Transgraph: interactive intensity-based 2D/3D registration of x-ray and CT data

This paper presents work towards a system for intra-operative registration of 3D CT data to 2D X-ray radiographs. The registration procedure involves iterative comparison of Digitally Reconstructed Radiographs (DRRs) with X-ray images acquired during surgery. A new data structure called a Transgraph permits rapid generation of DRRS, and greatly speeds up the registration process. The underlying data structures are described, and the registration algorithm is evaluated for application to an existing image guided radiosurgery system.