论文信息 - Squamous cell carcinoma of the vulva in a young woman with Crohn's disease.

Squamous cell carcinoma of the vulva in a young woman with Crohn's disease.

BACKGROUND Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract. Because Crohn's disease is transmural it may form fistulas to adjacent structures, including the perineum and vulva. CASE A 28-year-old white female with a history of Crohn's disease presented with a non-healing vulvar fistula. Biopsy revealed squamous cell carcinoma. CONCLUSION Young women may develop squamous cell carcinoma associated with fistulae of Crohn's disease.

S. Lele | J. Kesterson | S. South

[1] S. Robboy,et al. Mucinous adenocarcinoma arising in rectovaginal fistulas associated with Crohn's disease. , 2004, Gynecologic oncology.

[2] B. Korelitz. Carcinoma Arising in Crohn's Disease Fistulae: Another Concern Warranting Another Type of Surveillance , 1999, American Journal of Gastroenterology.

[3] M. Kulaylat,et al. Carcinoma arising in anorectal fistulas of crohn's disease , 1999, Diseases of the colon and rectum.

[4] A. Vernava. Cancer in chronic perianal fistulas of Crohn's disease , 1999, Diseases of the colon and rectum.

[5] A. Buchman,et al. Development of squamous cell carcinoma in chronic perineal sinus and wounds in Crohn's disease. , 1991, The American journal of gastroenterology.

[6] D. Sachar,et al. Extraintestinal cancers in inflammatory bowel disease , 1985, Cancer.

[7] J. Church,et al. The relationship between fistulas in Crohn's disease and associated carcinoma , 1985, Diseases of the colon and rectum.

[8] B. Korelitz. Carcinoma of the intestinal tract in Crohn's disease: results of a survey conducted by the National Foundation for Ileitis and colitis. , 1983, The American journal of gastroenterology.

[9] Y. C. Choo. Invasive squamous carcinoma of the vulva in young patients. , 1982, Gynecologic oncology.