Role of copper transporters in the uptake and efflux of platinum containing drugs.

[1]  G. Samimi,et al.  Intracellular localization and trafficking of fluorescein-labeled cisplatin in human ovarian carcinoma cells. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[2]  S. Howell,et al.  Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs. , 2005, Critical reviews in oncology/hematology.

[3]  D. Thiele,et al.  Mobilization of Intracellular Copper Stores by the Ctr2 Vacuolar Copper Transporter* , 2004, Journal of Biological Chemistry.

[4]  M. Petris,et al.  Cisplatin Stabilizes a Multimeric Complex of the Human Ctr1 Copper Transporter , 2004, Journal of Biological Chemistry.

[5]  G. Samimi,et al.  The role of copper transporters in the development of resistance to Pt drugs. , 2004, Journal of inorganic biochemistry.

[6]  Stephen B. Howell,et al.  Cisplatin Rapidly Down-regulates Its Own Influx Transporter hCTR1 in Cultured Human Ovarian Carcinoma Cells , 2004, Clinical Cancer Research.

[7]  G. Samimi,et al.  The Copper Influx Transporter Human Copper Transport Protein 1 Regulates the Uptake of Cisplatin in Human Ovarian Carcinoma Cells , 2004, Molecular Pharmacology.

[8]  G. Samimi,et al.  Increased Expression of the Copper Efflux Transporter ATP7A Mediates Resistance to Cisplatin, Carboplatin, and Oxaliplatin in Ovarian Cancer Cells , 2004, Clinical Cancer Research.

[9]  G. Samimi,et al.  Confocal Microscopic Analysis of the Interaction between Cisplatin and the Copper Transporter ATP7B in Human Ovarian Carcinoma Cells , 2004, Clinical Cancer Research.

[10]  L. Erickson,et al.  Evaluation of mitoxantrone accumulation and multidrug resistance transporters in prostate cancer cells , 2004 .

[11]  G. Samimi,et al.  Cross-resistance to cisplatin in cells with acquired resistance to copper , 2004, Cancer Chemotherapy and Pharmacology.

[12]  Z. Siddik,et al.  Cisplatin: mode of cytotoxic action and molecular basis of resistance , 2003, Oncogene.

[13]  G. Samimi,et al.  The copper export pump ATP7B modulates the cellular pharmacology of carboplatin in ovarian carcinoma cells. , 2003, Molecular pharmacology.

[14]  M. Núñez,et al.  DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells. , 2003, American journal of physiology. Cell physiology.

[15]  D. Thiele,et al.  Copper-stimulated Endocytosis and Degradation of the Human Copper Transporter, hCtr1* , 2003, The Journal of Biological Chemistry.

[16]  S. Lutsenko,et al.  Function and Regulation of the Mammalian Copper-transporting ATPases: Insights from Biochemical and Cell Biological Approaches , 2003, The Journal of Membrane Biology.

[17]  Myriam Rochdi,et al.  Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper. , 2002, Cancer research.

[18]  S. Howell,et al.  The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae. , 2002, Molecular pharmacology.

[19]  D. Thiele,et al.  Characterization of Mouse Embryonic Cells Deficient in the Ctr1 High Affinity Copper Transporter , 2002, The Journal of Biological Chemistry.

[20]  I. Herskowitz,et al.  Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[21]  D. Thiele,et al.  Biochemical and Genetic Analyses of Yeast and Human High Affinity Copper Transporters Suggest a Conserved Mechanism for Copper Uptake* , 2002, The Journal of Biological Chemistry.

[22]  B. Tops,et al.  Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1). , 2002, The Biochemical journal.

[23]  Dominique L. Cosco,et al.  The copper transporter CTR1 provides an essential function in mammalian embryonic development , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[24]  D. Thiele,et al.  Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[25]  J. Mercer,et al.  The Menkes copper transporter is required for the activation of tyrosinase. , 2000, Human molecular genetics.

[26]  L. Møller,et al.  Characterization of the hCTR1 gene: genomic organization, functional expression, and identification of a highly homologous processed gene. , 2000, Gene.

[27]  M. Schaefer,et al.  Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[28]  T. Gilliam,et al.  Characterization of the Interaction between the Wilson and Menkes Disease Proteins and the Cytoplasmic Copper Chaperone, HAH1p* , 1999, The Journal of Biological Chemistry.

[29]  T. Sugiyama,et al.  Restoration of Holoceruloplasmin Synthesis in LEC Rat after Infusion of Recombinant Adenovirus Bearing WND cDNA* , 1998, The Journal of Biological Chemistry.

[30]  S. Packman,et al.  Mutation Analysis and Expression of the Mottled Gene in the Macular Mouse Model of Menkes Disease , 1997, Pediatric Research.

[31]  Bing Zhou,et al.  hCTR1: a human gene for copper uptake identified by complementation in yeast. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[32]  J. Peppercorn,et al.  The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene , 1993, Nature Genetics.

[33]  S. Howell,et al.  Cellular accumulation of the anticancer agent cisplatin: a review. , 1993, British Journal of Cancer.

[34]  S. Packman,et al.  Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase , 1993, Nature Genetics.

[35]  Thomas W. Glover,et al.  Isolation of a partial candidate gene for Menkes disease by positional cloning , 1993, Nature Genetics.

[36]  Anthony P. Monaco,et al.  Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein , 1993, Nature Genetics.

[37]  S. Howell,et al.  Modulation of cis‐diamminedichloroplatinum(II) accumulation and sensitivity by forskolin and 3‐isobutyl‐1‐methylxanthine in sensitive and resistant human ovarian carcinoma cells , 1991, International journal of cancer.

[38]  M. Dobrota,et al.  Kinetics and mechanism of uptake of platinum-based pharmaceuticals by the rat small intestine. , 1990, Biochemical pharmacology.

[39]  A. Pa,et al.  Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. , 1990 .

[40]  R. Hromas,et al.  Decreased cisplatin uptake by resistant L1210 leukemia cells. , 1987, Cancer letters.