NUMERICAL APPROXIMATIONS TO THE TRANSPORT EQUATION ARISING IN NEURONAL VARIABILITY

This paper studies some finite difference approximations to find the numerical solution of first-order hyperbolic partial differential equation of mixed type, i.e., transport equation with point-wise delay and advance. We are interested in the challenging issues in neuronal sciences stemming from the mod- eling of neuronal variability. The resulting mathematical model is a first-order hyperbolic partial differential equation involving point-wise delay and advance which models the distribution of time intervals between successive neuronal firings. We construct, analyze, and implement explicit numerical schemes for solving such type of initial and boundary-interval problems. Analysis shows that numerical approximations are conditionally stable, consistent and conver- gent in discrete L 1 norm. Numerical approximations works irrespective the size of point-wise delay and advance. Some numerical tests are reported to validate the computational efficiency of the numerical approximations.

[1]  G. M.,et al.  Partial Differential Equations I , 2023, Applied Mathematical Sciences.

[2]  K. Sharma,et al.  Finite difference approximations for the first-order hyperbolic partial differential equation with point-wise delay , 2010, 1012.0974.

[3]  B. Perthame Transport Equations in Biology , 2006 .

[4]  Ernst Hairer,et al.  Implementing Radau IIA Methods for Stiff Delay Differential Equations , 2001, Computing.

[5]  J. Strikwerda Finite Difference Schemes and Partial Differential Equations, Second Edition , 2004 .

[6]  Wil H. A. Schilders,et al.  Uniform Numerical Methods for Problems with Initial and Boundary Layers , 1980 .

[7]  R. Stein A THEORETICAL ANALYSIS OF NEURONAL VARIABILITY. , 1965, Biophysical journal.

[8]  J. Strikwerda Finite Difference Schemes and Partial Differential Equations , 1989 .

[9]  L. Evans,et al.  Partial Differential Equations , 1941 .

[10]  E. Süli,et al.  Numerical Solution of Partial Differential Equations , 2014 .

[11]  K. Sharma,et al.  Numerical solution of first‐order hyperbolic partial differential‐difference equation with shift , 2010 .

[12]  R. LeVeque Numerical methods for conservation laws , 1990 .

[13]  G. Hedstrom,et al.  Numerical Solution of Partial Differential Equations , 1966 .

[14]  Nicola Guglielmi,et al.  Geometric proofs of numerical stability for delay equations , 2001 .

[15]  Jack K. Hale,et al.  Introduction to Functional Differential Equations , 1993, Applied Mathematical Sciences.

[16]  Paramjeet Singh,et al.  Hyperbolic partial differential-difference equation in the mathematical modeling of neuronal firing and its numerical solution , 2008, Appl. Math. Comput..

[17]  A. Bellen,et al.  Numerical methods for delay differential equations , 2003 .