The cluster glycoside effect.

[1]  F. Santoyo-González,et al.  1,3-dipolar cycloadditions as a tool for the preparation of multivalent structures. , 2000, Organic letters.

[2]  E. W. Meijer,et al.  About Dendrimers: Structure, Physical Properties, and Applications. , 1999, Chemical reviews.

[3]  Dudley H. Williams,et al.  The cost of conformational order: entropy changes in molecular associations , 1992 .

[4]  C. Mandenius,et al.  A Carbohydrate Biosensor Surface for the Detection of Uropathogenic Bacteria , 1994, Bio/Technology.

[5]  D. Myszka,et al.  Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors. , 1997, Current opinion in biotechnology.

[6]  P. Privalov,et al.  Problems and prospects in microcalorimetry of biological macromolecules. , 2000, Methods in enzymology.

[7]  C. Kirmaier,et al.  Studies on selectin-carbohydrate interactions. , 1995, Advances in experimental medicine and biology.

[8]  Christopher L. Brown,et al.  Synthesis of Glycodendrimers by Modification of Poly(propylene imine) Dendrimers , 1997 .

[9]  T. Lindhorst,et al.  Glucose‐Based AB2‐Building Blocks for the Construction of Branched Glycopeptidomimetics , 2000 .

[10]  Mary C. Chervenak,et al.  A Direct Measure of the Contribution of Solvent Reorganization to the Enthalpy of Binding , 1994 .

[11]  J. M. Benito,et al.  Synthesis and comparative lectin-binding affinity of mannosyl-coated β-cyclodextrin-dendrimer constructs , 2000 .

[12]  Y. Aoyama,et al.  Solution-to-Surface Molecular-Delivery System Using a Macrocyclic Sugar Cluster. Sugar-Directed Adsorption of Guests in Water on Polar Solid Surfaces , 1997 .

[13]  Christopher L. Brown,et al.  A CONVERGENT SYNTHESIS OF A CARBOHYDRATE-CONTAINING DENDRIMER , 1997 .

[14]  J. F. Stoddart,et al.  Synthesis and biological evaluation of α-D-mannopyranoside-containing dendrimers , 1998 .

[15]  A. Otter,et al.  Thermodynamic and Conformational Implications of Glycosidic Rotamers Preorganized for Binding , 1998 .

[16]  R. Roy,et al.  Synthesis of Per-Glycosylated β-Cyclodextrins Having Enhanced Lectin Binding Affinity , 1999 .

[17]  R. Roy,et al.  Synthesis of N,N'-bis(acrylamido)acetic acid-based T-antigen glycodendrimers and their mouse monoclonal IgG antibody binding properties. , 2001, Journal of the American Chemical Society.

[18]  L. Kiessling,et al.  A General Synthetic Route to Defined, Biologically Active Multivalent Arrays , 1999 .

[19]  R. Roy,et al.  PRACTICAL SYNTHESIS OF STARBURST PAMAM ALPHA -THIOSIALODENDRIMERS FOR PROBING MULTIVALENT CARBOHYDRATE-LECTIN BINDING PROPERTIES , 1998 .

[20]  W. Jencks,et al.  Entropic contributions to rate accelerations in enzymic and intramolecular reactions and the chelate effect. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[21]  G. Ercolani.  Comment on "Using a Convenient, Quantitative Model for Torsional Entropy To Establish Qualitative Trends for Molecular Processes That Restrict Conformational Freedom" , 1999, The Journal of organic chemistry.

[22]  R. Roy,et al.  Synthesis of antigenic copolymers of N-acetylneuraminic acid binding to wheat germ agglutinin and antibodies. , 1988, Carbohydrate research.

[23]  S. Nishimura,et al.  A Highly Practical Synthesis of Cyclodextrin-Based Glycoclusters Having Enhanced Affinity with Lectins , 2000 .

[24]  L. Bhattacharyya,et al.  Interactions of concanavalin A with asparagine-linked glycopeptides. Structure/activity relationships of the binding and precipitation of oligomannose and bisected hybrid-type glycopeptides with concanavalin A. , 1989, European journal of biochemistry.

[25]  L. Kiessling,et al.  Scope of Multivalent Ligand Function: Lactose-Bearing Neoglycopolymers By Ring-Opening Metathesis Polymerization , 1999 .

