Chromatographic analysis of the enantiomers of ifosfamide and some of its metabolites in plasma and urine.

[1]  P. Houghton,et al.  Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice. , 1990, Cancer research.

[2]  J. M. Reid,et al.  Liquid chromatographic determination of cyclophosphamide enantiomers in plasma by precolumn chiral derivatization. , 1989, Analytical chemistry.

[3]  G. Blaschke Chromatographic Resolution of Chiral Drugs on Polyamides and Cellulose Triacetate , 1986 .

[4]  M. Varini,et al.  Ifosfamide--pharmacology, safety and therapeutic potential. , 1985, Cancer treatment reviews.

[5]  W. Stec,et al.  Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine. , 1983, Journal of medicinal chemistry.

[6]  M. H. Baker,et al.  Quantification by gas chromatography of N,N'-di-(2-chloroethyl)-phosphorodiamidic acid in the plasma of patients receiving isophosphamide. , 1980, Cancer research.

[7]  W. Stec,et al.  Synthesis and absolute configuration assignments of enantiomeric forms of ifosphamide, sulfosphamide, and trofosphamide , 1979 .

[8]  W. Stec,et al.  Comparative metabolism of 2-[bis(2-chloroethyl)amino]tetrahydro-2-H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide) and its enantiomers in humans. , 1979, Cancer research.

[9]  W. Stec,et al.  Stereoselectivity in the metabolism of the enantiomers of cyclophosphamide in mice, rats, and rabbits. , 1978, Drug metabolism and disposition: the biological fate of chemicals.

[10]  P. Farmer,et al.  Observations on the differential metabolism and biological activity of the optical isomers of cyclophosphamide. , 1976, Biochemical pharmacology.

[11]  I. Wainer,et al.  The determination of (-)-(S)- and (+)-(R)-ifosfamide in plasma using enantioselective gas chromatography: a validated assay for pharmacokinetic and clinical studies. , 1989, Chirality.

[12]  P. Farmer Enantiomers of cyclophosphamide and iphosphamide. , 1988, Biochemical pharmacology.

[13]  G. Blaschke,et al.  Chromatographic resolutions. XIV. Optical resolution of the racemic anticancer drug ifosfamide and other chiral oxazaphosphorines. , 1986, Journal of chromatography.