Glucocorticoid-induced leucine zipper modulates macrophage polarization and apoptotic cell clearance.

[1]  M. Teixeira,et al.  Cyclic AMP Regulates Key Features of Macrophages via PKA: Recruitment, Reprogramming and Efferocytosis , 2020, Cells.

[2]  D. Annane,et al.  Overexpression of GILZ in macrophages limits systemic inflammation while increasing bacterial clearance in sepsis in mice , 2019, European journal of immunology.

[3]  J. Decruyenaere,et al.  Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis. , 2019, Shock.

[4]  M. Perretti,et al.  Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes , 2019, Front. Immunol..

[5]  M. Perretti,et al.  Mediators of the Resolution of the Inflammatory Response. , 2019, Trends in immunology.

[6]  C. Riccardi,et al.  Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages , 2019, Front. Immunol..

[7]  M. Pellegrini,et al.  Plasticity of antimicrobial and phagocytic programs in human macrophages , 2018, Immunology.

[8]  C. Riccardi,et al.  GILZ restrains neutrophil activation by inhibiting the MAPK pathway , 2018, Journal of leukocyte biology.

[9]  B. Baban,et al.  Glucocorticoid-Induced Leucine Zipper Promotes Neutrophil and T-Cell Polarization with Protective Effects in Acute Kidney Injury , 2018, The Journal of Pharmacology and Experimental Therapeutics.

[10]  M. Teixeira,et al.  Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1. , 2017, Blood.

[11]  C. Riccardi,et al.  Role of the glucocorticoid‐induced leucine zipper gene in dexamethasone‐induced inhibition of mouse neutrophil migration via control of annexin A1 expression , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[12]  Michael R. Elliott,et al.  Efferocytosis Signaling in the Regulation of Macrophage Inflammatory Responses , 2017, The Journal of Immunology.

[13]  E. Morand,et al.  Glucocorticoid-Induced Leucine Zipper Protein Controls Macropinocytosis in Dendritic Cells , 2016, The Journal of Immunology.

[14]  C. Riccardi,et al.  Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages* , 2016, The Journal of Biological Chemistry.

[15]  Mallary C Greenlee-Wacker,et al.  Clearance of apoptotic neutrophils and resolution of inflammation , 2016, Immunological reviews.

[16]  Mauro M. Teixeira,et al.  Resolution of Inflammation: What Controls Its Onset? , 2016, Front. Immunol..

[17]  E. Morand,et al.  Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus , 2015, Annals of the rheumatic diseases.

[18]  C. Riccardi,et al.  GILZ as a Mediator of the Anti-Inflammatory Effects of Glucocorticoids , 2015, Front. Endocrinol..

[19]  E. Mazzon,et al.  Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice. , 2015, Blood.

[20]  M. Pallardy,et al.  Glucocorticoid-Induced Leucine Zipper Is Expressed in Human Neutrophils and Promotes Apoptosis through Mcl-1 Down-Regulation , 2015, Journal of Innate Immunity.

[21]  E. Morand,et al.  GILZ regulates Th17 responses and restrains IL-17-mediated skin inflammation. , 2015, Journal of autoimmunity.

[22]  C. Riccardi,et al.  Glucocorticoid-Induced Leucine Zipper: A Critical Factor in Macrophage Endotoxin Tolerance , 2015, The Journal of Immunology.

[23]  C. Riccardi,et al.  The Role and Effects of Glucocorticoid-Induced Leucine Zipper in the Context of Inflammation Resolution , 2015, The Journal of Immunology.

[24]  G. Fingerle-Rowson,et al.  Macrophage Migration Inhibitory Factor Inhibits the Antiinflammatory Effects of Glucocorticoids via Glucocorticoid‐Induced Leucine Zipper , 2014, Arthritis & rheumatology.

[25]  S. Goerdt,et al.  Macrophage activation and polarization: nomenclature and experimental guidelines. , 2014, Immunity.

[26]  C. Riccardi,et al.  GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling. , 2014, Cell reports.

[27]  S. Behar,et al.  Macrophages clean up: efferocytosis and microbial control. , 2014, Current opinion in microbiology.

[28]  J. Duffield,et al.  Changes in macrophage phenotype as the immune response evolves. , 2013, Current opinion in pharmacology.

[29]  M. Teixeira,et al.  Pharmacological strategies to resolve acute inflammation. , 2013, Current opinion in pharmacology.

[30]  M. Teixeira,et al.  Resolution of inflammation: mechanisms and opportunity for drug development. , 2013, Pharmacology & therapeutics.

