The Hepatocyte as a Household for Plasmodium Parasites

[1]  Elizabeth K. K. Glennon,et al.  Opportunities for Host-targeted Therapies for Malaria. , 2018, Trends in parasitology.

[2]  Anne-Claire Langlois,et al.  Plasmodium sporozoites can invade hepatocytic cells independently of the Ephrin receptor A2 , 2018, PloS one.

[3]  M. Mota,et al.  Parasite Sensing of Host Nutrients and Environmental Cues. , 2018, Cell host & microbe.

[4]  Vincent L. Butty,et al.  In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites. , 2018, Cell host & microbe.

[5]  M. Mota,et al.  Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes , 2017, Nature Microbiology.

[6]  M. Mota,et al.  Dietary alterations modulate susceptibility to Plasmodium infection , 2017, Nature Microbiology.

[7]  K. Heiss,et al.  The Plasmodium liver-stage parasitophorous vacuole: A front-line of communication between parasite and host. , 2017, International journal of medical microbiology : IJMM.

[8]  Rita I Aroeira,et al.  Uptake and metabolism of arginine impact Plasmodium development in the liver , 2017, Scientific Reports.

[9]  J. Guan,et al.  LC3‐association with the parasitophorous vacuole membrane of Plasmodium berghei liver stages follows a noncanonical autophagy pathway , 2017, Cellular microbiology.

[10]  C. Andolina,et al.  Plasmodium P36 determines host cell receptor usage during sporozoite invasion , 2017, eLife.

[11]  S. Bhatia,et al.  Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers , 2017, Scientific Reports.

[12]  M. Mota,et al.  Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development , 2017, Proceedings of the National Academy of Sciences.

[13]  H. Staines,et al.  GLUT1‐mediated glucose uptake plays a crucial role during Plasmodium hepatic infection , 2016, Cellular microbiology.

[14]  S. Bhatia,et al.  Host AMPK Is a Modulator of Plasmodium Liver Infection , 2016, Cell reports.

[15]  C. Janse,et al.  Multidrug ATP‐binding cassette transporters are essential for hepatic development of Plasmodium sporozoites , 2016, Cellular microbiology.

[16]  Laura Cabrita-Santos,et al.  Host cell autophagy contributes to Plasmodium liver development , 2016, Cellular microbiology.

[17]  M. Mota,et al.  A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium , 2016, Nature Communications.

[18]  S. Kappe,et al.  Malaria parasites target the hepatocyte receptor EphA2 for successful host infection , 2015, Science.

[19]  M. Mota,et al.  Unveiling the pathogen behind the vacuole , 2015, Nature Reviews Microbiology.

[20]  M. Mann,et al.  Parasite‐induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection , 2015, EMBO reports.

[21]  S. Kappe,et al.  Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites. , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

[22]  A. Vaughan,et al.  Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice. , 2015, Cell host & microbe.

[23]  Sangeeta N. Bhatia,et al.  Human iPSC-Derived Hepatocyte-like Cells Support Plasmodium Liver-Stage Infection In Vitro , 2015, Stem cell reports.

[24]  A. Shevchenko,et al.  Host Cell Phosphatidylcholine Is a Key Mediator of Malaria Parasite Survival during Liver Stage Infection , 2014, Cell host & microbe.

[25]  Laura Cabrita-Santos,et al.  Host PI(3,5)P2 Activity Is Required for Plasmodium berghei Growth During Liver Stage Infection , 2014, Traffic.

[26]  P. Baldacci,et al.  ZIPCO, a putative metal ion transporter, is crucial for Plasmodium liver-stage development , 2014, EMBO molecular medicine.

[27]  M. Mota,et al.  Malaria infections: what and how can mice teach us. , 2014, Journal of immunological methods.

[28]  A. Vaughan,et al.  Interferon-mediated innate immune responses against malaria parasite liver stages. , 2014, Cell Reports.

[29]  G. Superti-Furga,et al.  Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection , 2013, Nature Medicine.

[30]  Mario Roederer,et al.  Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine , 2013, Science.

[31]  S. Kappe,et al.  Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis , 2013, Cell Death and Disease.

[32]  M. Mota,et al.  Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins , 2013, Proceedings of the National Academy of Sciences.

