Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours

[1]  A. George,et al.  Delivery of oligodeoxynucleotides into human saphenous veins and the adjunct effect of ultrasound and microbubbles. , 2005, Ultrasound in medicine & biology.

[2]  Abhrajyoti Ghosh Different approaches of gene therapy used in prostate cancer. , 2005, Cellular and Molecular Biology.

[3]  K. Itoh,et al.  The Effects of Levovist and DD‐723 in Activating Platelets and Damaging Hepatic Cells of Rats , 2005, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[4]  V. Oberle,et al.  Efficient transfer of chromosome-based DNA constructs into mammalian cells. , 2004, Biochimica et biophysica acta.

[5]  R. Vessella,et al.  Molecular determinants of resistance to antiandrogen therapy , 2004, Nature Medicine.

[6]  Sanjiv Kaul,et al.  Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles. , 2003, Ultrasound in medicine & biology.

[7]  K. Hynynen,et al.  Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery , 2003, Gene Therapy.

[8]  Raffi Bekeredjian,et al.  Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasound-targeted microbubble destruction. , 2003, Journal of the American College of Cardiology.

[9]  Chawnshang Chang,et al.  Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. , 2003, Biochemical and biophysical research communications.

[10]  G. Freeman,et al.  Ultrasound-targeted antisense oligonucleotide attenuates ischemia/reperfusion-induced myocardial tumor necrosis factor-alpha. , 2003, Journal of molecular and cellular cardiology.

[11]  K. Tachibana,et al.  In vitro transfer of antisense oligodeoxynucleotides into coronary endothelial cells by ultrasound. , 2002, Biochemical and biophysical research communications.

[12]  H. Klocker,et al.  Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor , 2002, Cancer Gene Therapy.

[13]  J. Isner Myocardial gene therapy , 2002, Nature.

[14]  G. Bartsch,et al.  Detection of prostate cancer with a microbubble ultrasound contrast agent , 2001, The Lancet.

[15]  E. Unger,et al.  Gene Delivery Using Ultrasound Contrast Agents , 2001, Echocardiography.

[16]  K. Anwer,et al.  Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration , 2000, Gene Therapy.

[17]  H. Klocker,et al.  Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides , 2000, Cancer Gene Therapy.

[18]  Donna M. Peehl,et al.  Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor , 2000, Nature Medicine.

[19]  D. Peehl,et al.  Erratum: Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor (Nature Medicine (2000) 6 (703-706)) , 2000 .

[20]  P. Huber,et al.  In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound , 2000, Gene Therapy.

[21]  Martin R. Schneider,et al.  Switch from antagonist to agonist of the androgen receptor blocker bicalutamide is associated with prostate tumour progression in a new model system , 1999, British Journal of Cancer.

[22]  T C Skalak,et al.  Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. , 1998, Circulation.

[23]  P. Nelson,et al.  Dynamically stabilized pores in bilayer membranes. , 1996, Biophysical journal.

[24]  Douglas L. Miller,et al.  Transfection of a reporter plasmid into cultured cells by sonoporation in vitro. , 1997, Ultrasound in medicine & biology.

[25]  H. Klocker,et al.  Regulation of prostatic growth and function by peptide growth factors , 1996, The Prostate.

[26]  H. Klocker,et al.  Androgen receptor status of lymph node metastases from prostate cancer , 1996, The Prostate.

[27]  H. Klocker,et al.  Distant metastases from prostatic carcinoma express androgen receptor protein. , 1995, Cancer research.

[28]  H. Klocker,et al.  Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor. , 1995, European urology.

[29]  H. Klocker,et al.  Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. , 1993, Molecular endocrinology.

[30]  T. H. van der Kwast,et al.  Hormone-induced dissociation of the androgen receptor-heat-shock protein complex: use of a new monoclonal antibody to distinguish transformed from nontransformed receptors. , 1992, Biochemistry.

[31]  T. H. van der Kwast,et al.  Androgen receptors in endocrine‐therapy‐resistant human prostate cancer , 1991, International journal of cancer.

[32]  G. Jenster,et al.  A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. , 1990, Biochemical and biophysical research communications.

[33]  N. Kyprianou,et al.  Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. , 1990, Cancer research.

[34]  A. V. von Eschenbach,et al.  Hormonal therapy for prostate cancer. , 1990, Seminars in surgical oncology.