New synthetic routes to thyroid hormone analogs: d6-sobetirome, 3H-sobetirome, and the antagonist NH-3.

[1]  P. Calabresi,et al.  A selective thyroid hormone β receptor agonist enhances human and rodent oligodendrocyte differentiation , 2014, Glia.

[2]  E. Génin,et al.  Induction of the adrenoleukodystrophy-related gene (ABCD2) by thyromimetics , 2009, The Journal of Steroid Biochemistry and Molecular Biology.

[3]  Thomas S. Scanlan,et al.  Sobetirome: a case history of bench-to-clinic drug discovery and development , 2010, Heart Failure Reviews.

[4]  J. McMurray,et al.  Pd-C-induced catalytic transfer hydrogenation with triethylsilane. , 2007, The Journal of organic chemistry.

[5]  J. Baxter,et al.  Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. , 2002, Journal of medicinal chemistry.

[6]  T. Scanlan,et al.  Improved synthesis of the iodine-free thyromimetic GC-1. , 2000, Bioorganic & medicinal chemistry letters.

[7]  G. Cahiez,et al.  Preparation of Highly Functionalized Grignard Reagents by an Iodine-Magnesium Exchange Reaction and its Application in Solid-Phase Synthesis. , 1998, Angewandte Chemie.

[8]  J. Baxter,et al.  A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. , 1998, Chemistry & biology.

[9]  S. Falling,et al.  An efficient and selective method for the preparation of iodophenols , 1990 .

[10]  M. Doyle,et al.  Silane reductions in acidic media. II. Reductions of aryl aldehydes and ketones by trialkylsilanes in trifluoroacetic acid. Selective method for converting the carbonyl group to methylene , 1973 .

[11]  E. Corey,et al.  A method for selective conversion of allylic and benzylic alcohols to halides under neutral conditions , 1972 .