Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

[1]  B. Koerber.  Online , 2014, LOG IN.

[2]  Matthew D. Schultz,et al.  Global Epigenomic Reconfiguration During Mammalian Brain Development , 2013, Science.

[3]  Y. Maegaki,et al.  MECP2 duplication syndrome in both genders , 2013, Brain and Development.

[4]  M. Sur,et al.  Mechanisms and therapeutic challenges in autism spectrum disorders: insights from Rett syndrome. , 2013, Current opinion in neurology.

[5]  Michael E. Greenberg,et al.  Activity-dependent neuronal signalling and autism spectrum disorder , 2013, Nature.

[6]  N. Heintz,et al.  MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system , 2012, Epigenetics & Chromatin.

[7]  Tao Wang,et al.  Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. , 2012, Human molecular genetics.

[8]  Bing Ren,et al.  Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine , 2012, Nature Protocols.

[9]  J. Neul.  The relationship of Rett syndrome and MECP2 disorders to autism , 2012, Dialogues in clinical neuroscience.

[10]  John D. Davis,et al.  Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients , 2012, Translational Psychiatry.

[11]  A. Guidotti,et al.  DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67‐positive neurons in the GAD67‐GFP mouse brain , 2012, The Journal of comparative neurology.

[12]  G. Hon,et al.  Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome , 2012, Cell.

[13]  Michael L. Gonzales,et al.  Phosphorylation of Distinct Sites in MeCP2 Modifies Cofactor Associations and the Dynamics of Transcriptional Regulation , 2012, Molecular and Cellular Biology.

[14]  Matthew W. Mosconi,et al.  Consensus Paper: Pathological Role of the Cerebellum in Autism , 2012, The Cerebellum.

[15]  H. Zoghbi,et al.  MeCP2: only 100% will do , 2012, Nature Neuroscience.

[16]  A. Bird,et al.  The role of MeCP2 in the brain. , 2011, Annual review of cell and developmental biology.

[17]  D. Grayson,et al.  Analysis of the GAD1 promoter: Trans-acting factors and DNA methylation converge on the 5′ untranslated region , 2011, Neuropharmacology.

[18]  G. Ming,et al.  Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain , 2011, Cell.

[19]  M. Biel,et al.  Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates , 2010, PloS one.

[20]  Haikuo Zhang,et al.  TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine , 2010, Cell Research.

[21]  Michael L. Gonzales,et al.  The Role of MeCP2 in Brain Development and Neurodevelopmental Disorders , 2010, Current psychiatry reports.

[22]  N. Heintz,et al.  The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.

[23]  Christina Thaller,et al.  Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus , 2009, Human molecular genetics.

[24]  A. Guidotti,et al.  Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation , 2008, Proceedings of the National Academy of Sciences.

[25]  I. Hertz-Picciotto,et al.  MECP2 promoter methylation and X chromosome inactivation in autism , 2008, Autism research : official journal of the International Society for Autism Research.

[26]  G. Blatt,et al.  Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications , 2007, Acta Neuropathologica.

[27]  J. LaSalle,et al.  Reduced MeCP2 Expression is Frequent in Autism Frontal Cortex and Correlates with Aberrant MECP2 Promoter Methylation , 2006, Epigenetics.

[28]  Eric C. Griffith,et al.  Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation , 2006, Neuron.

[29]  H. Zoghbi,et al.  Rett syndrome and MeCP2: linking epigenetics and neuronal function. , 2002, American journal of human genetics.

[30]  S. Schulz,et al.  Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices , 2002, Biological Psychiatry.

[31]  S. Fatemi,et al.  Dysregulation of Reelin and Bcl-2 Proteins in Autistic Cerebellum , 2001, Journal of autism and developmental disorders.

[32]  R. Jaenisch,et al.  Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice , 2001, Nature Genetics.

[33]  Colin A. Johnson,et al.  Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex , 1998, Nature.

[34]  A. Guidotti,et al.  The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders , 2013, Neuropsychopharmacology.

[35]  E. Kavalali,et al.  The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity , 2013, Neuropsychopharmacology.

[36]  A. Guidotti,et al.  Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA Demethylation in Major Psychosis , 2012, Neuropsychopharmacology.

[37]  L. Korzeniowski.  [On autism]. , 1967, Annales medico-psychologiques.