Octavius 4D characterization for flattened and flattening filter free rotational deliveries.

PURPOSE In this study the Octavius detector 729 ionization chamber (IC) array with the Octavius 4D phantom was characterized for flattening filter (FF) and flattening filter free (FFF) static and rotational beams. The device was assessed for verification with FF and FFF RapidArc treatment plans. METHODS The response of the detectors to field size, dose linearity, and dose rate were assessed for 6 MV FF beams and also 6 and 10 MV FFF beams. Dosimetric and mechanical accuracy of the detector array within the Octavius 4D rotational phantom was evaluated against measurements made using semiflex and pinpoint ionization chambers, and radiochromic film. Verification FF and FFF RapidArc plans were assessed using a gamma function with 3%∕3 mm tolerances and 2%∕2 mm tolerances and further analysis of these plans was undertaken using film and a second detector array with higher spatial resolution. RESULTS A warm-up dose of >6 Gy was required for detector stability. Dose-rate measurements were stable across a range from 0.26 to 15 Gy∕min and dose response was linear, although the device overestimated small doses compared with pinpoint ionization chamber measurements. Output factors agreed with ionization chamber measurements to within 0.6% for square fields of side between 3 and 25 cm and within 1.2% for 2 × 2 cm(2) fields. The Octavius 4D phantom was found to be consistent with measurements made with radiochromic film, where the gantry angle was found to be within 0.4° of that expected during rotational deliveries. RapidArc FF and FFF beams were found to have an accuracy of >97.9% and >90% of pixels passing 3%∕3 mm and 2%∕2 mm, respectively. Detector spatial resolution was observed to be a factor in determining the accurate delivery of each plan, particularly at steep dose gradients. This was confirmed using data from a second detector array with higher spatial resolution and with radiochromic film. CONCLUSIONS The Octavius 4D phantom with associated Octavius detector 729 ionization chamber array is a dosimetrically and mechanically stable device for pretreatment verification of FF and FFF RapidArc treatments. Further improvements may be possible through use of a detector array with higher spatial resolution (detector size and∕or detector spacing).

[1]  Dietrich Harder,et al.  Spatial resolution of 2D ionization chamber arrays for IMRT dose verification: single-detector size and sampling step width , 2007, Physics in medicine and biology.

[2]  D. González-Castaño,et al.  Evaluation of chamber response function influence on IMRT verification using 2D commercial detector arrays , 2012, Physics in medicine and biology.

[3]  Jason Cashmore,et al.  Lowering whole-body radiation doses in pediatric intensity-modulated radiotherapy through the use of unflattened photon beams. , 2011, International journal of radiation oncology, biology, physics.

[4]  F. Foppiano,et al.  Response to high-energy photons of PTW31014 PinPoint ion chamber with a central aluminum electrode. , 2008, Medical physics.

[5]  B Poppe,et al.  On the sensitivity of common gamma-index evaluation methods to MLC misalignments in Rapidarc quality assurance. , 2013, Medical physics.

[6]  D. Huyskens,et al.  On-line quality assurance of rotational radiotherapy treatment delivery by means of a 2D ion chamber array and the Octavius phantom. , 2007, Medical physics.

[7]  Per Munck af Rosenschöld,et al.  Patient QA systems for rotational radiation therapy: a comparative experimental study with intentional errors. , 2013, Medical physics.

[8]  Comparison of two commercial detector arrays for IMRT quality assurance. , 2007, Journal of applied clinical medical physics.

[9]  Pietro Mancosu,et al.  Pretreatment quality assurance of flattening filter free beams on 224 patients for intensity modulated plans: a multicentric study. , 2012, Medical physics.

[10]  L Kumaraswamy,et al.  Using an EPID for patient-specific VMAT quality assurance. , 2011, Medical physics.

[11]  David Sjostrom,et al.  Implementing RapidArc into clinical routine: a comprehensive program from machine QA to TPS validation and patient QA. , 2011, Medical physics.

[12]  S. Bhide,et al.  Dose-escalated intensity-modulated radiotherapy is feasible and may improve locoregional control and laryngeal preservation in laryngo-hypopharyngeal cancers. , 2012, International journal of radiation oncology, biology, physics.

[13]  Ravikumar Manickam,et al.  Comparison of four commercial devices for RapidArc and sliding window IMRT QA , 2011, Journal of applied clinical medical physics.

[14]  A. L. Angelini,et al.  Characterization of a 2D ion chamber array for the verification of radiotherapy treatments , 2005, Physics in medicine and biology.

[15]  D. Albers,et al.  Dosimetric evaluation of a 2D pixel ionization chamber for implementation in clinical routine , 2007, Physics in medicine and biology.

[16]  S. Padmanabhan,et al.  Characterization of responses of 2d array seven29 detector and its combined use with octavius phantom for the patient-specific quality assurance in rapidarc treatment delivery. , 2012, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[17]  Dietrich Harder,et al.  Three Dimensional Gamma-Index Analysis and Considerations of the Reference Level Definition for Dosimetric IMRT Plan Verification with 2D Ionisation Chamber Arrays , 2009 .

[18]  Jonathan G. Li,et al.  Comparison of two commercial detector arrays for IMRT quality assurance , 2009, Journal of Applied Clinical Medical Physics.

[19]  Fujio Araki,et al.  Angular dependence correction of MatriXX and its application to composite dose verification , 2012, Journal of applied clinical medical physics.

[20]  L. Kochian Author to whom correspondence should be addressed , 2006 .

[21]  Geoffrey G. Zhang,et al.  Evaluation of a new VMAT QA device, or the “X” and “O” array geometries , 2011, Journal of applied clinical medical physics.

[22]  F. Foppiano,et al.  Response to high-energy photons of PTW31014 PinPoint ion chamber with a central aluminum electrode. , 2008, Medical physics.

[23]  R. Kollhoff,et al.  Two-dimensional ionization chamber arrays for IMRT plan verification. , 2006, Medical physics.

[24]  Jonas D Fontenot,et al.  Comparison of action levels for patient-specific quality assurance of intensity modulated radiation therapy and volumetric modulated arc therapy treatments. , 2012, Medical physics.

[25]  Tommy Knöös,et al.  Current status and future perspective of flattening filter free photon beams. , 2011, Medical physics.

[26]  Sara Bresciani,et al.  Pretreatment patient-specific IMRT quality assurance: a correlation study between gamma index and patient clinical dose volume histogram. , 2012, Medical physics.