Ensembl 2015

Ensembl (http://www.ensembl.org) is a genomic interpretation system providing the most up-to-date annotations, querying tools and access methods for chordates and key model organisms. This year we released updated annotation (gene models, comparative genomics, regulatory regions and variation) on the new human assembly, GRCh38, although we continue to support researchers using the GRCh37.p13 assembly through a dedicated site (http://grch37.ensembl.org). Our Regulatory Build has been revamped to identify regulatory regions of interest and to efficiently highlight their activity across disparate epigenetic data sets. A number of new interfaces allow users to perform large-scale comparisons of their data against our annotations. The REST server (http://rest.ensembl.org), which allows programs written in any language to query our databases, has moved to a full service alongside our upgraded website tools. Our online Variant Effect Predictor tool has been updated to process more variants and calculate summary statistics. Lastly, the WiggleTools package enables users to summarize large collections of data sets and view them as single tracks in Ensembl. The Ensembl code base itself is more accessible: it is now hosted on our GitHub organization page (https://github.com/Ensembl) under an Apache 2.0 open source license.

Alessandro Vullo | Daniel R. Zerbino | Laurent Gil | Paul Flicek | Fiona Cunningham | Jennifer L. Harrow | Miguel Pignatelli | Matthieu Muffato | Leo Gordon | Ewan Birney | Nathan Johnson | Peter Clapham | Daniel Barrell | Kathryn Beal | Stephen Keenan | William M. McLaren | Magali Ruffier | Kieron R. Taylor | Andreas Kähäri | Anne Parker | Thomas Juettemann | Sarah E. Hunt | Rhoda Kinsella | Andy Yates | Konstantinos Billis | Denise Carvalho-Silva | Mateus Patricio | Emily Perry | Bronwen L. Aken | Carlos García-Girón | Thibaut Hourlier | Fergal J. Martin | Daniel N. Murphy | Rishi Nag | Amonida Zadissa | Stephen M. J. Searle | Stephen J. Trevanion | Daniel Sheppard | Thomas Maurel | Guy Coates | Anja Thormann | M. Ridwan Amode | Stephen Fitzgerald | Sophie H. Janacek | Harpreet Singh Riat | Steven P. Wilder | Giulietta Spudich | Bert Overduin | Simon Brent | Fergal J. Martin | E. Birney | J. Harrow | D. Barrell | A. Zadissa | S. Searle | F. Cunningham | W. McLaren | P. Flicek | D. Zerbino | S. Hunt | Kathryn Beal | Guy Coates | Stephen Fitzgerald | Nathan Johnson | Andreas Kähäri | B. Overduin | Anne Parker | G. Spudich | S. Trevanion | S. Keenan | Konstantinos Billis | Magali Ruffier | M. Pignatelli | L. Gil | H. Riat | A. Thormann | D. Carvalho-Silva | Thomas Juettemann | Daniel Sheppard | S. Wilder | Emily Perry | R. Kinsella | Simon Brent | M. Amode | P. Clapham | C. García-Girón | Leo Gordon | Thibaut Hourlier | Thomas Maurel | Rishi Nag | Mateus Patricio | K. Taylor | Alessandro Vullo | Matthieu Muffato | A. Yates | S. Hunt | C. G. Girón | S. Brent | Laurent Gil | Fiona Cunningham | Kathryn M Beal | A. Vullo | Giulietta Spudich

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