The SERIES project 'Experimental and Numerical Investigations of Nonlinearity in soils using Advanced Laboratory-Scaled models' (ENINALS) was focused on the centrifuge modeling of seismically-induced strains vs. stratigraphic features and it was applied to the heterogeneous alluvia of the Tiber River in the Rome historical centre. Four soil samples, representing two homogeneous soil columns (only clay and only sand respectively) and two heterogeneous soil columns (including a clay level between two sand ones) were tested in the IFSTTAR centrifuge. The applied dynamic input represents the maximum expected seismic action in Rome and it was reproduced at the centrifuge shaking device following three approaches: (i) a natural time history, (ii) an equivalent sinusoidal signal, and (iii) a multifrequential equivalent signal derived by the recently proposed LEMA_DES approach. The here reported preliminary results: (i) demonstrate the reliability of a 'cut and install' procedure for realizing the saturated multilayer samples; (ii) give new insights on the reliability of multifrequencial dynamic equivalent signals for scale-reduced analogical modeling.