Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn's disease--final report.

BACKGROUND Wireless capsule endoscopy is a superior diagnostic tool to barium small bowel follow-through and enteroscopy in diagnosing patients with occult blood loss. AIM To compare capsule endoscopy with barium follow-through and entero-computerised tomography in patients with suspected Crohn's disease. SUBJECTS AND METHODS Thirty-five patients with suspected Crohn's disease underwent the three examinations. The radiologist and gastroenterologist were blinded to each other's results. In cases of discrepancy, colonoscopy and ileoscopy were performed. RESULTS Thirty-five patients (22 males), mean age 28.4 years, were included. Eighty-eight percent had abdominal pain, 83% had diarrhoea and 69% had weight loss. The diagnostic yield of capsule endoscopy was 77% versus 23% and 20% of barium and computerised tomography examinations, respectively (P < 0.05). The capsule detected all of the lesions diagnosed by barium follow-through and entero-computerised tomography. CONCLUSIONS Capsule endoscopy is a superior and more sensitive diagnostic tool than barium follow-through and entero-computerised tomography in patients with suspected Crohn's disease.

[1]  Zvi Fireman,et al.  Initial experience of wireless-capsule endoscopy for evaluating occult gastrointestinal bleeding and suspected small bowel pathology. , 2002 .

[2]  G. Ginsberg,et al.  Radiologic and endoscopic diagnosis of Crohn's disease. , 2001, The Surgical clinics of North America.

[3]  J. Herrerias,et al.  Capsule Endoscopy in Patients with Suspected Crohn’s Disease and Negative Endoscopy , 2003, Endoscopy.

[4]  D. Fischer,et al.  Wireless capsule video endoscopy is a superior diagnostic tool in comparison to barium follow-through and computerized tomography in patients with suspected Crohn's disease , 2003, European journal of gastroenterology & hepatology.

[5]  D. Nolan.  The True Yield of the Small-Intestinal Barium Study , 1997, Endoscopy.

[6]  H. Goldberg,et al.  Radiographic findings of the National Cooperative Crohn's Disease Study. , 1979, Gastroenterology.

[7]  H. Carlson.  Perspective: the small bowel examination in the diagnosis of Crohn's disease. , 1986, AJR. American journal of roentgenology.

[8]  D. Sartoris,et al.  Intraosseous and intradiscal gas in association with spinal infection: report of three cases. , 1986, AJR. American journal of roentgenology.

[9]  Paul Swain,et al.  Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: Results of a pilot study. , 2002, Gastrointestinal endoscopy.

[10]  S. Meyers,et al.  The clinical course of regional ileitis , 1959, The American Journal of Digestive Diseases.

[11]  C. Bartram,et al.  Barium studies and ileoscopy compared in children with suspected Crohn's disease. , 1990, Clinical radiology.

[12]  Y Kopelman,et al.  Diagnosing small bowel Crohn’s disease with wireless capsule endoscopy , 2003, Gut.

[13]  Message from the President of the Endoscopy Section of the Hellenic Society of Gastroenterology , 2003 .

[14]  G. Iddan,et al.  Wireless capsule endoscopy , 2000, Nature.