Magnetic Nanoparticles for In Vivo Applications: A NumericalModeling Study

In vivo applications of biocompatible magnetic nanoparticles in a carrier liquid controlled by an external magnetic field from outside the body have recently been proposed for specific drug delivery such as in locoregional cancer therapies or the occlusion aneurysms. They can also be used as guided contrast agents in myocardial imaging after myocardial infarction. However, the choice of the optimal clinical setting still remains a challenge for all of the mentioned applications. A numerical heterogeneous multiscale model can be used for an optimal a priori determination of the free parameters and might help to overcome this problem.