Inflammasomes of the intestinal epithelium.
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[1] R. Vance,et al. The NLRP1 inflammasomes , 2015, Immunological reviews.
[2] R. Flavell,et al. Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome , 2015, Nature Communications.
[3] P. Schneider,et al. Epithelial NAIPs protect against colonic tumorigenesis , 2015, The Journal of experimental medicine.
[4] S. Peterson,et al. Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota , 2015, Clinical and experimental immunology.
[5] T. Williams,et al. The NLRP1 Inflammasome Attenuates Colitis and Colitis-Associated Tumorigenesis , 2015, The Journal of Immunology.
[6] S. Rutz,et al. Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. , 2015, Immunity.
[7] R. Vance. The NAIP/NLRC4 inflammasomes. , 2015, Current opinion in immunology.
[8] F. Shao,et al. Non-canonical Activation of Inflammatory Caspases by Cytosolic Lps in Innate Immunity This Review Comes from a Themed Issue on Innate Immunity Lps Activation of a Caspase-11 'non-canonical Inflammasome' , 2022 .
[9] O. Harrison,et al. Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine , 2015, Mucosal Immunology.
[10] Z. Chen,et al. DAC can restore expression of NALP1 to suppress tumor growth in colon cancer , 2015, Cell Death and Disease.
[11] E. Kay,et al. Protective Role for Caspase-11 during Acute Experimental Murine Colitis , 2014, The Journal of Immunology.
[12] Si Ming Man,et al. Actin polymerization as a key innate immune effector mechanism to control Salmonella infection , 2014, Proceedings of the National Academy of Sciences.
[13] M. Kloor,et al. Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients , 2014, International journal of cancer.
[14] P. Li,et al. Inflammatory caspases are innate immune receptors for intracellular LPS , 2014, Nature.
[15] Lin Li,et al. Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome , 2014, Nature.
[16] W. Hardt,et al. Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa. , 2014, Cell host & microbe.
[17] J. Celli,et al. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. , 2014, Cell host & microbe.
[18] K. Bortoluci,et al. Emerging Concepts about NAIP/NLRC4 Inflammasomes , 2014, Front. Immunol..
[19] C. Abraham,et al. The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling through Innate Receptor–Initiated Pathways , 2014, The Journal of Immunology.
[20] F. Sutterwala,et al. Mechanism of NLRP3 inflammasome activation , 2014, Annals of the New York Academy of Sciences.
[21] Vishva M. Dixit,et al. Mechanisms and Functions of Inflammasomes , 2014, Cell.
[22] M. Lamkanfi,et al. Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulphate-induced colitis , 2014, Mucosal Immunology.
[23] D. Bumann,et al. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases , 2014, Nature.
[24] E. Elinav,et al. NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion , 2014, Cell.
[25] H. R. Payne,et al. Spatial Segregation of Virulence Gene Expression during Acute Enteric Infection with Salmonella enterica serovar Typhimurium , 2014, mBio.
[26] S. Nordlander,et al. NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen , 2013, Mucosal Immunology.
[27] K. Maloy,et al. Nlrp3 Activation in the Intestinal Epithelium Protects against a Mucosal Pathogen , 2013, Mucosal Immunology.
[28] B. Hallström,et al. The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling , 2014, Journal of Gastroenterology.
[29] B. Cookson,et al. Burning Down the House: Cellular Actions during Pyroptosis , 2013, PLoS pathogens.
[30] A. Kaser,et al. Paneth cells as a site of origin for intestinal inflammation , 2013, Nature.
[31] D. Powell,et al. Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock , 2013, Science.
[32] M. T. Wong,et al. Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4 , 2013, Science.
[33] H. Clevers,et al. Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications , 2013, Science.
[34] V. Young,et al. Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. , 2013, Gastroenterology.
[35] E. Elinav,et al. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer , 2013, Proceedings of the National Academy of Sciences.
[36] C. Sasakawa,et al. The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection. , 2013, Cell host & microbe.
[37] V. Hornung,et al. Of inflammasomes and pathogens – sensing of microbes by the inflammasome , 2013, EMBO molecular medicine.
[38] S. Rutz,et al. IL‐22, not simply a Th17 cytokine , 2013, Immunological reviews.
[39] Daniel E. Zak,et al. Caspase-11 Protects Against Bacteria That Escape the Vacuole , 2013, Science.
[40] R. Langer,et al. Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors. , 2013, Cancer cell.
