Tai chi for health benefits in patients with multiple sclerosis: A systematic review

The aim of this systematic review was to evaluate the existing evidence on the effectiveness and safety of Tai chi, which is critical to provide guidelines for clinicians to improve symptomatic management in patients with multiple sclerosis (MS). After performing electronic and manual searches of many sources, ten relevant peer-reviewed studies that met the inclusion criteria were retrieved. The existing evidence supports the effectiveness of Tai chi on improving quality of life (QOL) and functional balance in MS patients. A small number of these studies also reported the positive effect of Tai chi on flexibility, leg strength, gait, and pain. The effect of Tai chi on fatigue is inconsistent across studies. Although the findings demonstrate beneficial effects on improving outcome measures, especially for functional balance and QOL improvements, a conclusive claim should be made carefully for reasons such as methodological flaws, small sample size, lack of specific-disease instruments, unclear description of Tai chi protocol, unreported safety of Tai chi, and insufficient follow-up as documented by the existing literature. Future research should recruit a larger number of participants and utilize the experimental design with a long-term follow-up to ascertain the benefits of Tai chi for MS patients.

[1]  A. Kossaify,et al.  Appropriate Use Criteria in Echocardiography: An Observational Institutional Study with the Perspective of a Quality Improvement Project , 2016, Clinical Medicine Insights. Cardiology.

[2]  Bin Hu,et al.  Effects of Tai Chi and Multimodal Exercise Training on Movement and Balance Function in Mild to Moderate Idiopathic Parkinson Disease , 2015, American journal of physical medicine & rehabilitation.

[3]  Yingzhi Lu,et al.  Simplified Tai Chi Resistance Training versus Traditional Tai Chi in Slowing Bone Loss in Postmenopausal Women , 2015, Evidence-based complementary and alternative medicine : eCAM.

[4]  P. Davidson,et al.  Effect of Tai Chi Chuan on balance in women with multiple sclerosis. , 2015, Complementary therapies in clinical practice.

[5]  Q. Gao,et al.  A Meta-Analysis on the Efficacy of Tai Chi in Patients with Parkinson's Disease between 2008 and 2014 , 2015, Evidence-based complementary and alternative medicine : eCAM.

[6]  Hirofumi Ochi,et al.  [Cognitive impairment in multiple sclerosis]. , 2014, Brain and nerve = Shinkei kenkyu no shinpo.

[7]  Adedayo A Onitilo,et al.  Is It Time for the Cochrane Collaboration to Reconsider Its Meta-Analysis Methodology? , 2014, Clinical Medicine & Research.

[8]  M. Galea,et al.  Management of Fatigue in Persons with Multiple Sclerosis , 2014, Front. Neurol..

[9]  Philipp M. Keune,et al.  Mindfulness-based interventions in multiple sclerosis: beneficial effects of Tai Chi on balance, coordination, fatigue and depression , 2014, BMC Neurology.

[10]  Chengqi He,et al.  Effects of Tai Chi on balance and fall prevention in Parkinson’s disease: a randomized controlled trial , 2014, Clinical rehabilitation.

[11]  M. Hosseini,et al.  Effect of Tai Chi Chuan on Quality of Life in Women with Multiple Sclerosis , 2013 .

[12]  S. Chung,et al.  Therapeutic Effects of Tai Chi in Patients with Parkinson's Disease , 2013, ISRN neurology.

[13]  S. Chandran,et al.  AUTOLOGOUS MESENCHYMAL STEM CELLS FOR THE TREATMENT OF SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS: AN OPEN–LABEL PHASE 2A PROOF–OF–CONCEPT STUDY , 2013 .

[14]  R. Christopher,et al.  Prevalence of fatigue in patients with multiple sclerosis and its effect on the quality of life , 2013, Journal of neurosciences in rural practice.

[15]  J. Corboy,et al.  The association between multiple sclerosis-related fatigue and balance as a function of central sensory integration. , 2013, Gait & posture.

