论文信息 - Optimization of fed-batch fermentors by iterative dynamic programming.

Optimization of fed-batch fermentors by iterative dynamic programming.

By using penalty functions to handle state constraints, iterative dynamic programming can be used in a straightforward manner for the optimization of fed-batch fermentors. No computational difficulties were encountered and better results are obtained than previously reported in the literature for a fed-batch fermentor for biosynthesis of penicillin.

R Luus | R. Luus

[1] H. Lim,et al. Computational algorithms for optimal feed rates for a class of fed‐batch fermentation: Numerical results for penicillin and cell mass production , 1986, Biotechnology and bioengineering.

[2] J. E. Cuthrell,et al. Simultaneous optimization and solution methods for batch reactor control profiles , 1989 .

[3] Rein Luus. Effect of the choice of final time in optimal control of nonlinear systems , 1991 .

[4] Rein Luus,et al. Sensitivity of optimal control to final state specification by a combined continuation and nonlinear programming approach , 1989 .

[5] R. Luus,et al. Multiplicity of solutions in the optimization of a bifunctional catalyst blend in a tubular reactor , 1992 .

[6] Rein Luus,et al. Application of dynamic programming to final state constrained optimal control problems , 1991 .

[7] R. Luus. Application of dynamic programming to high-dimensional non-linear optimal control problems , 1990 .