[31]  Xuelin Huang,et al.  An improvement of the 2ˆ(-delta delta CT) method for quantitative real-time polymerase chain reaction data analysis. , 2013, Biostatistics, bioinformatics and biomathematics.

[32]  M. Lionakis,et al.  Isolation, purification and labeling of mouse bone marrow neutrophils for functional studies and adoptive transfer experiments. , 2013, Journal of visualized experiments : JoVE.

[33]  M. Hickey,et al.  GILZ Overexpression Inhibits Endothelial Cell Adhesive Function through Regulation of NF-κB and MAPK Activity , 2013, The Journal of Immunology.

[34]  E. Morand,et al.  Divergent effects of endogenous and exogenous glucocorticoid-induced leucine zipper in animal models of inflammation and arthritis. , 2013, Arthritis and rheumatism.

[35]  C. Libert,et al.  LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome , 2013, EMBO molecular medicine.

[36]  A. Sica,et al.  Macrophage plasticity and polarization in tissue repair and remodelling , 2013, The Journal of pathology.

[37]  C. Serhan,et al.  Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. , 2012, Blood.

[38]  M. Teixeira,et al.  Annexin A1 modulates natural and glucocorticoid‐induced resolution of inflammation by enhancing neutrophil apoptosis , 2012, Journal of leukocyte biology.

[39]  B. Brüne,et al.  Glucocorticoid‐induced leucine zipper is downregulated in human alveolar macrophages upon Toll‐like receptor activation , 2012, European journal of immunology.

[40]  D. Good,et al.  Toll-like Receptor 2 Is Required for LPS-induced Toll-like Receptor 4 Signaling and Inhibition of Ion Transport in Renal Thick Ascending Limb* , 2012, The Journal of Biological Chemistry.

[41]  Alberto Mantovani,et al.  Macrophage plasticity and polarization: in vivo veritas. , 2012, The Journal of clinical investigation.

[42]  C. Serhan,et al.  New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation , 2012, Front. Immun..

[43]  E. Mazzon,et al.  Glucocorticoid-Induced Leucine Zipper (GILZ) Over-Expression in T Lymphocytes Inhibits Inflammation and Tissue Damage in Spinal Cord Injury , 2011, Neurotherapeutics.

[44]  M. Srinivasan,et al.  Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis , 2011, The Journal of Biological Chemistry.

[45]  E. Morand,et al.  Role of GILZ in immune regulation, glucocorticoid actions and rheumatoid arthritis , 2011, Nature Reviews Rheumatology.

[46]  C. Serhan,et al.  Saturated‐efferocytosis generates pro‐resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids , 2011, European journal of immunology.

[47]  D. Scherman,et al.  Glucocorticoid-induced leucine zipper is an endogenous antiinflammatory mediator in arthritis. , 2010, Arthritis and rheumatism.

[48]  C. A. Bonjardim,et al.  PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA‐PI3K/Akt‐dependent and NF‐κB‐independent manner , 2010, Journal of leukocyte biology.

[49]  R. Medzhitov Inflammation 2010: New Adventures of an Old Flame , 2010, Cell.

[50]  C. Riccardi,et al.  Glucocorticoid‐induced leucine zipper (GILZ): a new important mediator of glucocorticoid action , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[51]  C. A. Bonjardim,et al.  Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB. , 2009, Biochemical pharmacology.

[52]  E. Morand,et al.  Annexin-1 Regulates Macrophage IL-6 and TNF via Glucocorticoid-Induced Leucine Zipper1 , 2009, The Journal of Immunology.

[53]  I. Megson,et al.  Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro‐inflammatory and anti‐inflammatory agents: key role for TNF‐α , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[54]  E. Mazzon,et al.  Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. , 2009, Gastroenterology.

[55]  J. Wallace,et al.  Resolution of in flammation: state of the art, definitions and terms , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[56]  C. Riccardi,et al.  Decrease of Bcl-xL and augmentation of thymocyte apoptosis in GILZ overexpressing transgenic mice. , 2004, Blood.

[57]  Silvano Sozzani,et al.  The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.

[58]  A. Foussat,et al.  Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. , 2003, Blood.

[59]  J. Ashwell,et al.  Inhibition of AP-1 by the Glucocorticoid-inducible Protein GILZ* , 2001, The Journal of Biological Chemistry.

[60]  C. Riccardi,et al.  Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. , 2001, Blood.

[61]  C. Riccardi,et al.  Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene , 2001, Cell Death and Differentiation.