[16]  Kelong Chen,et al.  Impact of depression, fatigue and disability on quality of life in Chinese patients with multiple sclerosis. , 2013, Stress and health : journal of the International Society for the Investigation of Stress.

[17]  K. Baumstarck,et al.  Measuring the Quality of Life in Patients with Multiple Sclerosis in Clinical Practice: A Necessary Challenge , 2013, Multiple sclerosis international.

[18]  A. Turner,et al.  Reforming respiratory outpatient services: a before-and-after observational study assessing the impact of a quality improvement project applying British Thoracic Society criteria to the discharge of patients to primary care , 2013, Primary care respiratory journal : journal of the General Practice Airways Group.

[19]  Janina M. Burschka,et al.  An exploration of impaired walking dynamics and fatigue in Multiple Sclerosis , 2012, BMC Neurology.

[20]  R. Franklin,et al.  Neuroprotection and repair in multiple sclerosis , 2012, Nature Reviews Neurology.

[21]  M. McHugh Interrater reliability: the kappa statistic , 2012, Biochemia medica.

[22]  Vanisha Parekh Parkinson disease: Tai chi improves balance in Parkinson disease , 2012, Nature Reviews Neurology.

[23]  D. Moher,et al.  The nuts and bolts of PROSPERO: an international prospective register of systematic reviews , 2012, Systematic Reviews.

[24]  M. Koeneman,et al.  Determinants of physical activity and exercise in healthy older adults: A systematic review , 2011, The international journal of behavioral nutrition and physical activity.

[25]  R. Günaydın,et al.  Quality of life in patients with multiple sclerosis: the impact of depression, fatigue, and disability , 2011, International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation.

[26]  M. Bird,et al.  The long-term benefits of a multi-component exercise intervention to balance and mobility in healthy older adults. , 2011, Archives of gerontology and geriatrics.

[27]  Jeffrey A. Cohen,et al.  Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria , 2011, Annals of neurology.

[28]  Chenchen Wang,et al.  Tai Chi Exercise for Patients With Cardiovascular Conditions and Risk Factors: A SYSTEMATIC REVIEW , 2009, Journal of cardiopulmonary rehabilitation and prevention.

[29]  Cecilia Lundholm,et al.  Predicting accidental falls in people with multiple sclerosis — a longitudinal study , 2009, Clinical rehabilitation.

[30]  Gammon M Earhart,et al.  Tai Chi improves balance and mobility in people with Parkinson disease. , 2008, Gait & posture.

[31]  M. Irwin,et al.  Improving sleep quality in older adults with moderate sleep complaints: A randomized controlled trial of Tai Chi Chih. , 2008, Sleep.

[32]  Christoph Handschin,et al.  The role of exercise and PGC1α in inflammation and chronic disease , 2008, Nature.

[33]  E. Ernst,et al.  Tai chi for rheumatoid arthritis: systematic review. , 2007, Rheumatology.

[34]  Roger B. Davis,et al.  The effects of Tai Chi on bone mineral density in postmenopausal women: a systematic review. , 2007, Archives of physical medicine and rehabilitation.

[35]  Chi C Cho,et al.  Risk factors for falling among people aged 45 to 90 years with multiple sclerosis. , 2006, Archives of physical medicine and rehabilitation.

[36]  K. Lee,et al.  [The effect of Tai Chi movement in patients with rheumatoid arthritis]. , 2006, Taehan Kanho Hakhoe chi.

[37]  S. Reingold,et al.  Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria” , 2005, Annals of neurology.

[38]  Julián Benito-León,et al.  Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing , 2005, The Lancet Neurology.

[39]  R. Bakshi,et al.  Predicting quality of life in multiple sclerosis: accounting for physical disability, fatigue, cognition, mood disorder, personality, and behavior change , 2005, Journal of the Neurological Sciences.

[40]  A. Solari Role of health-related quality of life measures in the routine care of people with multiple sclerosis , 2005, Health and quality of life outcomes.

