Regulation of Osteoblast Formation and Function

[1]  Arndt F Schilling,et al.  Leptin Inhibits Bone Formation through a Hypothalamic Relay A Central Control of Bone Mass , 2000, Cell.

[2]  Sundeep Khosla,et al.  The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[3]  J. Millán,et al.  Alkaline Phosphatase Knock‐Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[4]  G. Karsenty The genetic transformation of bone biology. , 1999, Genes & development.

[5]  P. Puigserver,et al.  Transcriptional activation of adipogenesis. , 1999, Current opinion in cell biology.

[6]  R. Derynck,et al.  Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass. , 1999, Development.

[7]  J. Aubin,et al.  Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro , 1999, Journal of cellular biochemistry.

[8]  R. Jilka,et al.  Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2 , 1999, Journal of cellular biochemistry.

[9]  R. Baron,et al.  Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development. , 1999, The Journal of clinical investigation.

[10]  P. Roberson,et al.  Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone. , 1999, The Journal of clinical investigation.

[11]  A. McMahon,et al.  Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. , 1999, Genes & development.

[12]  C. Damsky,et al.  Collagen Integrin Receptors Regulate Early Osteoblast Differentiation Induced by BMP‐2 , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  R. Oreffo,et al.  Interconversion potential of cloned human marrow adipocytes in vitro. , 1999, Bone.

[14]  P. Zandstra,et al.  Concentration-dependent internalization of a cytokine/cytokine receptor complex in human hematopoietic cells. , 1999, Biotechnology and bioengineering.

[15]  G. Karsenty,et al.  A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. , 1999, Genes & development.

[16]  J. Lagemaat,et al.  Strongly photonic macroporous gallium phosphide networks , 1999, Science.

[17]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[18]  P. Zandstra,et al.  Introduction to Stem Cell Biology in Vitro: Threshold to the Future , 1999, Annals of the New York Academy of Sciences.

[19]  J. Aubin Osteoprogenitor cell frequency in rat bone marrow stromal populations: Role for heterotypic cell–cell interactions in osteoblast differentiation , 1999, Journal of cellular biochemistry.

[20]  Pao-Tien Chuang,et al.  Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein , 1999, Nature.

[21]  J. Aubin,et al.  cDNA fingerprinting of osteoprogenitor cells to isolate differentiation stage-specific genes. , 1999, Nucleic acids research.

[22]  Renny T. Franceschi,et al.  Role of the α2-Integrin in Osteoblast-specific Gene Expression and Activation of the Osf2 Transcription Factor* , 1998, The Journal of Biological Chemistry.

[23]  T. Martin,et al.  Type I collagen influence on gene expression in UMR106-06 osteoblast-like cells is inhibited by genistein. , 1998, The Journal of endocrinology.

[24]  A. Parfitt,et al.  Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. , 1998, The Journal of clinical investigation.

[25]  R. Derynck,et al.  Osteoblastic Responses to TGF-β during Bone Remodeling , 1998 .

[26]  M. Nuttall,et al.  Human Trabecular Bone Cells Are Able to Express Both Osteoblastic and Adipocytic Phenotype: Implications for Osteopenic Disorders , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  A. Gupta,et al.  LIF, but Not IL‐6, Regulates Osteoprogenitor Differentiation in Rat Calvaria Cell Cultures: Modulation by Dexamethasone , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[28]  Y. Onoe Expression of Estrogen Receptor in Rat Bone , 1997 .

[29]  S. Nozawa,et al.  Expression of Estrogen Receptor β in Rat Bone. , 1997, Endocrinology.

[30]  G. Karsenty,et al.  Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence. , 1997, Molecular endocrinology.

[31]  J. Wozney,et al.  Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by bone morphogenetic protein-6. , 1997, Endocrinology.

[32]  A. Yamaguchi,et al.  Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. , 1997, The Journal of clinical investigation.

[33]  J. Aubin,et al.  The mature osteoblast phenotype is characterized by extensive plasticity. , 1997, Experimental cell research.

[34]  D. Prockop Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues , 1997, Science.

[35]  David J. Anderson,et al.  Regulatory Mechanisms in Stem Cell Biology , 1997, Cell.

[36]  J. Gimble,et al.  The function of adipocytes in the bone marrow stroma: an update. , 1996, Bone.

[37]  Allan Bradley,et al.  Increased bone formation in osteocalcin-deficient mice , 1996, Nature.

[38]  S. Aota,et al.  Fibronectin regulates calvarial osteoblast differentiation. , 1996, Journal of cell science.

[39]  Howard C. Tenenbaum,et al.  Expression of tissue non‐specific alkaline phosphatase stimulates differentiated behaviour in specific transformed cell populations , 1996, The Anatomical record.

[40]  R. Derynck,et al.  Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype , 1996, The Journal of cell biology.

[41]  Q. Chen,et al.  Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. , 1995, Developmental Biology.

[42]  T. Aigner,et al.  Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis , 1995, The Journal of cell biology.

[43]  K. Cheah,et al.  Tissue‐Specific and differential expression of alternatively spliced α1(II) collagen mRNAs in early human embryos , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[44]  F. Hughes,et al.  The effects of bone morphogenetic protein-2, -4, and -6 on differentiation of rat osteoblast cells in vitro. , 1995, Endocrinology.

[45]  Philippe Soriano,et al.  Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells. , 1995, Development.

[46]  A. Scutt,et al.  Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: Induction of a transition from nonadherent to adherent osteoblast precursors , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[47]  K. Mann,et al.  Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors. , 1995, The Journal of clinical investigation.

[48]  J. Aubin,et al.  Cellular expression of bone‐related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures , 1994, Journal of cellular physiology.

[49]  J. Aubin,et al.  Positive and negative immunoselection for enrichment of two classes of osteoprogenitor cells , 1991, The Journal of cell biology.

[50]  J. Aubin,et al.  Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate. , 1991, Bone and mineral.

[51]  J. Aubin,et al.  Parathyroid hormone reversibly suppresses the differentiation of osteoprogenitor cells into functional osteoblasts. , 1990, Endocrinology.

[52]  J. Aubin,et al.  Temporal sequence of interleukin 1 alpha-mediated stimulation and inhibition of bone formation by isolated fetal rat calvaria cells in vitro. , 1990, Cytokine.

[53]  M. Whyte Hypophosphatasia: Nature's Window on Alkaline Phosphatase Function in Humans , 2002 .

[54]  A. Canfield,et al.  Gene expression during vascular pericyte differentiation. , 1999, Critical reviews in eukaryotic gene expression.

[55]  L. Nilsson,et al.  Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells. , 1999, Blood.

[56]  J. Aubin,et al.  The Heterogeneity of the Osteoblast Phenotype , 1999 .

[57]  M. Owen Marrow Stromal Cell Culture: The marrow stromal cell system , 1998 .

[58]  J. Heersche,et al.  Progesterone stimulates proliferation and differentiation of osteoprogenitor cells in bone cell populations derived from adult female but not from adult male rats. , 1997, Bone.

[59]  D. Witte,et al.  Abnormal differentiation in MC3T3-E1 preosteoblasts expressing a dominant-negative type I collagen mutation. , 1996, Connective tissue research.

[60]  H. Kronenberg,et al.  Physiological roles for parathyroid hormone-related protein: lessons from gene knockout mice. , 1996, Vitamins and hormones.