Electronic health records in a Blockchain: A systematic review

Blockchain could reinvent the way patient’s electronic health records are shared and stored by providing safer mechanisms for health information exchange of medical data in the healthcare industry, by securing it over a decentralized peer-to-peer network. Intending to support and ease the understanding of this distributed ledger technology, a solid Systematic Literature Review was conducted, aiming to explore the recent literature on Blockchain and healthcare domain and identify existing challenges and open questions, guided by the raise of research questions regarding EHR in a Blockchain. More than 300 scientific studies published in the last ten years were surveyed, resulting in an up-to-date taxonomy creation, challenges and open questions identified, and the most significant approaches, data types, standards and architectures regarding the use of Blockchain for EHR were assessed and discussed.

[1]  Hyeon-Eui Kim,et al.  Blockchain distributed ledger technologies for biomedical and health care applications , 2017, J. Am. Medical Informatics Assoc..

[2]  Mohsen Guizani,et al.  MeDShare: Trust-Less Medical Data Sharing Among Cloud Service Providers via Blockchain , 2017, IEEE Access.

[3]  Rui Guo,et al.  Secure Attribute-Based Signature Scheme With Multiple Authorities for Blockchain in Electronic Health Records Systems , 2018, IEEE Access.

[4]  K. Rabah.  Challenges & Opportunities for Blockchain Powered Healthcare Systems: A Review , 2017 .

[5]  Vishal Patel,et al.  A framework for secure and decentralized sharing of medical imaging data via blockchain consensus , 2019, Health Informatics J..

[6]  Jaan Priisalu,et al.  Personal control of privacy and data: Estonian experience , 2017, Health and technology.

[7]  U. Krieger,et al.  Advanced block-chain architecture for e-health systems , 2017, 2017 IEEE 19th International Conference on e-Health Networking, Applications and Services (Healthcom).

[8]  K. Clauson,et al.  Pragmatic, Interdisciplinary Perspectives on Blockchain and Distributed Ledger Technology: Paving the Future for Healthcare , 2018 .

[9]  Yue Wang,et al.  Blockchain-based efficient privacy preserving and data sharing scheme of content-centric network in 5G , 2017, IET Commun..

[10]  Wei Jiang,et al.  Healthcare Data Gateways: Found Healthcare Intelligence on Blockchain with Novel Privacy Risk Control , 2016, Journal of Medical Systems.

[11]  Douglas C. Schmidt,et al.  FHIRChain: Applying Blockchain to Securely and Scalably Share Clinical Data , 2018, Computational and structural biotechnology journal.

[12]  Yury Yanovich,et al.  Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare , 2015, Oncotarget.

[13]  Yang Lu,et al.  Healthcare services across China – on implementing an extensible universally unique patient identifier system , 2018 .

[14]  Pearl Brereton,et al.  Performing systematic literature reviews in software engineering , 2006, ICSE.

[15]  S. Nakamoto,et al.  Bitcoin: A Peer-to-Peer Electronic Cash System , 2008 .

[16]  M. Petticrew,et al.  Systematic Reviews in the Social Sciences: A Practical Guide , 2005 .

[17]  Syrene A. Miller,et al.  Evidence-based decision making in action: Part 1--Finding the best clinical evidence. , 2002, The journal of contemporary dental practice.

[18]  Cristiano André da Costa,et al.  OmniPHR: A distributed architecture model to integrate personal health records , 2017, J. Biomed. Informatics.

[19]  Marek A Cyran,et al.  Blockchain as a Foundation for Sharing Healthcare Data , 2018 .

[20]  Pavlos S. Efraimidis,et al.  A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval , 2018, Computational and structural biotechnology journal.

[21]  Andrea Pinna,et al.  A Blockchain Approach Applied to a Teledermatology Platform in the Sardinian Region (Italy) , 2018, Inf..

[22]  S. Jagannatha,et al.  Analysis of Blockchain technology: pros, cons and SWOT , 2018, Cluster Computing.

[23]  Praneeth Babu Marella,et al.  Ancile: Privacy-Preserving Framework for Access Control and Interoperability of Electronic Health Records Using Blockchain Technology , 2018 .

[24]  Fusheng Wang,et al.  Secure and Trustable Electronic Medical Records Sharing using Blockchain , 2017, AMIA.

[25]  Roy H. Campbell,et al.  World of Empowered IoT Users , 2016, 2016 IEEE First International Conference on Internet-of-Things Design and Implementation (IoTDI).

[26]  E. Rodríguez‐Merchán,et al.  How blockchain technology can change medicine , 2018, Postgraduate medicine.

[27]  J. Thomason.  Blockchain: an accelerator for women and children’s health? , 2017 .

[28]  Anastas Mishev,et al.  Blockchain solutions for big data challenges: A literature review , 2017, IEEE EUROCON 2017 -17th International Conference on Smart Technologies.

[29]  Kane Smith,et al.  Blockchain for Digital Crime Prevention: The Case of Health Informatics , 2017, AMCIS.

[30]  Victoria L. Lemieux,et al.  A typology of blockchain recordkeeping solutions and some reflections on their implications for the future of archival preservation , 2017, 2017 IEEE International Conference on Big Data (Big Data).

[31]  Kun Gao,et al.  Deep data analyzing algorithm based on scale space theory , 2017, Cluster Computing.

[32]  Bian Yang,et al.  A Blockchain-based Approach to the Secure Sharing of Healthcare Data , 2017 .

[33]  Daisuke Ichikawa,et al.  Tamper-Resistant Mobile Health Using Blockchain Technology , 2017, JMIR mHealth and uHealth.

[34]  Christian Catalini,et al.  Blockchain Technology for Healthcare: Facilitating the Transition to Patient-Driven Interoperability , 2018, Computational and structural biotechnology journal.

[35]  Hao Wang,et al.  Secure Cloud-Based EHR System Using Attribute-Based Cryptosystem and Blockchain , 2018, Journal of Medical Systems.

[36]  Arpan Kumar Kar,et al.  "Technology enabled Health" - Insights from twitter analytics with a socio-technical perspective , 2018, Int. J. Inf. Manag..

[37]  N. Kshetri.  Blockchain's roles in strengthening cybersecurity and protecting privacy , 2017 .

[38]  Zonyin Shae,et al.  On the Design of a Blockchain Platform for Clinical Trial and Precision Medicine , 2017, 2017 IEEE 37th International Conference on Distributed Computing Systems (ICDCS).

[39]  M. Petticrew,et al.  Systematic Reviews in the Social Sciences , 2006 .

[40]  Jiannong Cao,et al.  BlocHIE: A BLOCkchain-Based Platform for Healthcare Information Exchange , 2018, 2018 IEEE International Conference on Smart Computing (SMARTCOMP).

[41]  Peter B. Nichol,et al.  Co-Creation of Trust for Healthcare: The Cryptocitizen Framework for Interoperability with Blockchain , 2016 .

[42]  Kim-Kwang Raymond Choo,et al.  A blockchain future for internet of things security: a position paper , 2017, Digit. Commun. Networks.

[43]  Lawrence Bodin,et al.  Evaluating information security investments using the analytic hierarchy process , 2005, CACM.

[44]  Andrew Lippman,et al.  A Case Study for Blockchain in Healthcare : “ MedRec ” prototype for electronic health records and medical research data , 2016 .