Factors Associated with In-Patient Mortality in the Rapid Assessment of Adult Earthquake Trauma Patients

Abstract Objective: To date, there is limited evidence for health care providers regarding the determinants of early assessment of poor outcomes of adult in-patients due to earthquakes. This study aimed to explore factors related to early assessment of adult earthquake trauma patients (AETPs). Methods: The data on 29,933 AETPs in the West China Earthquake Patients Database (WCEPD) were analyzed retrospectively. Then, 37 simple variables that could be obtained rapidly upon arrival at the hospital were collected. The least absolute shrinkage and selection operator (LASSO) regression analyses were performed. A nomogram was then constructed. Results: Nine independent mortality-related factors that contributed to AETP in-patient mortality were identified. The variables included age (OR:1.035; 95%CI, 1.027-1.044), respiratory rate ([RR]; OR:1.091; 95%CI, 1.050-1.133), pulse rate ([PR]; OR:1.028; 95%CI, 1.020-1.036), diastolic blood pressure ([DBP]; OR:0.96; 95%CI, 0.950-0.970), Glasgow Coma Scale ([GCS]; OR:0.666; 95%CI, 0.643-0.691), crush injury (OR:3.707; 95%CI, 2.166-6.115), coronary heart disease ([CHD]; OR:4.025; 95%CI, 1.869-7.859), malignant tumor (OR:4.915; 95%CI, 2.850-8.098), and chronic kidney disease ([CKD]; OR:5.735; 95%CI, 3.209-10.019). Conclusions: The nine mortality-related factors for ATEPs, including age, RR, PR, DBP, GCS, crush injury, CHD, malignant tumor, and CKD, could be quickly obtained on hospital arrival and should be the focal point of future earthquake response strategies for AETPs. Based on these factors, a nomogram was constructed to screen for AETPs with a higher risk of in-patient mortality.

[1]  T. Shimazu,et al.  Patient age affects sex-based differences in post-traumatic mortality: a national trauma registry study in Japan , 2021, European Journal of Trauma and Emergency Surgery.

[2]  E. Haut,et al.  Failure to Rescue in Geriatric Trauma: The Impact of Any Complication Increases with Age and Injury Severity in Elderly Trauma Patients , 2021, The American surgeon.

[3]  Hai Hu,et al.  Assessment of earthquake casualties and comparison of accuracy of five injury triage methods: evidence from a retrospective study , 2021, BMJ Open.

[4]  Ben J. Marafino,et al.  Rib Fracture Frailty Index: A risk stratification tool for geriatric patients with multiple rib fractures , 2021, The journal of trauma and acute care surgery.

[5]  Laxmi P. Dhakal,et al.  Incorporating age improves the Glasgow Coma Scale score for predicting mortality from traumatic brain injury , 2021, Trauma Surgery & Acute Care Open.

[6]  I. Kelman,et al.  Search without rescue? Evaluating the international search and rescue response to earthquake disasters , 2020, BMJ Global Health.

[7]  N. Simon,et al.  Seagull: lasso, group lasso and sparse-group lasso regularization for linear regression models via proximal gradient descent , 2020, BMC Bioinform..

[8]  A. Panangadan,et al.  Logistic LASSO Regression for Dietary Intakes and Breast Cancer , 2020, Nutrients.

[9]  Chengqi He,et al.  Related Factors Associated With Earthquake Inpatient Mortality , 2020, Disaster Medicine and Public Health Preparedness.

[10]  He Yu,et al.  Development and validation a nomogram for predicting the risk of severe COVID-19: A multi-center study in Sichuan, China , 2020, PloS one.

[11]  N. Ahmed,et al.  Early risk stratification of in hospital mortality following a ground level fall in geriatric patients with normal physiological parameters. , 2019, The American journal of emergency medicine.

[12]  H. Phelan,et al.  One Year Mortality in Geriatric Trauma Patients: Improving Upon the Geriatric Trauma Outcomes Score Utilizing the Social Security Death Index. , 2019, The journal of trauma and acute care surgery.

[13]  Andrea M Teng,et al.  Descriptive Epidemiology of New Zealand’s Highest Mortality Earthquake: Hawke’s Bay in 1931 , 2019, Scientific Reports.

[14]  D. Taylor-Robinson,et al.  Socioeconomic status and 30-day mortality after minor and major trauma: A retrospective analysis of the Trauma Audit and Research Network (TARN) dataset for England , 2018, PloS one.

[15]  Jingcheng Wang,et al.  Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis , 2018, Journal of Orthopaedic Surgery and Research.

[16]  S. Ruchholtz,et al.  The impact of pre-existing conditions on functional outcome and mortality in geriatric hip fracture patients , 2017, International Orthopaedics.

[17]  B. Pant,et al.  GERIATRIC CARE POST–MEGA EARTHQUAKE 2015 NEPAL , 2017 .

[18]  Dvora Kirshenbom,et al.  Older Age, Comorbid Illnesses, and Injury Severity Affect Immediate Outcome in Elderly Trauma Patients , 2017, Journal of emergencies, trauma, and shock.

[19]  F. Farrokhyar,et al.  Acute Traumatic Quadriplegia in Adults: Predictors of Acute in-Hospital Mortality. , 2017, Turkish neurosurgery.

[20]  H. Hai,et al.  Chief complaints associated with mortality involving civilian transport after Wen-chuan earthquake , 2014, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

[21]  M. Oncu,et al.  Evaluation of crush syndrome patients with extremity injuries in the 2011 Van Earthquake in Turkey. , 2014, Journal of clinical nursing.

[22]  S. Doocy,et al.  Mortality following the Haitian earthquake of 2010: a stratified cluster survey , 2013, Population Health Metrics.

[23]  Li Zhang,et al.  The clinical features and outcome of crush patients with acute kidney injury after the Wenchuan earthquake: differences between elderly and younger adults. , 2012, Injury.

[24]  Jinfeng Wang,et al.  Application of Bayesian geostatistical modeling for the assessment of risk for child mortality during the 2008 earthquake in Wenchuan, People's Republic of China. , 2012, Geospatial health.

[25]  K. Abe [Rescue system establishment for neurological patients in case of natural disastrous emergency]. , 2012, Rinsho shinkeigaku = Clinical neurology.

[26]  Trevor Hastie,et al.  Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.

[27]  P. Perel,et al.  Thromboprophylaxis for trauma patients. , 2010, The Cochrane database of systematic reviews.

[28]  Li Wang,et al.  Risk factors of earthquake inpatient death: a case control study , 2009, Critical care.

[29]  P. Royston,et al.  Selection of important variables and determination of functional form for continuous predictors in multivariable model building , 2007, Statistics in medicine.

[30]  I. Ercan,et al.  Survival analysis of the factors affecting in mortality in injured patients requiring dialysis due to acute renal failure during the Marmara earthquake: survivors vs non-survivors. , 2003, Clinical nephrology.

[31]  A. Ziv,et al.  An introduction to the Barell body region by nature of injury diagnosis matrix , 2002, Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention.

[32]  M. Grossman,et al.  When is an elder old? Effect of preexisting conditions on mortality in geriatric trauma. , 2002, The Journal of trauma.

[33]  T. Shimazu,et al.  Morbidity and mortality of hospitalized patients after the 1995 Hanshin-Awaji earthquake. , 1999, The American journal of emergency medicine.

[34]  T. Shimazu,et al.  Analysis of 372 patients with Crush syndrome caused by the Hanshin-Awaji earthquake. , 1997, The Journal of trauma.

[35]  J I Abrams,et al.  An Analysis of Prehospital Mortality in an Earthquake , 1994, Prehospital and Disaster Medicine.