[26]  M. I. Khan,et al.  Interactions of concanavalin A with asparagine-linked glycopeptides: formation of homogeneous cross-linked lattices in mixed precipitation systems. , 1988, Biochemistry.

[27]  R. Roy,et al.  Syntheses and some applications of chemically defined multivalent glycoconjugates. , 1996, Current opinion in structural biology.

[28]  M. Okada,et al.  Globular Carbohydrate Macromolecule “Sugar Balls” IV. Synthesis of Dendritic Nanocapsules with Molecular Recognition Sites on Periphery , 1999 .

[29]  Kazukiyo Kobayashi,et al.  Rigid Helical Poly(glycosyl phenyl isocyanide)s: Synthesis, Conformational Analysis, and Recognition by Lectins , 1999 .

[30]  R. Kramer,et al.  Spanning binding sites on allosteric proteins with polymer-linked ligand dimers , 1998, Nature.

[31]  T. Lowary,et al.  Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries , 1998 .

[32]  G. Whitesides,et al.  Nonstatistical binding of a protein to clustered carbohydrates. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[33]  D. Mirejovsky,et al.  HEAT CAPACITIES OF SOLUTION FOR ALCOHOLS IN POLAR SOLVENTS AND THE NEW VIEW OF HYDROPHOBIC EFFECTS , 1983 .

[34]  K. Matsuoka,et al.  Introduction of monosaccharides having functional groups onto a carbosilane dendrimer: a broadly applicable one-pot reaction in liquid ammonia involving Birch reduction and subsequent SN2 reaction. , 2000, Carbohydrate research.

[35]  W. DeGrado,et al.  Hydrophobic core malleability of a de novo designed three-helix bundle protein. , 2001, Journal of molecular biology.

[36]  S. Akimoto,et al.  Synthesis of artificial glycoconjugate polymers starting from enzymatically synthesized oligosaccharides and their interactions with lectins. , 1998, Journal of biochemistry.

[37]  A. Velázquez‐Campoy,et al.  Isothermal titration calorimetry , 1990 .

[38]  J. Gardiner.  The therapeutic potential of synthetic multivalent carbohydrates. , 1998, Expert opinion on investigational drugs.

[39]  L. Kiessling,et al.  Neoglycopolymers produced by aqueous ring-opening metathesis polymerization: Decreasing saccharide density increases activity , 1997 .

[40]  Milos V. Novotny,et al.  Increased protein backbone conformational entropy upon hydrophobic ligand binding , 1999, Nature Structural Biology.

[41]  R. Roy,et al.  Chemical Modification of Chitosan. 3. Hyperbranched Chitosan−Sialic Acid Dendrimer Hybrid with Tetraethylene Glycol Spacer , 2000 .

[42]  C. Ceccarini,et al.  Concanavalin A interactions with asparagine-linked glycopeptides. Bivalency of high mannose and bisected hybrid type glycopeptides. , 1987, The Journal of biological chemistry.

[43]  Tomoya Kinumi,et al.  Affinity of a vancomycin polymer with bacterial surface models , 2001 .

[44]  P. Andrews,et al.  Functional group contributions to drug-receptor interactions. , 1984, Journal of medicinal chemistry.

[45]  K. Drickamer.  Multiplicity of lectin-carbohydrate interactions , 1995, Nature Structural Biology.

[46]  S. Gellman,et al.  12-Helix Formation in Aqueous Solution with Short β-Peptides Containing Pyrrolidine-Based Residues , 2000 .

[47]  R. Roy,et al.  Chemical Modification of Chitosan. 10.1 Synthesis of Dendronized Chitosan−Sialic Acid Hybrid Using Convergent Grafting of Preassembled Dendrons Built on Gallic Acid and Tri(ethylene glycol) Backbone , 2001 .

[48]  E. Toone,et al.  SPATIAL ORGANIZATION VERSUS TOTAL SURFACE AREA AS A PREDICTOR OF PROTEIN HYDROPHOBICITY. THE HYDROPHOBICITY OF THE CONCANAVALIN A BINDING SITE , 1995 .

[49]  H. Caro,et al.  Cyclodextrin-Scaffolded Glycoclusters , 1998 .

[50]  L. Kiessling,et al.  Strength in numbers: non-natural polyvalent carbohydrate derivatives. , 1996, Chemistry & biology.

