibody-conjugated alkaline phosphatase with ELF-97 phosphate in multicolor flow cytometry applications. , 2001, Cytometry.

[20]  N. Balaban,et al.  Force and focal adhesion assembly , 2001 .

[21]  S. Narumiya,et al.  Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. , 2000, Molecular pharmacology.

[22]  M. Pittenger,et al.  Adult Human Mesenchymal Stem Cell Differentiation to the Osteogenic or Adipogenic Lineage Is Regulated by Mitogen-activated Protein Kinase* , 2000, The Journal of Biological Chemistry.

[23]  M. Schwartz,et al.  Determination of GTP loading on Rho. , 2000, Methods in enzymology.

[24]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[25]  W. Kiosses,et al.  Regulation of the small GTP‐binding protein Rho by cell adhesion and the cytoskeleton , 1999, The EMBO journal.

[26]  R. Franceschi,et al.  The developmental control of osteoblast-specific gene expression: role of specific transcription factors and the extracellular matrix environment. , 1999, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[27]  D. Burr,et al.  Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions. , 1998, American journal of physiology. Cell physiology.

[28]  R. Schwartz,et al.  RhoA Signaling via Serum Response Factor Plays an Obligatory Role in Myogenic Differentiation* , 1998, The Journal of Biological Chemistry.

[29]  C. S. Chen,et al.  Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. , 1998, Molecular biology of the cell.

[30]  L. Gerstenfeld,et al.  Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation , 1998, Journal of cellular biochemistry.

[31]  M. Primig,et al.  RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts. , 1998, Molecular biology of the cell.

[32]  Y. Hiroi,et al.  The Rho Family G Proteins Play a Critical Role in Muscle Differentiation , 1998, Molecular and Cellular Biology.

[33]  H. Sul,et al.  Understanding adipocyte differentiation. , 1998, Physiological reviews.

[34]  高野博之.  The Rho Family G proteins Play a Critical Role in Muscle Differentiation(低分子量G蛋白質Rhoファミリーの筋分化における役割) , 1998 .

[35]  M. Gray,et al.  Signal Transduction of Mechanical Stimuli Is Dependent on Microfilament Integrity: Identification of Osteopontin as a Mechanically Induced Gene in Osteoblasts , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[36]  M. Lazar,et al.  Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte Differentiation* , 1997, The Journal of Biological Chemistry.

[37]  C. S. Chen,et al.  Geometric control of cell life and death. , 1997, Science.

[38]  H. Sul,et al.  Molecular mechanisms of adipocyte differentiation and inhibitory action of pref-1. , 1997, Critical reviews in eukaryotic gene expression.

[39]  I. Vuori.  Peak bone mass and physical activity: a short review. , 2009, Nutrition reviews.

[40]  Kozo Kaibuchi,et al.  Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase) , 1996, Science.

[41]  K. Burridge,et al.  Rho-stimulated contractility drives the formation of stress fibers and focal adhesions , 1996, The Journal of cell biology.

[42]  B. Gumbiner,et al.  Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis , 1996, Cell.

[43]  B. Spiegelman,et al.  Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[44]  R. Treisman,et al.  The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF , 1995, Cell.

[45]  M J Bissell,et al.  Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[46]  C J Marshall,et al.  Post-translational modifications of p21rho proteins. , 1992, The Journal of biological chemistry.

[47]  C. Stevens,et al.  Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis , 2021, Nature Reviews Neuroscience.

[48]  A. Ben-Ze'ev,et al.  Regulation of fibronectin, integrin and cytoskeleton expression in differentiating adipocytes: inhibition by extracellular matrix and polylysine. , 1989, Differentiation; research in biological diversity.

[49]  F. Watt,et al.  Cell shape controls terminal differentiation of human epidermal keratinocytes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[50]  J. Aubin,et al.  Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone , 1988, The Journal of cell biology.

[51]  B. Spiegelman,et al.  Fibronectin modulation of cell shape and lipogenic gene expression in 3t3-adipocytes , 1983, Cell.

[52]  A. Friedenstein.  Precursor cells of mechanocytes. , 1976, International review of cytology.

[53]  H. Green,et al.  Sublines of mouse 3T3 cells that accumulate lipid , 1974 .

[54]  D'arcy W. Thompson.  On Growth and Form , 1917, Nature.

[55]  J. Wolff.  Das Gesetz der Transformation der Knochen , 1893 .