Dimensional analysis of HRV in hypertrophic cardiomyopathy patients.

Hypertrophic cardiomyopathy (HCM) is an excessive thickening of the heart muscle in the absence of an apparent cause. This condition excludes individuals with high blood pressure or prolonged athletic training. It is characterized by left and/or right ventricular hypertrophy, which is usually asymmetric. It is a familial disease with autosomal dominant inheritance caused by mutations in the sarcomeric contractile protein gene [1]. The electrocardiogram (ECG) of those patients who have this pathology shows an abnormal electric signal due to the thickening of the heart and the loss of the normal alignment of heart muscle cells. Some H CM patients c an d evelop arrhythmias (ventricular tachycardia and atrial fibrillation), endocarditis, heart block, and also sudden cardiac death (SCD). In HCM patients there is an increased risk of premature death, which can occur with little or no warning. SCD can strike at any age [2]. However, stratification for sudden cardiac death on patients with HCM is highly difficult [3].

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