[41] J. Rosenblatt,et al. New emerging roles for epithelial cell extrusion. , 2012, Current opinion in cell biology.
[42] Francis J. Huber,et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine , 2012, Nature.
[43] H. Herfarth,et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. , 2012, Immunity.
[44] J. Bertin,et al. NLRP6 Negatively Regulates Innate Immunity and Host Defense Against Bacterial Pathogens , 2012, Nature.
[45] B. Finlay,et al. Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection* , 2012, The Journal of Biological Chemistry.
[46] G. Núñez,et al. NLRC4-driven interleukin-1β production discriminates between pathogenic and commensal bacteria and promotes host intestinal defense , 2012, Nature Immunology.
[47] L. French,et al. Caspase-4 Is Required for Activation of Inflammasomes , 2012, The Journal of Immunology.
[48] G. Núñez,et al. Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine , 2012, The Journal of experimental medicine.
[49] S. Koch,et al. The life and death of epithelia during inflammation: lessons learned from the gut. , 2012, Annual review of pathology.
[50] M. Hornef,et al. The mammalian intestinal epithelium as integral player in the establishment and maintenance of host-microbial homeostasis. , 2012, Seminars in immunology.
[51] R. Uchiyama,et al. Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges , 2012, Mucosal Immunology.
[52] T. C. Weber,et al. Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes. , 2012, Cell host & microbe.
[53] B. Stecher,et al. The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen’s virulence factors, and the host’s mucosal immune response , 2012, Immunological reviews.
[54] Katherine A. Fitzgerald,et al. A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans , 2011, PLoS pathogens.
[55] D. Green,et al. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. , 2011, Cancer cell.
[56] Jinfeng Liu,et al. Non-canonical inflammasome activation targets caspase-11 , 2011, Nature.
[57] J. Bertin,et al. A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis , 2011, The Journal of Immunology.
[58] Yan Li,et al. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis , 2011, Inflammatory bowel diseases.
[59] Richard A. Flavell,et al. NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis , 2011, Cell.
[60] M. Chamaillard,et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury , 2011, Proceedings of the National Academy of Sciences.
[61] E. Elinav,et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4 , 2010, Proceedings of the National Academy of Sciences.
[62] A. Aderem,et al. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria , 2010, Nature Immunology.
[63] J. Celli,et al. Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia , 2010, Proceedings of the National Academy of Sciences.
[64] M. Russo,et al. A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes* , 2010, The Journal of Biological Chemistry.
[65] V. Dixit,et al. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella , 2010, The Journal of experimental medicine.
[66] Minsoo Kim,et al. Bacterial interactions with the host epithelium. , 2010, Cell host & microbe.
[67] H. Herfarth,et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer , 2010, The Journal of experimental medicine.
[68] M. Kastan,et al. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. , 2010, Immunity.
[69] N. Beauchemin,et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. , 2010, Immunity.
[70] M. Heikenwalder,et al. The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. , 2009, Cell host & microbe.
[71] W. Rabsch,et al. Motility allows S. Typhimurium to benefit from the mucosal defence , 2008, Cellular microbiology.
[72] S. Werner,et al. The Inflammasome Mediates UVB-Induced Activation and Secretion of Interleukin-1β by Keratinocytes , 2007, Current Biology.
[73] F. Martinon,et al. Inflammasome Components NALP 1 and 3 Show Distinct but Separate Expression Profiles in Human Tissues Suggesting a Site-specific Role in the Inflammatory Response , 2007, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[74] P. Gros,et al. Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila , 2007, Cellular microbiology.
[75] Graham F. Brady,et al. Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf* , 2006, Journal of Biological Chemistry.
[76] S. Akira,et al. The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 Type III Secretion Systems Allow Salmonella Serovar typhimurium to Trigger Colitis via MyD88-Dependent and MyD88-Independent Mechanisms1 , 2005, The Journal of Immunology.
[77] B. Stecher,et al. Flagella and Chemotaxis Are Required for Efficient Induction of Salmonella enterica Serovar Typhimurium Colitis in Streptomycin-Pretreated Mice , 2004, Infection and Immunity.
[78] J. Bertin,et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF‐κB and caspase‐1 , 2002, FEBS letters.
[79] F. Martinon,et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.
[80] A. Dutra,et al. Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever , 2000, Mammalian Genome.
[81] C. Moskaluk,et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. , 1998, Journal of immunology.