[51]  S. Gellman,et al.  Solution Conformations of Helix-Forming β-Amino Acid Homooligomers , 2000 .

[52]  R. Roy,et al.  Effect of shape, size, and valency of multivalent mannosides on their binding properties to phytohemagglutinins , 1998, Glycoconjugate Journal.

[53]  A. Mildvan,et al.  15N NMR relaxation studies of free and inhibitor-bound 4-oxalocrotonate tautomerase: backbone dynamics and entropy changes of an enzyme upon inhibitor binding. , 1996, Biochemistry.

[54]  Luke S. S. Guo,et al.  Sialyl Lewis x Liposomes as a Multivalent Ligand and Inhibitor of E-Selectin Mediated Cellular Adhesion , 1996 .

[55]  T. Koyama,et al.  An alternative route for the construction of carbosilane dendrimers uniformly functionalized with lactose or sialyllactose moieties , 2001 .

[56]  R J Read,et al.  Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3. , 1998, Biochemistry.

[57]  E. Toone,et al.  On the Meaning of Affinity:  Cluster Glycoside Effects and Concanavalin A , 1999 .

[58]  R. Roy,et al.  Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen , 2001 .

[59]  George M. Whitesides,et al.  Using a Convenient, Quantitative Model for Torsional Entropy To Establish Qualitative Trends for Molecular Processes That Restrict Conformational Freedom , 1998 .

[60]  Chi‐Huey Wong,et al.  A Lysoganglioside/Poly-L-glutamic Acid Conjugate as a Picomolar Inhibitor of Influenza Hemagglutinin. , 1998, Angewandte Chemie.

[61]  W. DeGrado,et al.  The twists and turns of beta-peptides. , 1999, The journal of peptide research : official journal of the American Peptide Society.

[62]  T. Lindhorst,et al.  Synthesis of octopus glycosides: core molecules for the construction of glycoclusters and carbohydrate-centered dendrimers , 1998 .

[63]  R. Roy,et al.  Macromolecular recognition: effect of multivalency in the inhibition of binding of yeast mannan to concanavalin A and pea lectins by mannosylated dendrimers. , 1996, Bioorganic & medicinal chemistry.

[64]  S. Ley,et al.  Assembly of dendritic glycoclusters from monomeric mannose building blocks , 1998 .

[65]  J. F. Stoddart,et al.  Synthesis of Carbohydrate-Containing Dendrimers. 5. Preparation of Dendrimers Using Unprotected Carbohydrates , 1997 .

[66]  R. Roy,et al.  Chemoenzymatic synthesis and lectin binding properties of dendritic N-acetyllactosamine. , 1997, Bioconjugate chemistry.

[67]  R. Roy,et al.  Highly Convergent Synthesis of Dendrimerized Chitosan−Sialic Acid Hybrid1 , 2001 .

[68]  M. Ballauff.  Structure of Dendrimers in Dilute Solution , 2001 .

[69]  N. Bovin,et al.  Synthetic polymeric sialoside inhibitors of influenza virus receptor‐binding activity , 1990, FEBS letters.

[70]  D G Myszka,et al.  Advances in surface plasmon resonance biosensor analysis. , 2000, Current opinion in biotechnology.

[71]  X. Gong,et al.  A family of concanavalin A-binding peptides from a hexapeptide epitope library. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[72]  Christopher M. Summa,et al.  De novo design and structural characterization of proteins and metalloproteins. , 1999, Annual review of biochemistry.

[73]  I. Goldstein,et al.  Enzyme-linked lectin assay (ELLA). II. Detection of carbohydrate groups on the surface of unfixed cells. , 1984, Experimental cell research.

[74]  B. Ernst,et al.  Synthesis and characterization of polyaspartic acid-carbohydrate conjugates: Multivalent sialyl lewis , 1997 .

[75]  Thisbe K Lindhorst,et al.  Inhibition of the type 1 fimbriae-mediated adhesion of Escherichia coli to erythrocytes by multiantennary α-mannosyl clusters: The effect of multivalency , 1998, Glycoconjugate Journal.

[76]  L. Bhattacharyya,et al.  Formation of homogeneous carbohydrate-lectin cross-linked precipitates from mixtures of D-galactose/N-acetyl-D-galactosamine-specific lectins and multiantennary galactosyl carbohydrates. , 1992, European journal of biochemistry.

