A generalized Fitzhugh–Nagumo equation

Abstract In this paper we investigate mappings of the classical Fitzhugh–Nagumo equation to a generalized Fitzhugh–Nagumo equation. These mappings are invertible and transform the solutions of the classical Fitzhugh–Nagumo equation into solutions of the generalized Fitzhugh–Nagumo equation considered here. These mappings are found by considering the Lie point symmetries admitted by the classical Fitzhugh–Nagumo equation and the generalized Fitzhugh–Nagumo equation considered here. A particular example of a generalized Fitzhugh–Nagumo equation that satisfies the boundary conditions of the classical Fitzhugh–Nagumo equation is considered. Numerical solutions of the generalized Fitzhugh–Nagumo equation that do not satisfy the boundary conditions of the classical Fitzhugh–Nagumo equation are obtained by implementing the Method of Lines.

[1]  R. FitzHugh Impulses and Physiological States in Theoretical Models of Nerve Membrane. , 1961, Biophysical journal.

[2]  G. E. Prince,et al.  Dimsym and LIE: Symmetry determination packages Mathl. Comput. Modelling 25, 153-164, (1997). , 1997 .

[3]  S. Yoshizawa,et al.  An Active Pulse Transmission Line Simulating Nerve Axon , 1962, Proceedings of the IRE.

[4]  M. C. Nucci,et al.  The nonclassical method is more general than the direct method for symmetry reductions. An example of the Fitzhugh-Nagumo equation , 1992 .

[5]  D. Aronson,et al.  Multidimensional nonlinear di u-sion arising in population genetics , 1978 .

[6]  Yo Horikawa A spike train with a step change in the interspike intervals in the FitzHugh-Nagumo model , 1995 .

[7]  Elizabeth L. Mansfield,et al.  Symmetry reductions and exact solutions of a class of nonlinear heat equations , 1993, solv-int/9306002.

[8]  G. F. Newell Nonlinear Effects in the Dynamics of Car Following , 1961 .

[9]  Y. N. Kyrychko,et al.  Persistence of travelling wave solutions of a fourth order diffusion system , 2005 .

[10]  A. K. Head LIE, a PC program for Lie analysis of differential equations , 1993 .

[11]  Angela Slavova,et al.  CNN model for studying dynamics and travelling wave solutions of FitzHugh-Nagumo equation , 2003 .

[12]  F. Mahomed,et al.  Approximate conditional symmetries and approximate solutions of the perturbed Fitzhugh-Nagumo equation , 2005 .

[13]  Takuji Kawahara,et al.  Interactions of traveling fronts: an exact solution of a nonlinear diffusion equation , 1983 .

[14]  G. Baumann,et al.  Symmetry Analysis of Differential Equations with Mathematica , 2000 .

[15]  A. K. Head,et al.  Dimsym and LIE: Symmetry determination packages , 1997 .

[16]  G. Bluman,et al.  Symmetries and differential equations , 1989 .