OUTCOME OF PITUITARY ADENOMA RESECTION IN PATIENTS WITH HYPERPROLACTINEMIA

Background: Pituitary gland that resides in the sellaturcica is a 60 milligram midline structure. The normal function includes secretion of certain hormones that directly or indirectly regulate the activity of other organs. Some major functions are being controlled by these hormones in the body. Postoperative hypopituitarism and hormonal recovery are well-known consequences of transsphenoidal pituitary adenoma removal. The purpose of the study is to assess the post-surgical changes in the levels of pituitary hormones and to determine the outcome of pituitary adenoma resection in patients with mild hyperprolactinemia Methods: A total of 39 pituitary tumor patients diagnosed on MRI were included in this study during the period of 24 months from Jan 2013 to December, 2014. Pre and post-operative prolactin levels were recorded on a pre designed questionnaire. Patients who have undergone surgery were kept under observation during the period of stay and were observed in follow-up until the third month after discharge. Results: Out of 39 patients, 17(43.58%) were males and 22(56.4%) were females. Satisfactory outcome of pituitary adenoma resection in patients with mild hyperprolactinemia was observed in 82.94%. Conclusion: It has been demonstrated that in expert surgical hands, normal anterior pituitary function is usually maintained and often improved following surgery of non-functioning pituitary adenomas. These results strengthen the indication for surgery in patients with hypopituitarism. However, care should be taken as these results are less likely to be reproduced by surgeons with limited experience in pituitary surgery.