[33]  Anne E Carpenter,et al.  A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. , 2013, Cell host & microbe.

[34]  Kevin Marsh,et al.  Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure. , 2013, The New England journal of medicine.

[35]  M. Assfalg,et al.  Evidence from NMR interaction studies challenges the hypothesis of direct lipid transfer from L‐FABP to malaria sporozoite protein UIS3 , 2013, Protein science : a publication of the Protein Society.

[36]  S. Kappe,et al.  Extrahepatic Exoerythrocytic Forms of Rodent Malaria Parasites at the Site of Inoculation: Clearance after Immunization, Susceptibility to Primaquine, and Contribution to Blood-Stage Infection , 2012, Infection and Immunity.

[37]  V. Heussler,et al.  Mitochondrial lipoic acid scavenging is essential for Plasmodium berghei liver stage development , 2012, Cellular microbiology.

[38]  F. Frischknecht,et al.  Highly Dynamic Host Actin Reorganization around Developing Plasmodium Inside Hepatocytes , 2012, PloS one.

[39]  M. Mota,et al.  A toolbox to study liver stage malaria. , 2011, Trends in parasitology.

[40]  C. Newbold,et al.  Host-mediated regulation of superinfection in malaria , 2011, Nature Medicine.

[41]  I. Coppens,et al.  Plasmodium salvages cholesterol internalized by LDL and synthesized de novo in the liver , 2011, Cellular microbiology.

[42]  M. Mota,et al.  Use of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle , 2011, Antimicrobial Agents and Chemotherapy.

[43]  S. Thiberge,et al.  Development of the malaria parasite in the skin of the mammalian host , 2010, Proceedings of the National Academy of Sciences.

[44]  A. Vaughan,et al.  Genetically engineered, attenuated whole-cell vaccine approaches for malaria , 2010, Human vaccines.

[45]  P. Sinnis,et al.  Plasmodium sporozoite-host interactions from the dermis to the hepatocyte. , 2009, Current opinion in microbiology.

[46]  D. Morrison Evolution of the Apicomplexa: where are we now? , 2009, Trends in parasitology.

[47]  M. Mota,et al.  Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells , 2009, Cellular microbiology.

[48]  Xinxia Peng,et al.  Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events , 2009, BMC Genomics.

[49]  C. Echeverri,et al.  Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. , 2008, Cell host & microbe.

[50]  Daniel G. Anderson,et al.  Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. , 2008, Cell host & microbe.

[51]  H. Yee,et al.  Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chicken. , 2008, International journal for parasitology.

[52]  Xinxia Peng,et al.  A combined transcriptome and proteome survey of malaria parasite liver stages , 2008, Proceedings of the National Academy of Sciences.

[53]  Nicholas J White,et al.  Vivax malaria: neglected and not benign. , 2007, The American journal of tropical medicine and hygiene.

[54]  S. Kappe,et al.  L-FABP is a critical host factor for successful malaria liver stage development. , 2007, International journal for parasitology.

[55]  Ana Rodriguez,et al.  The silent path to thousands of merozoites: the Plasmodium liver stage , 2006, Nature Reviews Microbiology.

[56]  C. Libert,et al.  The liver stage of Plasmodium berghei inhibits host cell apoptosis , 2005, Molecular microbiology.

[57]  Darcy L. Medica,et al.  Quantitative Dynamics of Plasmodium yoelii Sporozoite Transmission by Infected Anopheline Mosquitoes , 2005, Infection and Immunity.

[58]  Ana Rodriguez,et al.  HGF/MET signalling protects Plasmodium‐infected host cells from apoptosis , 2005, Cellular microbiology.

[59]  M. Mota,et al.  Malaria Vaccines: Back to the Future? , 2005, Science.

[60]  M. Mota,et al.  Migration of Plasmodium sporozoites through cells before infection. , 2001, Science.

[61]  V. Nussenzweig,et al.  Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes , 1993, The Journal of experimental medicine.

[62]  P. Garnham,et al.  Pre-erythrocytic Stage in Mammalian Malaria Parasites , 1948, Nature.

[63]  M. Mota,et al.  Infection by Plasmodium changes shape and stiffness of hepatic cells. , 2012, Nanomedicine : nanotechnology, biology, and medicine.