Designing antibodies against LRRK2-targeted tau epitopes
暂无分享,去创建一个
[1] T. Golde,et al. Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau , 2017, Acta neuropathologica communications.
[2] M. Strong,et al. Threonine175, a novel pathological phosphorylation site on tau protein linked to multiple tauopathies , 2017, Acta neuropathologica communications.
[3] E. Gerhardt,et al. LRRK2 Promotes Tau Accumulation, Aggregation and Release , 2015, Molecular Neurobiology.
[4] G. Shaw,et al. Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2 , 2015, Journal of neuroscience research.
[5] S. Gerber,et al. LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5. , 2015, Biochemistry.
[6] Fumitaka Kawakami,et al. Leucine‐rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase‐3β , 2014, The FEBS journal.
[7] M. Farrer,et al. LRRK2 phosphorylates novel tau epitopes and promotes tauopathy , 2013, Acta Neuropathologica.
[8] F. Obata,et al. LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth , 2012, PloS one.
[9] E. Waxman,et al. Induction of Intracellular Tau Aggregation Is Promoted by α-Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau , 2011, The Journal of Neuroscience.
[10] M. Strong,et al. Tau phosphorylation at threonine‐175 leads to fibril formation and enhanced cell death: implications for amyotrophic lateral sclerosis with cognitive impairment , 2009, Journal of neurochemistry.
[11] K. Ashe,et al. Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L) , 2005, The Journal of Neuroscience.
[12] B. Hyman,et al. Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function , 2005, Science.
[13] M. Vitek,et al. Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. , 2001, Journal of cell science.
[14] John X. Morris,et al. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. , 1998, Science.
[15] W. Blackstock,et al. New Phosphorylation Sites Identified in Hyperphosphorylated Tau (Paired Helical Filament‐Tau) from Alzheimer's Disease Brain Using Nanoelectrospray Mass Spectrometry , 1998, Journal of neurochemistry.
[16] B. Winblad,et al. DEFECTIVE BRAIN MICROTUBULE ASSEMBLY IN ALZHEIMER'S DISEASE , 1986, The Lancet.
[17] S ORAM,et al. STAPHYLOCOCCI RESISTANT TO NEOMYCIN AND BACITRACIN. , 1965, Lancet.
[18] J. Ledbetter,et al. Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments. , 1996, Tissue antigens.