Neural Network Classifier for Automatic Detection of Invasive Versus Noninvasive Airway Management Technique Based on Respiratory Monitoring Parameters in a Pediatric Anesthesia

Children undergoing general anesthesia require airway monitoring by an anesthesia provider. The airway may be supported with noninvasive devices such as face mask or invasive devices such as a laryngeal mask airway or an endotracheal tube. The physiologic data stored provides an opportunity to apply machine learning algorithms distinguish between these modes based on pattern recognition. We retrieved three data sets from patients receiving general anesthesia in 2015 with either mask, laryngeal mask airway or endotracheal tube. Patients underwent myringotomy, tonsillectomy, adenoidectomy or inguinal hernia repair procedures. We retrieved measurements for end-tidal carbon dioxide, tidal volume, and peak inspiratory pressure and calculated statistical features for each data element per patient. We applied machine learning algorithms (decision tree, support vector machine, and neural network) to classify patients into noninvasive or invasive airway device support. We identified 300 patients per group (mask, laryngeal mask airway, and endotracheal tube) for a total of 900 patients. The neural network classifier performed better than the boosted trees and support vector machine classifiers based on the test data sets. The sensitivity, specificity, and accuracy for neural network classification are 97.5%, 96.3%, and 95.8%. In contrast, the sensitivity, specificity, and accuracy of support vector machine are 89.1%, 92.3%, and 88.3% and with the boosted tree classifier they are 93.8%, 92.1%, and 91.4%. We describe a method to automatically distinguish between noninvasive and invasive airway device support in a pediatric surgical setting based on respiratory monitoring parameters. The results show that the neural network classifier algorithm can accurately classify noninvasive and invasive airway device support.

[1]  Ali Jalali,et al.  Prediction of Periventricular Leukomalacia Occurrence in Neonates After Heart Surgery , 2014, IEEE Journal of Biomedical and Health Informatics.

[2]  A F Marquand,et al.  Predicting long-term outcome of Internet-delivered cognitive behavior therapy for social anxiety disorder using fMRI and support vector machine learning , 2015, Translational Psychiatry.

[3]  Does manual anaesthetic record capture remove clinically important data? , 2011, British journal of anaesthesia.

[4]  Eva K. Lee,et al.  Medical Alert Management: A Real-Time Adaptive Decision Support Tool to Reduce Alert Fatigue , 2014, AMIA.

[5]  R. Morris,et al.  Anaesthesia and Fatigue: An Analysis of the First 10 Years of the Australian Incident Monitoring Study 1987–1997 , 2000, Anaesthesia and intensive care.

[6]  C A Bodian,et al.  Arterial Blood Pressure and Heart Rate Discrepancies Between Handwritten and Computerized Anesthesia Records , 2000, Anesthesia and analgesia.

[7]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[8]  Ali Jalali,et al.  Application of decision tree in the prediction of periventricular leukomalacia (PVL) occurrence in neonates after heart surgery , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  Jorge A. Gálvez,et al.  A Narrative Review of Meaningful Use and Anesthesia Information Management Systems , 2015, Anesthesia and analgesia.

[10]  Nitish Srivastava,et al.  Dropout: a simple way to prevent neural networks from overfitting , 2014, J. Mach. Learn. Res..

[11]  Shamim Nemati,et al.  Bayesian nonparametric learning of switching dynamics in cohort physiological time series: application in critical care patient monitoring , 2015 .

[12]  Ming-Chui Dong,et al.  Hierarchical Probabilistic Support Vector Machine for Detecting Cardiovascular Diseases , 2014 .

[13]  Insup Lee,et al.  Prediction of Critical Pulmonary Shunts in Infants , 2016, IEEE Transactions on Control Systems Technology.

[14]  Peter J. Embi,et al.  Evaluating alert fatigue over time to EHR-based clinical trial alerts: findings from a randomized controlled study , 2012, J. Am. Medical Informatics Assoc..

[15]  Allan F. Simpao,et al.  The reliability of manual reporting of clinical events in an anesthesia information management system (AIMS) , 2012, Journal of Clinical Monitoring and Computing.

[16]  Simon Haykin,et al.  Neural Networks: A Comprehensive Foundation , 1998 .

[17]  A. Atiya,et al.  Learning with Kernels: Support Vector Machines, Regularization, Optimization, and Beyond , 2005, IEEE Transactions on Neural Networks.

[18]  R. Dutton Quality improvement and patient safety organizations in anesthesiology. , 2015, AMA journal of ethics.

[19]  T. Short,et al.  Drug error in anaesthetic practice: a review of 896 reports from the Australian Incident Monitoring Study database , 2005, Anaesthesia.

[20]  J. Adriani Anesthesia for Infants and Children , 1964, The American journal of nursing.

[21]  K. Catchpole,et al.  Safety in anaesthesia: a study of 12 606 reported incidents from the UK National Reporting and Learning System , 2008, Anaesthesia.

[22]  Shamim Nemati,et al.  Semisupervised ECG Ventricular Beat Classification With Novelty Detection Based on Switching Kalman Filters , 2015, IEEE Transactions on Biomedical Engineering.

[23]  Jonas S. Almeida,et al.  Machine learning to predict extubation outcome in premature infants , 2013, The 2013 International Joint Conference on Neural Networks (IJCNN).

[24]  R. Dutton,et al.  Making a difference: the Anesthesia Quality Institute. , 2015, Anesthesia and analgesia.

[25]  M Benson,et al.  Comparison of manual and automated documentation of adverse events with an Anesthesia Information Management System (AIMS). , 2000, Studies in health technology and informatics.

[26]  K. Borgwardt,et al.  Machine Learning in Medicine , 2015, Mach. Learn. under Resour. Constraints Vol. 3.

[27]  Ming Yang,et al.  Comparison of machine learning methods for stationary wavelet entropy-based multiple sclerosis detection: decision tree, k-nearest neighbors, and support vector machine , 2016, Simul..

[28]  A. Jalali,et al.  Automatic Detection of Endotracheal Intubation During the Anesthesia Procedure. , 2016, Journal of dynamic systems, measurement, and control.

[29]  Bernhard Schölkopf,et al.  New Support Vector Algorithms , 2000, Neural Computation.

[30]  Geoffrey E. Hinton,et al.  Deep Learning , 2015, Nature.