[77]  R. Roy,et al.  Multivalent neoglycoconjugates: solid-phase synthesis of N-linked α-sialodendrimers , 1997 .

[78]  K. Aoshima,et al.  Utilization of dendritic framework as a multivalent ligand: a functionalized gadolinium(III) carrier with glycoside cluster periphery , 2000 .

[79]  E. Toone,et al.  A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A , 2000 .

[80]  David D. Manning,et al.  Neoglycopolymer inhibitors of the selectins , 1997 .

[81]  B. Sigurskjold,et al.  Exact analysis of competition ligand binding by displacement isothermal titration calorimetry. , 2000, Analytical biochemistry.

[82]  K. Matsuoka,et al.  SYNTHETIC ASSEMBLY OF TRISACCHARIDE MOIETIES OF GLOBOTRIAOSYL CERAMIDE USING CARBOSILANE DENDRIMERS AS CORES. A NEW TYPE OF FUNCTIONAL GLYCO-MATERIAL , 1999 .

[83]  M. Ge,et al.  Polyvalent binding to carbohydrates immobilized on an insoluble resin. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[84]  A. Imberty,et al.  Synthesis and Conformational Analysis of a Conformationally Constrained Trisaccharide, and Complexation Properties with Concanavalin A , 1999 .

[85]  D. Fushman,et al.  Backbone dynamics of ribonuclease T1 and its complex with 2′GMP studied by two-dimensional heteronuclear NMR spectroscopy , 1994, Journal of biomolecular NMR.

[86]  J. F. Stoddart,et al.  Stable Langmuir and Langmuir-Blodgett films of fullerene-glycodendron conjugates , 1998 .

[87]  Y. Inada,et al.  Biomedical and biotechnological applications of PEG- and PM-modified proteins. , 1995, Trends in biotechnology.

[88]  P G Schultz,et al.  Peptide ligands for a sugar-binding protein isolated from a random peptide library. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[89]  C. Schengrund,et al.  Oligosaccharide-derivatized dendrimers: defined multivalent inhibitors of the adherence of the cholera toxin B subunit and the heat labile enterotoxin of E. coli to GM1 , 2004, Glycoconjugate Journal.

[90]  R. Schnaar,et al.  Substructural specificity and polyvalent carbohydrate recognition by the Entamoeba histolytica and rat hepatic N-acetylgalactosamine/galactose lectins. , 1998, Glycobiology.

[91]  B D Sykes,et al.  Dynamics and thermodynamics of the regulatory domain of human cardiac troponin C in the apo- and calcium-saturated states. , 1998, Biochemistry.

[92]  Ronald W. Barrett,et al.  Peptides Which Bind to E-selectin and Block Neutrophil Adhesion (*) , 1995, The Journal of Biological Chemistry.

[93]  Dustin J Maly,et al.  Probing Low Affinity and Multivalent Interactions with Surface Plasmon Resonance: Ligands for Concanavalin A , 1998 .

[94]  P. Stewart,et al.  Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1. , 1999, Journal of immunology.

[95]  L. Baum,et al.  Apoptosis of T cells mediated by galectin-1 , 1995, Nature.

[96]  T. Toyokuni,et al.  Synthetic carbohydrate vaccines based on tumour-associated antigens , 1996 .

[97]  R. Roy,et al.  Synthesis of New α-Thiosialodendrimers and Their Binding Properties to the Sialic Acid Specific Lectin from Limax flavus , 1997 .

[98]  L. Kay,et al.  Contributions to conformational entropy arising from bond vector fluctuations measured from NMR-derived order parameters: application to protein folding. , 1996, Journal of molecular biology.

[99]  M. Kanai,et al.  Varying the Size of Multivalent Ligands: The Dependence of Concanavalin A Binding on Neoglycopolymer Length , 1997 .

[100]  B. Svensson,et al.  Thermodynamics of inhibitor binding to the catalytic site of glucoamylase from Aspergillus niger determined by displacement titration calorimetry. , 1994, Biochemistry.

[101]  D. Seebach,et al.  The Outstanding Biological Stability of β‐ and γ‐Peptides toward Proteolytic Enzymes: An In Vitro Investigation with Fifteen Peptidases , 2001 .

