Mueller Optical Coherence Tomophraphy Technique for Non-Invasive Glucose Monitoring

A new and novel technique for non-invasive (NI) glucose sensing based on Mueller optical coherence tomography (OCT) technique is proposed. The feasibility of the proposed technique is demonstrated by detecting the optical rotation angle and depolarization index of phantom solution containing de-ionized water (DI), glucose solutions with concentrations ranging from 0~4000 mg/dL and 0.02% lipofundin. The practical applicability of the proposed technique is demonstrated by measuring the optical rotation angle and depolarization index properties of the human fingertip of normal healthy volunteers.