S100A4 promotes liver fibrosis via activation of hepatic stellate cells.

[1]  J. Yamate,et al.  Histopathological Analysis of Rat Hepatotoxicity Based on Macrophage Functions: in Particular, an Analysis for Thioacetamide-induced Hepatic Lesions. , 2016, Food safety.

[2]  M. Grigorian,et al.  AB0203 S100A4 Serum Levels Correlate with Disease Activity, Skin Fibrosis and Lung Involvement in Systemic Sclerosis , 2014 .

[3]  X. Qin,et al.  Isolation and culture of hepatic stellate cells from mouse liver. , 2014, Acta biochimica et biophysica Sinica.

[4]  M. Grigorian,et al.  A3.16 Serum S100A4 correlates with skin fibrosis, lung involvement and disease activity in systemic sclerosis , 2014 .

[5]  R. Schwabe,et al.  Fate-tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its etiology , 2013, Nature Communications.

[6]  T. Leanderson,et al.  Common Interactions between S100A4 and S100A9 Defined by a Novel Chemical Probe , 2013, PloS one.

[7]  Takeshi Kimura,et al.  Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts. , 2013, Journal of molecular and cellular cardiology.

[8]  J. Fallowfield,et al.  Edinburgh Research Explorer Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis Differential Ly-6C expression identi fi es the recruited macrophage phenotype, which orchestrates the regression of murine liver fi brosis , 2022 .

[9]  T. Wynn,et al.  Mechanisms of fibrosis: therapeutic translation for fibrotic disease , 2012, Nature Medicine.

[10]  Christopher K. Glass,et al.  Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis , 2012, Proceedings of the National Academy of Sciences.

[11]  S. Friedman,et al.  Current status of novel antifibrotic therapies in patients with chronic liver disease , 2011, Therapeutic advances in gastroenterology.

[12]  A. Baranova,et al.  Non-Invasive markers for hepatic fibrosis , 2011, BMC gastroenterology.

[13]  C. Datz,et al.  Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver , 2010, Proceedings of the National Academy of Sciences.

[14]  Lieping Chen,et al.  This information is current as Hepatitis B Virus-Transgenic Mice Hepatitis to Hepatocellular Carcinoma in CD 137-Mediated Pathogenesis from Chronic , 2010 .

[15]  S. Almo,et al.  S100A4 Regulates Macrophage Chemotaxis , 2010, Molecular biology of the cell.

[16]  Kjetil Boye,et al.  S100A4 and metastasis: a small actor playing many roles. , 2010, The American journal of pathology.

[17]  J. Iredale,et al.  Liver fibrosis: cellular mechanisms of progression and resolution. , 2007, Clinical science.

[18]  V. Berezin,et al.  Molecular Mechanisms of Ca2+ Signaling in Neurons Induced by the S100A4 Protein , 2006, Molecular and Cellular Biology.

[19]  R Weiskirchen,et al.  Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets , 2006, Journal of cellular and molecular medicine.

[20]  J. Heeren,et al.  Knockdown of Hepatic ABCA1 by RNA Interference Decreases Plasma HDL Cholesterol Levels and Influences Postprandial Lipemia in Mice , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[21]  E. Neilson,et al.  Characterization of fibroblast-specific protein 1 in pulmonary fibrosis. , 2005, American journal of respiratory and critical care medicine.

[22]  S. Forbes,et al.  Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. , 2005, The Journal of clinical investigation.

[23]  D. Helfman,et al.  Characterization of the Metastasis-associated Protein, S100A4 , 2003, Journal of Biological Chemistry.

[24]  E. Neilson,et al.  The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. , 2003, Cancer research.

[25]  E. Neilson,et al.  Evidence that fibroblasts derive from epithelium during tissue fibrosis. , 2002, The Journal of clinical investigation.

[26]  A. Fischer,et al.  Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts. , 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

[27]  S. Seki,et al.  Hepatic expression of c‐Myb in chronic human liver disease , 1997, Hepatology.

[28]  M. Chojkier,et al.  Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity. , 1997, American journal of physiology. Gastrointestinal and liver physiology.

[29]  N. Kawada,et al.  Expression of heat-shock protein 47 in mouse liver , 1996, Cell and Tissue Research.

[30]  F. Strutz,et al.  Identification and characterization of a fibroblast marker: FSP1 , 1995, The Journal of cell biology.

[31]  K. Wake.  "Sternzellen" in the liver: perisinusoidal cells with special reference to storage of vitamin A. , 1971, The American journal of anatomy.

[32]  田巻 庸道.  Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts , 2013 .

[33]  D. Schuppan,et al.  Anti-fibrotic therapy: lost in translation? , 2012, Journal of hepatology.

[34]  Jinhua Zhang,et al.  Tumorigenesis and Neoplastic Progression FSP 1 Fibroblasts Promote Skin Carcinogenesis by Maintaining MCP-1-Mediated Macrophage Infiltration and Chronic Inflammation , 2010 .

[35]  S. Friedman.  Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. , 2008, Physiological reviews.

[36]  M. Pinzani.  Liver fibrosis , 2004, Springer Seminars in Immunopathology.

[37]  L. Mazzucchelli.  Protein S100A4: too long overlooked by pathologists? , 2002, The American journal of pathology.