[41]  Elizabeth Eckstrom,et al.  Tai Chi and fall reductions in older adults: a randomized controlled trial. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.

[42]  J. Holmes,et al.  What drives quality of life in multiple sclerosis? , 2004, QJM : monthly journal of the Association of Physicians.

[43]  Arianne P Verhagen,et al.  The efficacy of Tai Chi Chuan in older adults: a systematic review. , 2004, Family practice.

[44]  M. Amato,et al.  Quality of life in multiple sclerosis: the impact of depression, fatigue and disability , 2001, Multiple sclerosis.

[45]  A. Tennant,et al.  Health status and quality of life of people with multiple sclerosis , 2001, Disability and rehabilitation.

[46]  A. Thompson,et al.  Does adding MS-specific items to a generic measure (the SF-36) improve measurement? , 2001, Neurology.

[47]  G. Rosati,et al.  The prevalence of multiple sclerosis in the world: an update , 2001, Neurological Sciences.

[48]  N. Mills,et al.  Mindfulness of movement as a coping strategy in multiple sclerosis. A pilot study. , 2000, General hospital psychiatry.

[49]  R. Niederman,et al.  Improving quality of life for people with chronic conditions: the example of t'ai chi and multiple sclerosis. , 1999, Alternative therapies in health and medicine.

[50]  J. Petajan,et al.  Recommendations for Physical Activity in Patients with Multiple Sclerosis , 1999, Sports medicine.

[51]  H. Vet,et al.  The Delphi list: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus. , 1998, Journal of clinical epidemiology.

[52]  J S Wolinsky,et al.  Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability , 1998, Neurology.

[53]  A. Achiron,et al.  Electrical sensation during Tai-Chi practice as the first manifestation of multiple sclerosis , 1997, Clinical Neurology and Neurosurgery.

[54]  S. Wolf,et al.  Exploring the basis for Tai Chi Chuan as a therapeutic exercise approach. , 1997, Archives of physical medicine and rehabilitation.

[55]  J. Fisk,et al.  The Impact of Fatigue on Patients with Multiple Sclerosis , 1994, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[56]  Jebb G. Remelius,et al.  Enhancing postural stability and adaptability in multiple sclerosis. , 2014, Advances in experimental medicine and biology.

[57]  Ashutosh Kumar Singh,et al.  MENTAL TAI CHI-BASED EXERCISE PROGRAMME VS TAI-CHI FOR INDIAN MULTIPLE SCLEROSIS PATIENTS: A PILOT STUDY , 2014 .

[58]  Khoshraftar Yazdi Nahid,et al.  THE EFFECT OF TAI CHI TRAINING PROGRAMS ON WOMEN'S BALANCE WITH MULTIPLE SCLEROSIS , 2013 .

[59]  David H. Miller,et al.  Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study , 2012, The Lancet Neurology.

[60]  S. Planchon,et al.  Effects of meditation on pain and quality of life in multiple sclerosis and peripheral neuropathy: a pilot study. , 2011, International journal of MS care.

[61]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. , 2010, International journal of surgery.

[62]  Christoph Handschin,et al.  The Role of Exercise and Pgc1alpha in Inflammation and Chronic Disease , 2022 .

[63]  C. Roberts,et al.  Effects of exercise and diet on chronic disease. , 2005, Journal of applied physiology.

[64]  M. Galantino,et al.  The Effects of Tai Chi and Walking on Fatigue and Body Mass Index in Women Living with Breast Cancer: A Pilot Study , 2003 .

[65]  N. Mills,et al.  Does Tai Chi/Qi Gong help patients with Multiple Sclerosis? , 2000 .

[66]  R. Jordan,et al.  Treatments for fatigue in multiple sclerosis: a rapid and systematic review. , 2000, Health technology assessment.

[67]  David C Mohr,et al.  Fatigue and multiple sclerosis: evidence-based management strategies for fatigue in multiple sclerosis , 1998 .

[68]  Jacob Cohen QUANTITATIVE METHODS IN PSYCHOLOGY A Power Primer , 1992 .