Novel antibacterial active quinolone-fluoroquinolone conjugates and 2D-QSAR studies.
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Ahmed Samir | A. Katritzky | C. D. Hall | S. Panda | A. S. Girgis | Alan R Katritzky | A. Samir | Siva S Panda | Sumaira Liaqat | Adel S Girgis | C Dennis Hall | Sumaira Liaqat | C. Hall
[1] Aladdin M. Srour,et al. Rational design, synthesis and molecular modeling studies of novel anti-oncological alkaloids against melanoma. , 2015, Organic & biomolecular chemistry.
[2] T. Baasov,et al. Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance , 2010, Expert opinion on drug discovery.
[3] Peter C. Jurs,et al. Descriptions of molecular shape applied in studies of structure/activity and structure/property relationships , 1987 .
[4] A. S. Girgis,et al. Synthesis and QSAR study of novel cytotoxic spiro[3H-indole-3,2'(1'H)-pyrrolo[3,4-c]pyrrole]-2,3',5'(1H,2'aH,4'H)-triones. , 2012, European journal of medicinal chemistry.
[5] Corwin Hansch,et al. Role of hydrophobic effects in mechanistic QSAR , 1999 .
[6] Riham F. George,et al. Synthesis, hypnotic properties and molecular modeling studies of 1,2,7,9-tetraaza-spiro[4.5]dec-2-ene-6,8,10-triones. , 2011, European journal of medicinal chemistry.
[7] R Gomeni,et al. Computer-assisted drug development (CADD): an emerging technology for designing first-time-in-man and proof-of-concept studies from preclinical experiments. , 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[8] K. Poole. Efflux-Mediated Resistance to Fluoroquinolones in Gram-Negative Bacteria , 2000, Antimicrobial Agents and Chemotherapy.
[9] A S Ivanov,et al. Strategy of computer-aided drug design. , 2003, Current drug targets. Infectious disorders.
[10] Alan R. Katritzky,et al. Rational design, synthesis, and 2D-QSAR study of anti-oncological alkaloids against hepatoma and cervical carcinoma , 2015 .
[11] D. Pompliano,et al. Drugs for bad bugs: confronting the challenges of antibacterial discovery , 2007, Nature Reviews Drug Discovery.
[12] ElSayed M Shalaby,et al. Regioselective synthesis, stereochemical structure, spectroscopic characterization and geometry optimization of dispiro[3H-indole-3,2′-pyrrolidine-3′,3″-piperidines] , 2014 .
[13] Riham F. George,et al. Stereoselective Synthesis, Structural and Spectroscopic Study of 4,5,11‐Triazatricyclo[6.2.1.0*2,6*]Undec‐5‐ene , 2016 .
[14] C. Hansch,et al. Searching for allosteric effects via QSAR. Part II. , 2003, Bioorganic & medicinal chemistry.
[15] R. Duval,et al. In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria. , 2007, The Journal of antimicrobial chemotherapy.
[16] I. Khanna,et al. Structure-activity relationships among DNA gyrase inhibitors. Synthesis and biological evaluation of 1,2-dihydro-4, 4-dimethyl-1-oxo-2-naphthalenecarboxylic acids as 1-carba bioisosteres of oxolinic acid. , 1984, Journal of medicinal chemistry.
[17] Mary Jane Ferraro,et al. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically : approved standard , 2000 .
[18] J. Bartlett,et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. , 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[19] T. Suzuki,et al. Quinolone antimicrobial agents. 1. Versatile new synthesis of 1-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. , 1978, Journal of medicinal chemistry.
[20] Aladdin M. Srour,et al. Microwave assisted synthesis and QSAR study of novel NSAID acetaminophen conjugates with amino acid linkers. , 2014, Organic & biomolecular chemistry.
[21] Christopher T. Walsh,et al. Antibiotics for Emerging Pathogens , 2009, Science.
[22] A. Katritzky,et al. Microwave-Assisted Synthesis of Biotin Conjugates with Quinolone Antibiotics via Amino Acids , 2014, Synthesis.
[23] S. Arabia,et al. Aminoacyl Benzotriazolides: Versatile Reagents for the Preparation of Peptides and Their Mimetics and Conjugates. , 2014 .
[24] L. McDonald,et al. Emergence of Reduced Susceptibility and Resistance to Fluoroquinolones in Escherichia coliin Taiwan and Contributions of Distinct Selective Pressures , 2001, Antimicrobial Agents and Chemotherapy.
[25] T. Long,et al. Trihydroxamate siderophore-fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus. , 2013, Bioconjugate chemistry.
[26] Girinath G. Pillai,et al. Synthesis, and QSAR analysis of anti-oncological active spiro-alkaloids. , 2015, Organic & biomolecular chemistry.
[27] B. Meunier,et al. Hybrid molecules with a dual mode of action: dream or reality? , 2008, Accounts of chemical research.
[28] A. Katritzky,et al. Quinine bis-conjugates with quinolone antibiotics and peptides: synthesis and antimalarial bioassay. , 2012, Organic & biomolecular chemistry.
[29] A. Katritzky,et al. Regioselective synthesis and theoretical studies of an anti-neoplastic fluoro-substituted dispiro-oxindole , 2015 .
[30] Changqin Hu,et al. Characterization of clinical Escherichia coli isolates from China containing transferable quinolone resistance determinants. , 2010, The Journal of antimicrobial chemotherapy.
[31] A. S. Girgis,et al. Regioselective synthetic approaches towards 1,2,8,9-tetraazadispiro[4.1.4.2]trideca-2,9-dien-6-ones of potential antimicrobial properties. , 2009, European journal of medicinal chemistry.
[32] Federico Corelli,et al. The 4-quinolone-3-carboxylic acid motif as a multivalent scaffold in medicinal chemistry. , 2009, Current medicinal chemistry.
[33] A. Katritzky,et al. Synthesis and antibacterial evaluation of amino acid-antibiotic conjugates. , 2014, Bioorganic & medicinal chemistry letters.
[34] G. Superti-Furga,et al. Rediscovering the sweet spot in drug discovery. , 2003, Drug discovery today.
[35] Riham F. George,et al. Synthesis and QSAR study of novel anti-inflammatory active mesalazine-metronidazole conjugates. , 2015, Bioorganic & medicinal chemistry letters.
[36] A. Katritzky,et al. Syntheses of Chiral N‐(Protected) Tri‐ and Tetrapeptide Conjugates , 2012, Chemical biology & drug design.