Longitudinal bleeding assessment in von Willebrand disease utilizing an interim bleeding score

Assessment of bleeding phenotype is critically important in the diagnosis of von Willebrand disease (VWD). Despite advances in bleeding assessment tools (BATs), standardized tools to evaluate bleeding following diagnosis (interim bleeding) are lacking.

[1]  R. Mustafa,et al.  ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. , 2021, Blood advances.

[2]  P. James,et al.  Significant gynecological bleeding in women with low von Willebrand factor levels. , 2018, Blood advances.

[3]  Kenneth L. Jones,et al.  Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels. , 2017, Blood.

[4]  V. Blanchette,et al.  Generation and optimization of the self‐administered pediatric bleeding questionnaire and its validation as a screening tool for von Willebrand disease , 2017, Pediatric blood & cancer.

[5]  D. Bellissimo,et al.  Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States. , 2016, Blood.

[6]  F. Leebeek,et al.  Bleeding spectrum in children with moderate or severe von Willebrand disease: Relevance of pediatric‐specific bleeding , 2015, American journal of hematology.

[7]  Shamim A. Mollah,et al.  Normal range of bleeding scores for the ISTH‐BAT: adult and pediatric data from the merging project , 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

[8]  P. Mannucci,et al.  The bleeding score predicts clinical outcomes and replacement therapy in adults with von Willebrand disease. , 2014, Blood.

[9]  P. James,et al.  Generation and optimization of the self‐administered bleeding assessment tool and its validation as a screening test for von Willebrand disease , 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

[10]  V. Blanchette,et al.  The genetics of Canadian type 3 von Willebrand disease: further evidence for co‐dominant inheritance of mutant alleles , 2013, Journal of thrombosis and haemostasis : JTH.

[11]  P. James,et al.  The evolution and value of bleeding assessment tools , 2012, Journal of thrombosis and haemostasis : JTH.

[12]  M. Nijziel,et al.  Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease , 2012, Thrombosis and Haemostasis.

[13]  A. Tosetto,et al.  A comparison between two semi‐quantitative bleeding scales for the diagnosis and assessment of bleeding severity in type 1 von Willebrand disease , 2011, Haemophilia : the official journal of the World Federation of Hemophilia.

[14]  B. Coller,et al.  ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders , 2010, Journal of thrombosis and haemostasis : JTH.

[15]  R. Hoffmann,et al.  Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. , 2010, Blood.

[16]  P. James,et al.  The prevalence of symptomatic von Willebrand disease in primary care practice , 2010, Journal of thrombosis and haemostasis : JTH.

[17]  P. Mannucci,et al.  Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor , 2006, Journal of thrombosis and haemostasis : JTH.

[18]  A. Tosetto,et al.  A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1 VWD) , 2006, Journal of thrombosis and haemostasis : JTH.

[19]  A. Tosetto,et al.  The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study , 2005, Journal of thrombosis and haemostasis : JTH.

[20]  P. Mannucci.  How I treat patients with von Willebrand disease. , 2001, Blood.

[21]  F Rodeghiero,et al.  Epidemiological investigation of the prevalence of von Willebrand's disease. , 1987, Blood.

[22]  L. O'Brien,et al.  The mutational spectrum of type 1 von Willebrand disease: Results from a Canadian cohort study. , 2007, Blood.