Image-guidance for stereotactic body radiation therapy.

The term stereotactic body radiation therapy (SBRT) describes a recently introduced external beam radiation paradigm by which small lesions outside the brain are treated under stereotactic conditions, in a single or few fractions of high-dose radiation delivery. Similar to the treatment planning and delivery process for cranial radiosurgery, the emphasis is on sparing of adjacent normal tissues through the creation of steep dose gradients. Thus, advanced methods for assuring an accurate relationship between the target volume position and radiation beam geometry, immediately prior to radiation delivery, must be implemented. Such methods can employ imaging techniques such as planar (e.g., x-ray) or volumetric (e.g., computed tomography [CT]) approaches and are commonly summarized under the general term image-guided radiation therapy (IGRT). This review summarizes clinical experience with volumetric and ultrasound based image-guidance for SBRT. Additionally, challenges and potential limitations of pre-treatment image-guidance are presented and discussed.

[1]  F. Lohr,et al.  Noninvasive patient fixation for extracranial stereotactic radiotherapy. , 1999, International journal of radiation oncology, biology, physics.

[2]  V. Khoo,et al.  X-ray volumetric imaging in image-guided radiotherapy: the new standard in on-treatment imaging. , 2006, International journal of radiation oncology, biology, physics.

[3]  Clifton D Fuller,et al.  Daily ultrasound-based image-guided targeting for radiotherapy of upper abdominal malignancies. , 2004, International journal of radiation oncology, biology, physics.

[4]  D A Jaffray,et al.  A radiographic and tomographic imaging system integrated into a medical linear accelerator for localization of bone and soft-tissue targets. , 1999, International journal of radiation oncology, biology, physics.

[5]  F. Lohr,et al.  Stereotactic single-dose radiation therapy of liver tumors: results of a phase I/II trial. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[6]  I. Lax,et al.  Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator. Clinical experience of the first thirty-one patients. , 1995, Acta oncologica.

[7]  M. V. van Herk,et al.  Respiratory correlated cone beam CT. , 2005, Medical physics.

[8]  Lech Papiez,et al.  Extracranial Stereotactic Radiation Delivery: Expansion of Technology Beyond the Brain , 2003, Technology in cancer research & treatment.

[9]  Jingeng Zhu,et al.  Image‐guided and intensity‐modulated radiosurgery for patients with spinal metastasis , 2003, Cancer.

[10]  Bill J Salter,et al.  Repositioning Accuracy of a Commercially Available Double-vacuum Whole Body Immobilization System for Stereotactic Body Radiation Therapy , 2004, Technology in cancer research & treatment.

[11]  M. Oldham,et al.  Cone-beam-CT guided radiation therapy: technical implementation. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[12]  I. Lax,et al.  Stereotactic radiotherapy of malignancies in the abdomen. Methodological aspects. , 1994, Acta oncologica.

[13]  Ping Xia,et al.  Low-dose megavoltage cone-beam CT for radiation therapy. , 2005, International journal of radiation oncology, biology, physics.

[14]  Charles R. Thomas,et al.  External beam radiation therapy for hepatocellular carcinoma: potential of intensity-modulated and image-guided radiation therapy. , 2004, Gastroenterology.

[15]  Michael Flentje,et al.  Stereotactic Radiotherapy of Targets in the Lung and Liver , 2001, Strahlentherapie und Onkologie.

[16]  Icru Prescribing, recording, and reporting photon beam therapy , 1993 .

[17]  F Lohr,et al.  Extracranial stereotactic radiation therapy: set-up accuracy of patients treated for liver metastases. , 2000, International journal of radiation oncology, biology, physics.

[18]  M Kono,et al.  Intrafractional tumor position stability during computed tomography (CT)-guided frameless stereotactic radiation therapy for lung or liver cancers with a fusion of CT and linear accelerator (FOCAL) unit. , 2000, International journal of radiation oncology, biology, physics.

[19]  Angelika Hoess,et al.  Stereotactic single-dose radiotherapy of stage I non-small-cell lung cancer (NSCLC). , 2003, International journal of radiation oncology, biology, physics.

[20]  Radhe Mohan,et al.  Near simultaneous computed tomography image-guided stereotactic spinal radiotherapy: an emerging paradigm for achieving true stereotaxy. , 2003, International journal of radiation oncology, biology, physics.

[21]  Branislav Jeremic,et al.  Stereotactic hypofractionated radiation therapy for stage I non-small cell lung cancer. , 2005, Lung cancer.

[22]  L Xing,et al.  Motion correction for improved target localization with on-board cone-beam computed tomography , 2006, Physics in medicine and biology.