[102]  R. Roy,et al.  New strategy in glycopolymer synthesis. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl beta-lactoside). , 1992, Bioconjugate chemistry.

[103]  P. Kitov,et al.  The synthesis of 16-mercaptohexadecanyl glycosides for biosensor applications. , 1998, Carbohydrate research.

[104]  Yuan-chuan Lee,et al.  Carbohydrate-Protein Interactions: Basis of Glycobiology , 1995 .

[105]  H. Parrot-Lopez,et al.  Synthesis of Cyclodextrin Derivatives Carrying Bio-Recognisable Saccharide Antennae , 1997 .

[106]  W. Hol,et al.  High-Affinity Pentavalent Ligands of Escherichia coli Heat-Labile Enterotoxin by Modular Structure-Based Design , 2000 .

[107]  Y. Inada,et al.  Chemical modification of proteins with polyethylene glycols , 1995 .

[108]  N. Greenspan,et al.  Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[109]  Chi‐Huey Wong,et al.  Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids , 1998 .

[110]  William A. Goddard,et al.  Starburst Dendrimers: Molecular‐Level Control of Size, Shape, Surface Chemistry, Topology, and Flexibility from Atoms to Macroscopic Matter , 1990 .

[111]  E. Freire,et al.  Thermodynamic mapping of the inhibitor site of the aspartic protease endothiapepsin. , 1995, Journal of molecular biology.

[112]  W. Zhang,et al.  Bacteria targeted by human natural antibodies using alpha-Gal conjugated receptor-specific glycopolymers. , 1999, Bioorganic & medicinal chemistry.

[113]  M. Meldal,et al.  Synthetic methods of glycopeptide assembly, and biological analysis of glycopeptide products. , 1997, Current opinion in chemical biology.

[114]  N. Bovin,et al.  Synthetic polymeric inhibitors of influenza virus receptor-binding activity suppress virus replication. , 1994, Antiviral research.

[115]  Andreas Ide,et al.  Self-Assembled Monolayer of Sugar-Carrying Polymer Chain: Sugar Balls from 2-Methacryloyloxyethyl d-Glucopyranoside† , 1999 .

[116]  L. Bhattacharyya,et al.  Concanavalin A interactions with asparagine-linked glycopeptides. Bivalency of bisected complex type oligosaccharides. , 1987, The Journal of biological chemistry.

[117]  E. Toone,et al.  Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides. , 2000, The Journal of organic chemistry.

[118]  O. Hindsgaul,et al.  Synthesis of Simple Multivalent β-D-GalNAc-(1→4)-β-D-Gal Oligomers as Probes for Investigating the Interactions of P. Aeruginosa Pili with Multivalent Receptors , 1999 .

[119]  T. Lindhorst,et al.  Synthesis of carbohydrate-centered oligosaccharide mimetics equipped with a functionalized tether. , 2000, The Journal of organic chemistry.

[120]  George M. Whitesides,et al.  Using Surface Plasmon Resonance to Study the Binding of Vancomycin and Its Dimer to Self-Assembled Monolayers Presenting d-Ala-d-Ala , 1999 .

[121]  R. Alon,et al.  Inhibition of L-selectin-mediated Leukocyte Rolling by Synthetic Glycoprotein Mimics* , 1999, The Journal of Biological Chemistry.

[122]  L. Kiessling,et al.  Synthetic multivalent ligands in the exploration of cell-surface interactions. , 2000, Current opinion in chemical biology.

[123]  A J Wand,et al.  Insights into the local residual entropy of proteins provided by NMR relaxation , 1996, Protein science : a publication of the Protein Society.

[124]  J. F. Stoddart,et al.  SYNTHESIS OF OLIGOSACCHARIDE DENDRIMERS , 1998 .

[125]  A. Palmer,et al.  Effects of ion binding on the backbone dynamics of calbindin D9k determined by 15N NMR relaxation. , 1993, Biochemistry.

[126]  A. Suzuki,et al.  A streptavidin-based neoglycoprotein carrying more than 140 GT1b oligosaccharides: quantitative estimation of the binding specificity of murine sialoadhesin expressed on CHO cells. , 1998, Journal of biochemistry.

