National study on the frequency, types, causes, and consequences of voluntarily reported emergency department medication errors.

BACKGROUND Medication errors contribute to significant morbidity, mortality, and costs to the health system. Little is known about the characteristics of Emergency Department (ED) medication errors. STUDY OBJECTIVE To examine the frequency, types, causes, and consequences of voluntarily reported ED medication errors in the United States. METHODS A cross-sectional study of all ED errors reported to the MEDMARX system between 2000 and 2004. MEDMARX is an anonymous, confidential, de-identified, Internet-accessible medication error-reporting program designed to allow hospitals to report, track, and share error data in a standardized format. RESULTS There were 13,932 medication errors from 496 EDs analyzed. The error rate was 78 reports per 100,000 visits. Physicians were responsible for 24% of errors, nurses for 54%. Errors most commonly occurred in the administration phase (36%). The most common type of error was improper dose/quantity (18%). Leading causes were not following procedure/protocol (17%), and poor communication (11%), whereas contributing factors were distractions (7.5%), emergency situations (4.1%), and workload increase (3.4%). Computerized provider order entry caused 2.5% of errors. Harm resulted in 3% of errors. Actions taken as a result of the error included informing the staff member who committed the error (26%), enhancing communication (26%), and providing additional training (12%). Patients or family members were notified about medication errors 2.7% of the time. CONCLUSION ED medication errors may be a result of the acute, crowded, and fast-paced nature of care. Further research is needed to identify interventions to reduce these risks and evaluate the effectiveness of these interventions.

[1]  N. Laird,et al.  Incidence of adverse drug events and potential adverse drug events , 1995 .

[2]  G. Rosenthal,et al.  An empirically derived taxonomy of factors affecting physicians’ willingness to disclose medical errors , 2006, Journal of General Internal Medicine.

[3]  C. Wild Building a safer health system , 2001 .

[4]  D. Bates,et al.  Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. , 1998, JAMA.

[5]  J. Tritter,et al.  Medical error: a discussion of the medical construction of error and suggestions for reforms of medical education to decrease error , 2001, Medical education.

[6]  D. Bates,et al.  The Costs of Adverse Drug Events in Hospitalized Patients , 1997 .

[7]  R. Niska,et al.  National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary. , 2008, National health statistics reports.

[8]  Schnell Br A study of unit-dose drug distribution in four Canadian hospitals. , 1976 .

[9]  T. Brennan,et al.  The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. , 1991, The New England journal of medicine.

[10]  Brian L. Erstad,et al.  Medication errors and adverse drug events in an intensive care unit: Direct observation approach for detection , 2006, Critical care medicine.

[11]  Todd R. Johnson,et al.  Evaluating a medical error taxonomy , 2002, AMIA.

[12]  Felice C. Frankel At the Breaking Point , 2003, American Scientist.

[13]  David W. Bates,et al.  The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group , 1997 .

[14]  David W Bates,et al.  Comparison of methods for detecting medication errors in 36 hospitals and skilled-nursing facilities. , 2002, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[15]  W. Levinson,et al.  Factors influencing perioperative nurses' error reporting preferences. , 2007, AORN journal.

[16]  T. Kirsch,et al.  The effects of ambulance diversion: a comprehensive review. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[17]  N. Laird,et al.  Incidence of Adverse Drug Events and Potential Adverse Drug Events: Implications for Prevention , 1995 .

[18]  P. Friedmann,et al.  Appropriateness of medication selection for older persons in an urban academic emergency department. , 1999, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[19]  Thomas Bottoni,et al.  Improving medication safety and patient care in the emergency department. , 2003, Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association.

[20]  A. Wu,et al.  Handling Hospital Errors: Is Disclosure the Best Defense? , 1999, Annals of Internal Medicine.

[21]  A. Wall,et al.  Book ReviewTo Err is Human: building a safer health system Kohn L T Corrigan J M Donaldson M S Washington DC USA: Institute of Medicine/National Academy Press ISBN 0 309 06837 1 $34.95 , 2000 .

[22]  D. Classen,et al.  Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. , 1997, JAMA.

[23]  Y. Han,et al.  Unexpected Increased Mortality After Implementation of a Commercially Sold Computerized Physician Order Entry System , 2005, Pediatrics.

[24]  Sharon B. Schweikhart,et al.  Perceived Barriers to Medical‐Error Reporting: An Exploratory Investigation , 2002, Journal of healthcare management / American College of Healthcare Executives.

[25]  Jane Garbutt,et al.  Using focus groups to understand physicians' and nurses' perspectives on error reporting in hospitals. , 2004, Joint Commission journal on quality and safety.

[26]  C. Camargo,et al.  Inappropriate Medication Administration to the Acutely Ill Elderly: A Nationwide Emergency Department Study, 1992–2000 , 2004, Journal of the American Geriatrics Society.

[27]  C. Patterson,et al.  Joint Commission on Accreditation of Healthcare Organizations. , 1995 .

[28]  Stacey L Cole,et al.  Medication errors among acutely ill and injured children treated in rural emergency departments. , 2007, Annals of emergency medicine.

[29]  S. Schenkel Promoting patient safety and preventing medical error in emergency departments. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[30]  P. Rappaport,et al.  A study pre and post unit dose conversion in a pediatric hospital. , 1991, The Canadian journal of hospital pharmacy.

[31]  Peter J Pronovost,et al.  A practical tool to learn from defects in patient care. , 2006, Joint Commission journal on quality and patient safety.

[32]  T. Brennan,et al.  INCIDENCE OF ADVERSE EVENTS AND NEGLIGENCE IN HOSPITALIZED PATIENTS , 2008 .

[33]  Sue M. Evans,et al.  Attitudes of doctors and nurses towards incident reporting: a qualitative analysis , 2004, The Medical journal of Australia.

[34]  A. Egberts,et al.  Adverse drug events in hospitalized patients A comparison of doctors, nurses and patients as sources of reports , 1999, European Journal of Clinical Pharmacology.

[35]  L. Kohn,et al.  To Err Is Human : Building a Safer Health System , 2007 .