A new process for acrylic acid synthesis by fermentative process.

With the synthesis of chemical products through biotechnological processes, it is possible to discover and to explore innumerable routes that can be used to obtain products of high added value. Each route may have particular advantages in obtaining a desired product, compared with others, especially in terms of yield, productivity, easiness to separate the product, economy, and environmental impact. The purpose of this work is the development of a deterministic model for the biochemical synthesis of acrylic acid in order to explore an alternative process. The model is built-up with the tubular reactor equations together with the kinetic representation based on the structured model. The proposed process makes possible to obtain acrylic acid continuously from the sugar cane fermentation.

[1]  Anthony J. Sinskey,et al.  Direct Demonstration of Lactate–Acrylate Interconversion in Clostridium Propionicum , 1983, Bio/Technology.

[2]  Rudolf Braun,et al.  Biotechnology for the production of commodity chemicals from biomass , 2000 .

[3]  Adrie J. J. Straathof,et al.  Feasibility of acrylic acid production by fermentation , 2005, Applied Microbiology and Biotechnology.

[4]  David F. Ollis,et al.  Biochemical Engineering Fundamentals , 1976 .

[5]  Dennis J. O'Brien,et al.  Biological Production of Acrylic Acid from Cheese Whey by Resting Cells of Clostridium propionicum , 1990 .

[6]  C. Mcgreavy,et al.  Reduced dynamic model of a fixed bed reactor , 1977 .

[7]  S. Jørgensen,et al.  A biochemically structured model for Saccharomyces cerevisiae. , 2001, Journal of biotechnology.

[8]  Eduardo Coselli Vasco de Toledo Modelagem, simulação e controle de reatores cataliticos de leito fixo , 1999 .

[9]  G Birol,et al.  A simple structured model for biomass and extracellular enzyme production with recombinant Saccharomyces cerevisiae YPB-G , 2002, Journal of Industrial Microbiology and Biotechnology.

[10]  K. Vorlop,et al.  Industrial bioconversion of renewable resources as an alternative to conventional chemistry , 2004, Applied Microbiology and Biotechnology.

[11]  R. M. Cotta,et al.  Enhanced lumped-differential formulations of diffusion problems , 1998 .

[12]  Bruce E. Dale,et al.  'Greening' the chemical industry: Research and development priorities for biobased industrial products , 2003 .

[13]  Rubens Maciel Filho,et al.  Desenvolvimento de modelos estruturados alternativos para o processo de produção de etanol , 2001 .