[127]  W. Binder,et al.  Synthesis of a symmetric multivalent molecule containing four carbohydrate substituents , 1995 .

[128]  J. P. Carver,et al.  Oligosaccharides: How can flexible molecules act as signals? , 1993 .

[129]  J. Sacchettini,et al.  Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction. , 2001, Biochemistry.

[130]  Arthur G. Palmer,et al.  NMR order parameters and free energy: an analytical approach and its application to cooperative calcium(2+) binding by calbindin D9k , 1993 .

[131]  D. Russell,et al.  Self-Assembled Carbohydrate Monolayers: Formation and Surface Selective Molecular Recognition , 1998 .

[132]  Basil I. Swanson,et al.  Characterization of Self-Assembled Monolayers for Biosensor Applications , 2000 .

[133]  T. Lindhorst,et al.  Glycocoating of Oligovalent Amines: Synthesis of Thiourea‐Bridged Cluster Glycosides from Glycosyl Isothiocyanates , 1996 .

[134]  J. F. Stoddart,et al.  An efficient synthesis of cyclodextrin-based carbohydrate cluster compounds. , 2000, Organic letters.

[135]  R. Read,et al.  Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands , 2000, Nature.

[136]  L. Kiessling,et al.  Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions. , 2000, Chemistry & biology.

[137]  D. Seebach,et al.  Synthesis and CD Spectra in MeCN, MeOH, and H2O ofγ-Oligopeptides with Hydroxy Groups on the Backbone, Preliminary Communication , 2001 .

[138]  David D. Manning,et al.  Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors , 1997 .

[139]  G. Magnusson,et al.  Analogues of Glycosphingolipids and Glycerolipids Suitable for Conjugation to Gold- and Amino-Functionalised Surfaces , 2000 .

[140]  George R. Newkome,et al.  MICELLES. PART 1. CASCADE MOLECULES: A NEW APPROACH TO MICELLES. A (27)-ARBOROL , 1985 .

[141]  M. Palcic,et al.  Chemoenzymatic synthesis of dendritic sialyl Lewis(x). , 1997, Carbohydrate research.

[142]  S. Saavedra,et al.  Quantitative Studies of Binding between Synthetic Galactosyl Ceramide Analogues and HIV-1 Gp120 at Planar Membrane Surfaces. , 2001, Angewandte Chemie.

[143]  W. Jencks,et al.  On the attribution and additivity of binding energies. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[144]  A. Perelson,et al.  Equilibrium binding of multivalent ligands to cells: effects of cell and receptor density. , 1995, Mathematical biosciences.

[145]  M. I. Khan,et al.  Formation of highly ordered cross-linked lattices between asparagine-linked oligosaccharides and lectins observed by electron microscopy. , 1989, Journal of Biological Chemistry.

[146]  L. Kiessling,et al.  Recognition Specificity of Neoglycopolymers Prepared by Ring-Opening Metathesis Polymerization , 1996 .

[147]  S. Fesik,et al.  Backbone dynamics of the C-terminal domain of Escherichia coli topoisomerase I in the absence and presence of single-stranded DNA. , 1996, Biochemistry.

[148]  A. Doig,et al.  Rotamer strain energy in protein helices - quantification of a major force opposing protein folding. , 2001, Journal of molecular biology.

[149]  R. Wood.  XLII. On a remarkable case of uneven distribution of light in a diffraction grating spectrum , 1902 .

[150]  James R. Dewald,et al.  A New Class of Polymers: Starburst-Dendritic Macromolecules , 1985 .

[151]  M. Hämäläinen,et al.  Identification and optimization of regeneration conditions for affinity-based biosensor assays. A multivariate cocktail approach. , 1999, Analytical chemistry.

[152]  D. Myszka,et al.  Improving biosensor analysis , 1999, Journal of molecular recognition : JMR.

[153]  G. Whitesides,et al.  Polyacrylamides Bearing Pendant α-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus: The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent Interactions , 1996 .

[154]  D. Bray,et al.  Computer-based analysis of the binding steps in protein complex formation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[155]  Timothy M. Miller,et al.  Synthesis of four generations of monodisperse aryl ester dendrimers based on 1,3,5-benzenetricarboxylic acid , 1992 .

[156]  E. Lai,et al.  Surface plasmon resonance-based immunoassays. , 2000, Methods.

