Microwave heating by using flat LHM lens

Microwave heating system for hyperthermia by using four flat LHM lenses orthogonally-deployed around the heating region is proposed and simulated. For the process of heating a 6 mm-diameter tumor in homogeneous lossy dielectric medium, our 2-D FDTD simulations indicate that microwave energy can be concentrated tightly inside the tumor. Also the temperature distribution is derived through bio-heat equation (BHE), which has been solved by finite differential approach. Due to the admiring focusing properties of LHM lens, the temperature inside the tumor may rise from 37degC to more than 42.65degC during one hour with average input power density of 1.60 W/cm at 6 GHz, while the temperature of normal tissue keeps well below 42degC as the requirement of hyperthermia.

[1]  Paolo Bernardi,et al.  Specific absorption rate and temperature elevation in a subject exposed in the far-field of radio-frequency sources operating in the 10-900-MHz range , 2003, IEEE Transactions on Biomedical Engineering.

[2]  X.T. Dong,et al.  Perfectly matched layer-absorbing boundary condition for left-handed materials , 2004, IEEE Microwave and Wireless Components Letters.

[3]  T. Cui,et al.  Enhancement of specific absorption rate in lossy dielectric objects using a slab of left-handed material. , 2005, Physical review. E, Statistical, nonlinear, and soft matter physics.

[4]  Margarethus M. Paulides,et al.  A Patch Antenna Design for Application in a Phased-Array Head and Neck Hyperthermia Applicator , 2007, IEEE Transactions on Biomedical Engineering.

[5]  A. Taflove,et al.  Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: fixed-focus and antenna-array sensors , 1998, IEEE Transactions on Biomedical Engineering.

[6]  Edward A. Gelvich,et al.  Contact flexible microstrip applicators (CFMA) in a range from microwaves up to short waves , 2002, IEEE Transactions on Biomedical Engineering.

[7]  Adaptive focusing experiments for minimally invasive monopole phased arrays in hyperthermia treatment of breast cancer , 1994, Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[8]  A. Garetsos,et al.  Development and Laboratory Testing of a Noninvasive Intracranial Focused Hyperthermia System , 2008, IEEE Transactions on Microwave Theory and Techniques.

[9]  A. Grbic,et al.  Overcoming the diffraction limit with a planar left-handed transmission-line lens. , 2004, Physical review letters.

[10]  V. Veselago The Electrodynamics of Substances with Simultaneously Negative Values of ∊ and μ , 1968 .

[11]  Y. Nikawa,et al.  Dielectric loaded lens applicator for microwave hyperthermia , 1990, IEEE International Digest on Microwave Symposium.

[12]  T. Cetas,et al.  Current sheet applicators for clinical microwave hyperthermia , 1993 .

[14]  J. Pendry,et al.  Negative refraction makes a perfect lens , 2000, Physical review letters.

[15]  B.D. Van Veen,et al.  Ultrawide-band microwave space-time beamforming for hyperthermia treatment of breast cancer: a computational feasibility study , 2004, IEEE Transactions on Microwave Theory and Techniques.

[16]  Gang Wang,et al.  Resolution of Near-Field Microwave Target Detection and Imaging by Using Flat LHM Lens , 2007, IEEE Transactions on Antennas and Propagation.

[17]  L. Barratt,et al.  Experimental validation of a combined electromagnetic and thermal FDTD model of a microwave heating process , 1995 .