[157]  Tomikazu Sasaki,et al.  Iron(II)-Assisted Assembly of Trivalent GalNAc Clusters and Their Interactions with GalNAc-Specific Lectins , 1999 .

[158]  C. Hawker.  3-Dimensional dendritic macromolecules , 1999 .

[159]  M. Stone,et al.  NMR relaxation studies of the role of conformational entropy in protein stability and ligand binding. , 2001, Accounts of chemical research.

[160]  H. Gabius,et al.  Lactose-containing starburst dendrimers: influence of dendrimer generation and binding-site orientation of receptors (plant/animal lectins and immunoglobulins) on binding properties. , 1999, Glycobiology.

[161]  Chi‐Huey Wong,et al.  Design and synthesis of cyclic sialyl Lewis X mimetics: a remarkable enhancement of inhibition by pre-organizing all essential functional groups ☆ , 2000 .

[162]  J. Parquette,et al.  Disaccharide synthesis on a soluble hyperbranched polymer , 1999 .

[163]  George R. Newkome,et al.  Micelles. Part 1. Cascade molecules: a new approach to micelles. A [27]-arborol , 1985 .

[164]  L. Kiessling,et al.  Synergistic Formation of Soluble Lectin Clusters by a Templated Multivalent Saccharide Ligand , 2000 .

[165]  P. Wildt,et al.  Wheat germ agglutinin induces mating reactions in Chlamydomonas eugametos by cross-linking agglutinin-associated glycoproteins in the flagellar membrane , 1989, The Journal of cell biology.

[166]  V. Wittmann,et al.  Combinatorial Solid-Phase Synthesis of Multivalent Cyclic Neoglycopeptides. , 2000, Angewandte Chemie.

[167]  G. Whitesides,et al.  Generation and in Situ Evaluation of Libraries of Poly(acrylic acid) Presenting Sialosides as Side Chains as Polyvalent Inhibitors of Influenza-Mediated Hemagglutination , 1997 .

[168]  S. Gellman,et al.  (R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. , 2000, The Journal of organic chemistry.

[169]  S J Tendler,et al.  Surface plasmon resonance analysis of dynamic biological interactions with biomaterials. , 2000, Biomaterials.

[170]  C. O. Mellet,et al.  Thioureido-β-cyclodextrins as molecular carriers , 1996 .

[171]  R. Patch,et al.  Multivalent Templated Saccharides: Convenient Syntheses of Spacer-Linked 1,1‘-Bis -and 1,1‘,1‘‘-Tris-β-glycosides by the Glycal Epoxide Glycosidation Method , 1997 .

[172]  J. Mitchell,et al.  A direct method for the formation of peptide and carbohydrate dendrimers. , 1999, Bioorganic & medicinal chemistry letters.

[173]  S. Das,et al.  Binding of multivalent carbohydrates to concanavalin A and Dioclea grandiflora lectin. Thermodynamic analysis of the "multivalency effect". , 2000, The Journal of biological chemistry.

[174]  G. Whitesides,et al.  Polyacrylamides bearing pendant .alpha.-sialoside groups strongly inhibit agglutination of erythrocytes by influenza virus , 1991 .

[175]  Z. Zhang,et al.  Low-affinity binding determined by titration calorimetry using a high-affinity coupling ligand: a thermodynamic study of ligand binding to protein tyrosine phosphatase 1B. , 1998, Analytical biochemistry.

[176]  Ralph G. Nuzzo,et al.  ADSORPTION OF BIFUNCTIONAL ORGANIC DISULFIDES ON GOLD SURFACES , 1983 .

[177]  M. Meldal.  Recent developments in glycopeptide and oligosaccharide synthesis , 1994 .

[178]  J. Baker,et al.  Inhibition of viral adhesion and infection by sialic-acid-conjugated dendritic polymers. , 1999, Bioconjugate chemistry.

[179]  S. Ehlers,et al.  Trivalent α-D-mannoside clusters as inhibitors of type-1 fimbriae-mediated adhesion of Escherichia coli: structural variation and biotinylation , 2001 .

[180]  George M Whitesides,et al.  Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors. , 1998, Angewandte Chemie.

[181]  D. Raleigh,et al.  De novo design of helical bundles as models for understanding protein folding and function. , 2000, Accounts of chemical research.